pulmonary embolism and pulmonary hypertension Flashcards

1
Q

Examples of Thromboembolic disease

A

DVT, Pulmonary embolism

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2
Q

What is a pulmonary embolism?

A

A blockage of a pulmonary artery by a blood clot, fat, tumour or air

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3
Q

What is a pulmonary infarction

A

If blood flow and oxygen to the lung tissues is compromised the lung tissue may die

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4
Q

What type of DVT is most likely to embolise? (Proximal or distal)?

A

Proximal

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5
Q

What is the clinical presentation of DVT

A

Whol leg/calf involved depending on the site.

Swollen, hot, red, tender

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6
Q

What investigations are used for DVT

A

Ultrasound Doppler leg scan (1st line)

CT scan

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7
Q

Pulmonary Emboli clinical presentation

A

Large - Cardiovascular shock, low BP, central cyanosis, sudden death
Small recurrent - progressive dyspnoea, pulmonary hypertension and right heart failure

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8
Q

risk factors for DVT and PE

A
Thrombophilia 
Contraceptive pill (especially if smokes)
Pregnacny
Pelvic obstruction
Trauma (RTA)
Surgery
Immobility
Obesity
Pulmonary hypertension
Vasculitis
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9
Q

Prevention of DVT

A

early post-op movement
TED compression socks
calf muscle exercise
anticoagulants

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10
Q

History of presenting complaint (PE)

A
Shortness of breath (often acute onset)
Chest pain (pleuritic)
Haemoptysis 
Leg pain/swelling
Collapse / Sudden death
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11
Q

clinical features of PE

A

Tachycardia, tachypnoea, cyanosis, fever, low BP, crackles, rub, pleural effusion.
Arterial blood gases (ABGs)
CXR
Prediction scores (guide to likelihood of PE occuring)

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12
Q

Diagnosis and investigation of PE

A
Pulmonary Embolism Severity Index (PESI)
ECG
Troponin levels
Isotope lung scan
CT pulmonary angiogram (CTPA)
Leg/pelvic ultrasound
Echocardigram
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13
Q

Who has thrombolysis

A

Tissue plasminogen activator
For life-threatening massive PE
Patient has low BP, sustained sys ,90 mmHg for 15 mins

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14
Q

what is thrombolysis

A

the dissolution of a blood clot, especially as induced artificially by infusion of an enzyme into the blood.

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15
Q

pulmonary hypertension

A

“high flow, low pressure system”

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16
Q

symptoms of pulmonary hypertension

A
hypoxic
Multiple PE
Vasculitis
Drugs
HIV
Cardiac left to right shunt
17
Q

What is a cor pulmonale?

A

right heart disease secondary to lung disease
Fluid retention due to hypoxia
Can complicate COPD

18
Q

clinical signs of pulmonary hypertension and R heart failure

A

Central cyanosis if hypoxic
Dependent oedema
Raised JVP with V waves (due to secondary tricuspid regurg)
Right ventricular heave at left parasternal edge
Murmur of tricuspid regurgitation
Load P2
Enlarged liver (pulsatile

19
Q

pulmonary hypertension investigations

A
ECG
CXR
SaO2
Pulmonary function with DLCO
Echo