Pulmonary Disease Flashcards

1
Q

What are some common post op resp complications? How common are they?

A
  1. 8% of all surgeries
    - atelectasis
    - infection (pneumonia, bronchitis)
    - bronchospasm
    - exacerbation of COPD
    - prolonged mechanical ventilation and resp failure (>48hrs)
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2
Q

What is the most common type of pneumonia? what are some findings?

A

CXR - infiltrate in right middle zone, right heart blurred but preserved right hemidiaphragm

CT chest - alveolar spaces opacified with air bronchograms

tend to see RML pneumonia as aspiration most direct route.

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3
Q

What is the pathophysiology for post op pulmonary complications?

A

1) Change in physiologic parameters
- vital capacity reduced, FRC and tidal volume reduction
- increased resp rate (?pain)
2) Diaphragmatic dysfunction
- damage to phrenic nerve (thoracic)
3) Pain and splinting
4) Reduced resp drive and drowsiness (opioids/anaesthesia)
5) Cough attenuation
- - retained airway secretions
6) microatelectasis

increased atelectasis
shunting
impaired mucous clearance
pnuemonia

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4
Q

What are some risk factors that contribute to likelihood of post op cx?

A

Patient factors

  • advanced age
  • ASA class >2 (ASA 3 or higher)
  • COPD (meds)
  • active asthma
  • smoking
  • general health (cog/function)
  • CCF (orthopnoea, PND, oedema)
  • OSA (snoring, daytime somnalence, STOPBANG)
  • pul HTN

Procedure factors

  • aortic aneurysm repair
  • surg location (incisional site from diaphragm)
  • emerg surg
  • prolonged surgery (>4hrs)
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5
Q

What does the STOP BANG acronym stand for?

A
Snoring 
Tired 
Observed you stop breathing 
Pressure - high SBP 
BMI - >35 
Age - >50 
Neck size (43cm in males 41cm in females)
Gender - male
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6
Q

What are some features on exam you would look for?

A
  • decreased breath sounds
  • prolonged expiration
  • wheeze
  • crackles
  • sats <90%
  • OSA
  • pul HTN (raised JVP, loud P2, peripheral oedema)
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7
Q

What are some investigations you can use pre-op? In what instances would you?

A

Spirometry
- lung resection, bypass, COPD/asthma, SOBOE/poor tolerance

not recommended routinely
CXR - >50 with thoracic surg
ABG - chronic hypercapneoa in oxygen dependent COPD or advanced restricted lung disease
CPET - lung resection surg
- preop FEV1, DLCO, VO2 max of 15ml/kg/min
- <10ml/kg/min = preop risk

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8
Q

What are the parameters you look at for spirometry?

A

FEV1/FVC ratio

  • <70 = obstructive
  • degree of obstruction - % FEV1 pred
  • bronchodilator response (>12% or 200mls)
  • FEV1 from 1.4L-1.8L

FEV1 <50% mortality of 5.6%

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9
Q

What are some management of COPD principles?

A

COPD X

  • confirm diagnosis (FEV1) with spirometry
  • optimise function - pulmonary rehab, physical activity, nutrition, educate, consider co-morbidities (OP, CVD, Lung ca, dep)
  • prevent deterioration
  • develop support and self management
  • manage exacerbations
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10
Q

How do you rank the severity of COPD? When should you add in medications?

A

% predicted FEV1

mild 60-80%

  • short acting relievers (SABA)
  • symptom relief (LABA/LAMA)

mod 40-60%

  • ICS/LABA combo
  • written action plan

severe <40%
- low dose theophylline, oxygen therapy, surgery, palliation

GOLD classification (based on post bronchodilator FEV/FVC ratio)

1 - FEV1 >80%
- influenza, SABA if needed

2 - mod FEV >50% < 80%
- LABA/LAMA

  1. severe FEV1 <50% but >30%
    - inhaled glucocorticosteroids if recurrent exacerbations
  2. very severe FEV1 <30%
    - long term O2
    - surgical therapies
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11
Q

How do you stratify asthma pre-op and does it alter management?

A
  • stable (similar to non asthmatics)
  • asthma meds 30 days prior (postpone non emerg surg)
  • consider staroid therapy in poorly controlled asthmatics (40mg once daily for 5 days or 8hrly 100mg IV hydrocort preop if ETT required)

airflow limitation, mucus hypersecretion and airway hyperresponsiveness predispose to complications.

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12
Q

What are the two modifiable risk factors to reduce post op pul complications in thoracic surgery? How do you modify these?

A

BMI and smoking

Smoking cessation >8 weeks prior to surgery

  • NRT
  • quit.org.au
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13
Q

What things can you do post op to reduce complications?

A
  1. Lung expansion modalities (CPAP, incensitve spirometry, deep breathing exercises)
  2. Sitting upright
  3. ANalgesia
  4. Avoid heavy sedatives
  5. VTE prophylaxis
  6. Early physio

Abdo:

  • selective NGt decompression
  • short acting neuromuscular blockage
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14
Q

What can be used as a predictor of post op pulmonary complications?

A

ARISCAT Score

  • age
  • preop spO2
  • resp function in last mth
  • preop anaemia
  • surgical incision
  • duration of surgery
  • emergency procedure
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15
Q

What is the post op O2 target in COPD patients?

A
  • CO2 retainers the target is reduced as CO2 is their ventilatory drive.
  • aim 88-92%
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16
Q

How can you categorise partly vs uncontrolled asthma?

A

3 or more of the following

  • daytime symptoms more than 2x/wk
  • limiting activities
  • nocturnal symptoms
  • needing a reliever >2x/wk
  • <80% predicted lung function
  • one or more exacerbations a year
17
Q

What is the stepwise management of asthma?

A
  • inhaled short acting beta 2 agonist (SABA)
  • regular preventor (ICS 200-800microg/day
  • LABA
  • if minimal response to LABA increase ICS if nil response stop LABA and increase ICS
  • uptitrate ICS to 2000microg/day
  • addition of leukotriene receptor antagonist, SR theophylline, beta 2 agonist
  • daily steroid tablet
18
Q

Which medications should be ceased periop in asthmatics?

A

Continue all regular medication including inhaled glucocorticoids

Cease theophylline the evening prior to surgery.

19
Q

What ventilation strategies should be used to reduce the rate of postop complications?

A

differentiation between normal and injured lung

Intraop

  • 6-8ml/kg tidal volume with minimal PEEP
  • PEEP reduces atelectasis and maintain O2 in non abdo surgery
  • high intraop FiO2 should be avoided to minimise atelectasis.

Postop

  • CPAP
  • intermittent positive pressure breathing
  • suctioning
  • chest physical therapy
  • deep breathing exercises
  • use of HFNO in obese patients
20
Q

What is the most frequently identified risk factor for postop complications?

A

COPD

- odds ratio for postop pul cx is higher than other patient factors

21
Q

A COPD patient in preop clinic produces large amounts of sputum at baseline with unilateral crackles, would you:

a) prescribe Aug DF for 5 days
b) do nothing
c) organise high res CT chest
d) 5 days of pred
e) refer to COPD outreach

A

c -
chronic suppuration with unilateral crackles may be focal bronchiectasis.
- chest physio and sputum expectoration are vital

22
Q

In an asthmatic which medication would you not consider prescribing?

a) salmeterol
b) salbutamol
c) budesonide
d) flutucasone/salmetrol
e) budesonide/eformoterol

A

a) salmeterol
- never give LABA without ICS
asthma is inflammatory and treatment of airway constriction alone for bronchospasm masks the underlying inflammation predisposing to acute/sudden asthma attacks