pulmonary defence mechanisms Flashcards
1
Q
where is 90% of airway mucus made from
A
glands
2
Q
where is 10% of airway mucus made from
A
epithelial (goblet) cells
3
Q
what does mucus contain
A
antimicrobial peptides and lyzozymes
4
Q
what defends the airspaces
A
alveolar macrophages (AM) crucial sentry cells
5
Q
what are AM cells a part of
A
the innate immune system
6
Q
what are the different parts of the airways where the three most identifiable reflexes originate from (3)
A
nasal cavities - sneeze
larynx and large airways - cough
vocal cords - expiration reflex
7
Q
what do coughs involve
A
bronchoconstriction
8
Q
whats reflect mucus secretion under
A
parasympathetic control - never voluntary
9
Q
what do sensory nerves respond to (5)
A
mechanosensitive cold heat/chemical heat inflammatory mediators stretch
