Pulmonary Dx Imaging Flashcards

1
Q

Imaging w/o radiation

A

U/s, MRI/MRA, Bronchoscopy

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2
Q

initial study for respiratory sx

A

CXR

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3
Q

What structures does CXR show

A

lung parenchyma, pleura, chest wall, diaphragm, mediastinum, hilum

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4
Q

Color of CXR

A
gas = black
fat = dark gray
soft tissue = light gray
bone calcification = nearly white
metal = white
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5
Q

Indications for CXE

A
SOB
persistent cough
hemoptysis
chest pain/injury
fever
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6
Q

CXR views

A

PA, AP, lateral, decubitus (PA and lateral are main ones; AP only done when patient can’t get out of bed – makes structures look bigger than they actually are)

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7
Q

ABCDEF’s of CXR

A
Airway
Bone
Cardiac
Diaphragm
Edges
Fields of lungs
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8
Q

Lateral view CXR

A

good for seeing lower lobes

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9
Q

apical lordotic view use

A

seeing something in apex of lung (ex. TB)

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10
Q

PA and lateral decubitus CXR use

A

determine pus vs. fluid (fluid moves b/c it is free flowing) – subpulmonic effusion

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11
Q

Benefits of CXR

A
non-invasive
low radiation
inexpensive
convenient
widely available
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12
Q

Pulmonary infarct

A

“Hampton’s hump”

triangular shape w/ base along chest wall; clot causes loss of circultation in lung leading to infarct

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13
Q

Risks/limitations of CXR

A

radiation exposure
pregnancy
can’t detect some conditions (small cancers, pulmonary emboli)

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14
Q

Why order a CT?

A
clarify abnormal CXR
dx clinical sx (SOB, cough, CP, fever)
characterize pulmonary nodules
detect and stage primary and metastatic neoplasms
lung cancer screening
evaluate mediastinal or hilar masses
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15
Q

Lung cancer screening

A

55-80 yo w/ 30 pack/yr hx and currently smoke OR quit w/i past 15 years

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16
Q

Types of CT scans

A
conventional
helical
high resolution (HRCT)
low dose CT
CT angiography
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17
Q

conventional CT

A

10 mm slice

“step and shoot”; 25-30 min

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18
Q

Helical CT

A

aka spiral CT
faster
continuous
<5 min

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19
Q

HRCT

A

better detail, 1 mm slice

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20
Q

Low dose CT

A

used for screening, less detail

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21
Q

Multidetector/multislice CT

A

64 x faster, but higher radiation

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22
Q

Benefits of CT

A
fast, widely available
detailed images
real-time imaging for bx
can be performed w/ implanted device
less expensive and sensitive to movement than MRI
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23
Q

Risk/limitations of CT

A
Radiation exposure
increased CA risk
fetal exposure during pregnancy
contrast issues
body habitus >450 lbs
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24
Q

Special populations for CT

A

peds: more radiosensitive, increased risk of leukemia and brain tumors
pregos: in utero exposure linked to ped CA mortality (always ask LMP before imaging)

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25
Q

CT contrast

A

iodine

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26
Q

Goal of contrast

A

enhance differences in densities of various structures

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27
Q

When to use contrast?

A

masses, CA, metastatic, obstructive processes, PE or dissection

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28
Q

Non-contrast use

A

eval of diffuse lung disease (HRCT)

follow up of primary nodules

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29
Q

Risk of CT w/ contrast

A

allergic rxn
contrast induced nephropathy
lactic acidosis if taking glucophage (metformin) – hold 48 hrs after imaging

30
Q

Allergic rxn from contrast

A

develops 5-60 min after

flushing, pruritus, urticaria, angioedema, bronchospasm, and wheezing, stridor, HTN, loss of consciousness

31
Q

Risk factor for allergic rxn to contrast

A

prior rxn
asthma
atopy

32
Q

How to avoid contrast rxn

A

pre-treat w/:

Prednisone & Diphenhydramine (Benadryl)

33
Q

Contrast induced nephropathy

A

serum Cr >25% from baseline or >0.5 mg/dL

usually reversible

Caution using contrast in pts w/ impaired kidney function

34
Q

Impaired kidney function considered

A

Cr >1.5 or GFR <60

35
Q

When to check renal function before iodine contrast

A
age >60
hx of renal disease  (dialysis, single kidney, kidney transplant, renal cancer, renal surgery)
HTN treated w/ meds
DM
Glucophage (metformin)
36
Q

Glucophage

A

eGFR >30 - med doesn’t need to be withheld

AKI or severe CKD w/ eGFR <30 - hold metformin x 48 hrs; resume after eval of renal funciton (avoiding lactic acidosis)

37
Q

Pulmonary Angiography types

A

CTA or direct pulmonary angiography (catheter into patients)

38
Q

Angiography use

A

assess vasculature; done w/ CT, MRI or X-ray (direct)

39
Q

CTA

A

blood vessel detail; used for suspected PE, aortic dissection , SVC syndrome

identify vascular malformations

assess pulmonary arterial invasion by neoplasm

40
Q

CTPA benefits

A

less invasive than direct
precise anatomical guidance if surgery warranted
safer than conventional angiography

41
Q

Risks/limitations of CTPA

A
can miss sub-segmental PES
allergy to contrast
nephrotoxicity
radiation
body habitus >450 lbs
42
Q

Gold standard for PE

A

direct pulmonary angiography

43
Q

What is direct pulmonary angiography?

A

needle/catheter inserted into right femoral or internal jugular vein –> R side heart –> pulm arteries

dye injected, x-rays taken

44
Q

When do you use direct pulmonary angiography

A

if V/Q or CTPA inconclusive but still have high clinical suspicion

45
Q

Risk of direct pulmonary angiography

A
bleeding/hematoma at insertion site
heart arrhythmia
allergic rxn to contrast
impaired kidney function
radiation
46
Q

MRI use

A

limited in pulm disease

hilar or mediastinal densities, sulcus tumors, cysts, lesions of chest wall

if patient has allergy to iodine or renal disease (GFR <60)

47
Q

Benefits of MRI

A

no bone artifact as w/ CT

no radiation

48
Q

Contrast for MRI

A

gadolinium

49
Q

Limitations of MRI/MRA

A

pt must remain still
clautrophobia
body habitus
risk of nephrogenic systemic fibrosis (irreversible) - avoid gadolinium if GF <30 ml/min

50
Q

Contraindications of MRI/MRA

A

pacemaker/defibrillator
metal in eye
aneurysm clip
cochlear implant

51
Q

Nuclear imaging types

A

VQ

PET scan

52
Q

VQ use

A

PE

pre-op assessment prior to lung resection

53
Q

VQ mismatch

A

imbalance of blood flow and ventilation

54
Q

V/Q scan phases

A

IV phase: tech-99m (labeled to human albumin) injected and follows blood flow (perfusion)

inhalation phase: radio-labeled xenon gas demonstrates distribution of ventilation

55
Q

Benefits of V/Q

A

allergic rxn to radiopharm is rare
low dose radiation
Test of choice for PE in pregnant women
useful in estimating postop reserve capacity for those undergoing lung resection

56
Q

TOC for PE in pregos

A

V/Q

57
Q

Limitations of V/Q scan

A

sensitive for PE, but poorly specific (high false positives)

best utilized in those w/ normal CXR
no absolute contraindications

58
Q

PET scan

A

physiologic images

radiation emitted from fluorodeoxyglucose (FDG)

59
Q

FDG

A

radioactive glucose

accumulates in tissues/organs w/ high metabolic activity (cancer cells)

60
Q

measurement of PET scan

A

SUV >2.5 raises probability of malignancy

61
Q

Use of PET scan

A

detect cancer
metastasis
examine effects of cancer therapy

62
Q

Benefits of PET scan

A

detect changes in anatomy before apparent w/ CT and MRI

radioactivity is short-lived

63
Q

Limitations of PET scan

A

radiation
false + (inflammatory lesions, granulomas)
false - w/ slow growing tumors
time sensitive - radioactive substance decays quickly
high cost

64
Q

Indications for U/S

A

bedside detection of pleural fluid or pneumothorax
guidance for thoracentesis
guidance for placement of thoracostomy tubes

65
Q

Benefits of u/s

A

no radiation

portable units

66
Q

u/s of normal lung

A

seashore sign

67
Q

barcode or stratosphere sign

A

pneumothorax (no motion lung)

68
Q

Broncoscopy indications

A
pneumonia, hemoptysis, cough
dx tracheoesophageal fistulas and tracheobronchomalacia
tissue sampling
removal of excess mucus or FBs
ET tube placement
69
Q

Rigid bronchoscopy

A

used for pts w/ obstruction of trachea or a proximal bronchus; for removal of debris (FB)

70
Q

Benefits of bronchoscopy

A
safe
low complications (nasal discomfort, sore throat, mild hemoptysis; hemorrhage, pneumothorax, Hypotension, arrhythmia)
71
Q

Contraindications for bronchscopy

A

severe refractory hypoxia
risk of bleeding (anticoagulants, coagulopathy)
risk of respiratory and CV decompensation (asthma or COPD exacerbation current or recent MI, poorly controlled CHF, life threatening arrhythmias)