Pulmonary Edema, Emboli, Flashcards
Colloid osmotic pressure is also called
colloid oncotic pressure
During acute pulmonary edema, alveolar surface tension (increases/decreases)
increases
In pulmonary edema, increased hydrostatic pressure can be caused by
excessive sodium consumption
The normal colloid osmotic pressure in the pulmonary capillaries is
25-30 mmHG
Which of the following are considered noncardiogenic causes of increased capillary permeability?
head injury, pneumonia, noxious fumes like sulfur dioxide, alveolar hypoxia
What is the normal hydrostatic pressure in the pulmonary capillaries?
10-15 mmHg
Causes of cardiogenic pulmonary edema
excessive fluid administration CHF (left sided heart failure) arrhythmias systemic hypertension congenital heart defects mitral or aortic valve disease renal failure pulmonary embolus myocardial infarction/cardiac tamponade myocarditis (rheumatic heart disease) viral cardiomyopathies
The major pathologic/structural changes of the lungs associated with pulmonary edema:
- interstitial edema including engorgement of the perivascular and peribronchial spaces and alveolar wall interstitium
2 alveolar flooding
3 increased surface tension of alveolar fluids
4 alveolar shrinkage and atelectasis
5 frothy pink secretions
What happens when pulmonary hydrostatic pressure rises? (as when a patient with pul edema lies down)
pulmonary shunting increases, venus admixture increases, hypoxemia results
Acute pulmonary edema is treated with
O2, diurectics such as lasix, inotrophic drugs such as digoxin
.Pulmonary edema hydrostatic pressure -
ordinarily, hydrostatic pressure is about ____ and tends to move fluid out of the pulmonary capillaries into the interstitial space. This force is normally offset by colloid osmotic forces of about 25-30 mmHg.
10 to 15 mmHg
.Pulmonary edema hydrostatic pressure -
ordinarily, hydrostatic pressure is about 10-15 mmHg and tends to move fluid ____ of the pulmonary capillaries and ____the interstitial space. This force is normally offset by colloid osmotic forces of about 25-30 mmHg.
out
into
.Pulmonary edema hydrostatic pressure -
ordinarily, hydrostatic pressure is about ____ and tends to move fluid out of the pulmonary capillaries into the interstitial space. This force is normally offset by colloid osmotic forces of about _____ mmHg.
10-15 mmHg
25-30 mmHg
What is the normal oncotic pressure of the blood?
25-30 mmHg
Which of the following are causes of cardiogenic pulmonary edema?
- Excessive fluid administration
- Right ventricular failure
- Mitral valve disease
- Pulmonary embolus
1, 3, and 4 only
LEFT ventricular failure causes cardiogenic pulmonary edema
What abnormal ventilatory pattern is associated with pulmonary edema?
cheyne-stokes (progressively deeper, faster then decreasing to apnea)
What are some common CXR findings with pulmonary edema?
cardiomegaly, hilar prominence, Bat wing or butterfly pattern Kerley lines (A lines do not reach the pleura and are prevalent in the middle and upper lung- B lines are short, thin, horizontal extending inward from the pleural surface commonly seen in the bases)
When a patient has left sided heart failure, what is usually done to increase cardiac output?
give digitalis
Which are considered noncardiogenic causes of increased capillary permeability? 1. Head injury 2. Pneumonia 3 Sulfur Dioxide 4 Alveolar hypoxia
answer is all 1, 2, 3 & 4
Pulmonary edema can occur when the hydrostatic pressure within the pulmonary vascular system (also called wedge pressure) is
greater than 25 to 30 mmHg
The MOST common cause of pulmonary edema is
left sided heart failure
Pulmonary edema involves:
A. fluid moving from the pulmonary vascular system to the air spaces
B. fluid moving from the air spaces to the pulmonary vascular system
C. fluid moving from the pulmonary vascular system to the pleural spaces
D. fluid moving from the systemic vascular system to the air spaces
A. fluid moving from the pulmonary vascular system to the air spaces
Pulmonary edema involves fluid moving from the pulmonary vascular system to the air spaces of the lungs. With drowning, fluid can move from the air spaces to the pulmonary vascular system. A pleural effusion involves fluid moving from the pulmonary vascular system to the pleural spaces.
Decreased oncotic pressure can be caused by all of the following EXCEPT: A. dehydration B. severe malnutrition C. excessive intravenous fluids D. uremia
A. dehydration
Dehydration would increase the oncotic pressure. All of the other listed options, and others, can result in decreased oncotic pressure.
Compare and contrast oncotic and hydrostatic pressures
a. Oncotic - colloid osmotic pressure
b. Hydrostatic - pressure of nonmoving fluid
What happens in the Oxygenation Indices of a patient with pulmonary edema?
Increased Qs/Qt; Decreased D02; Normal V02; Normal C(a-v) O2, Increased O2 ER, Decreased Sv02
A blood clot that forms and remains in a vein is called _____. A blood clot that becomes dislodged and travels to another part of the body is called ____.
a thrombus
an embolus
The aortic and carotid sinus baroreceptors initiate what in response to a decreased systemic blood pressure?
increased heart rate and increased ventilatory (respiratory) rate
What is the upper limit of the normal MEAN pulmonary artery pressure? A. 5 mmHg B. 10 mm Hg C. 15 mm Hg D. 20 mm HG
15 mmHg is the upper limit of the normal MEAN pulmonary artery pressure
Pulmonary hypertension develops in pulmonary embolism because of:
1. Increased cross sectional area of the pulmonary vascular system
2. Vasoconstriction caused by humoral agent release
3. Vasoconstriction induced by decreased arterial oxygen pressure (PaO2)
4. Vasoconstriction induced by decreased alveolar oxygen pressure (PAO2)
1 and 3 only
2 and 4 only
1,2,3 only
2,3,4 only
1234
only 2 and 4
In severe pulmonary embolism, which of the following hemodynamic indices are commonly seen? 1. Decreased PVR 2. Increased PA 3. Decreased CVP 4. Increased PCWP 2 only 3 only 4 only 1 and 2 only
2 only
Emboli activate teh release of humoral agents such as seratonin histamine and prostaglandins into pulmonary circulation. These cause which: bronchoconstriction or bronchodilation?
bronchial constriction
Bronchial constriction, alveolar atelectasis, and consolidation lead to _____ alveolar ventilation relative to perfusion causing the V/Q ratio to do what?
decreased
decreased V/Q ratio
The safest most effective class of fast acting anticoagulant medication to prevent PE is:
low molecular weight heparin
THe ABG level of the pulmonary embolism patient will be:
decreased from normal
Pulmnary embolism initially results in
increased dead space ventilation
Name 2 anticoagulant agents
warfarin, heprin
Name 2 thrombolytic agents
urokinase, streptokinase
Chest xray findings with PEembolism
- often there are no CXR signs
- can see increased areas of density in infarcted areas
- dilation of the pulmonary arteries
- right ventricular cardiomegaly (cor pulmonale)
- small pleural effusion
Chest assessment findings with PEmolism can include
- right ventricular heave or lift
2. crackles, wheezes, pleural friction rub
Is chest expansion with PE increased, decreased or normal?
decreased
Are abnormal heart sounds associated with PE?
yes, increased second heart sound, splitting of second heart sound and 3rd heart sound of ventricular gallop
Oxygenation indices associated with PE are:
Qs/Qt? Do2? Vo2? C(a-v)? O2ER? SvO2?
Qs/Qt-- increased Do2 - decreased Vo2 - normal C(a-v) - normal O2ER - increased SvO2 - decreased
What are the major pathologic or structural change of the lungs associated with cardiogenic pulmonary edema?
- Interstitial edema
- alveolar flooding
- increased surface tension of alveolar fluids
- alveolar shrinkage and atelectasis
- frothy white or pink secretions throughout the tracheobronchial tree
pulmonary edema hydrostatic pressure ordinarily, hydrostatic pressure is about _______ and tends to move fluid out of the pulmonary capillaries into the interstitial space. This force is normally offset by colloid osmotic forces.
10 - 15 mmHg
the other name for colloid osmotic pressure is?
oncotic pressure
causes of pulmonary edema
cardiogenic:
arrhythmias, systemic hypertension, congenital heart defects, excessive fluid administration, left ventricular failure, mitral or aortic valve disease, myocardial infarction, cardiac tamponade pulmonary embolus renal failure, rheumatic heart disease, cardiomyopathies
non-cardiogenic:
allergic reaction to drugs, excessive sodium consumption, drug overdose, metal poisoning, chronic alcoholic ingestion, aspiration, cns stimulation, encephalitis, high altitudes
abnormal ventilatory patterns and findings associated with cardiogenic pulmonary edema
- cheyne-stokes respiration
- paroxysmal nocturnal dyspnea
- orthopnea
PFT findings for pulmonary edema
VT - normal or increase, IRV - decrease, ERV - decrease, RV - decrease, VC - decrease, IC - decrease, FRC - decrease, TLC - decrease, RV/TLC ratio - normal
ABG for mild to moderate pulmonary edema
acute alveolar hyperventilation w/ hypoxemia
pH - increase, paCO2 - decrease, HCO3 - slightly decrease, PaO2 - decrease
ABG for severe pulmonary edema
acute ventilatory failure w/ hypoxemia
pH - decrease, PaCO2 - increase, HCO3 - slightly increase, PaO2 - decrease
Oxygenation indices for pulmonary edema
QS/QT - increase, DO2 - decrease, VO2 - normal, C(a-V)O2 - normal, O2ER - increase, SVO2 - decrease
hemodynamic indices for pulmonary edema
CVP - increase, RAP - increase, PA - increase, PCWP - increase, CO - decrease, SV - decrease, SVI - decrease, CI -decrease, RVSWI - increase, LVSWI - decrease, PVR - increase , SVR - increase
normal range for PCWP
2 - 15 mmHG
Patients with cardiogenic pulmonary edema typically present with _______ sputum
pink frothy sputum
X-Ray findings for pulmonary edema
- bilateral fluffy opacities
- dilated pulmonary arteries
- left ventricular hypertrophy
- kerley A & B lines
- bat’s wings or butterfly pattern
- pleural effusion
medications for pulmonary edema
Antidyshythmic agents - prevent cardiac dysrhythmias
positive inotropic agents - improve cardiac output
cardiac workload reduction - afterload reduction
sodium and fluid retention therapy
albumin and mannitol - offset increase hydrostatic pressure
effect of CPAP on pulmonary edema
offset fluid accumulation and alveolar shrinkage associated with pulmonary edema