Pulmonary Flashcards
Rapid, deep labored breathing
Kussmaul breathing - DKA, Metabolic acidosis
Deep breathing alternating c apnea
Cheyne-Strokes breathing - HF, Brain damage
Cavitations on CXR
Infection - lung abscess, TB (Gohn focus)
Apical infiltrates, Fever, Chills, Dry cough
TB
Pleural thickening on CXR
Mesothelioma
Hilar mass on CXR
Lung CA
Eggshell pattern on CXR
Silicosis (sandblasters)
Diffuse ground glass appearance c/o pulmonary nodules on CXR
Infiltrative Lung Disease = Diffuse Pulmonary Lung Diseases
- Rheumatic = SLE, RA, SS
- Idiopathic = acute (<6 wks), chronic (> 6 mos)
- Drug induced = Bleomycin (macrolides), amiodoron, radiation
- Primary = sarcoidosis
- Exposure
- Asbestosis
- Hypersensitive pneumonitis
- Pneumocossis = Beryliosis, Silicosis, Black lung
Diffuse ground glass appearance c pulmonary nodules on CXR
Lung cancer
Reticular to nodular pattern on CXR
Black lung (Coal Miners)
Pleural based plaques on CXR
Asbestosis (ship Builders, building demolition)
Patchy fibrosis on CXR
Hypersensitivity pneumonitis (Farmer’s lung via biologic dusts from hay dust or mold spores or other agricultural products)
Granulomas & inflammation of alveoli, small bronchi, and sm bvs
Sarcoidosis
Dyspnea after surgery, travel (airplane), LE Fx. May have c/o calf pain also.
DVT/PE
Lung scan with perfusion defects
PE
Venous stasis, vessel wall injury, hypercoagulability
DVT/PE (Virchow’s triad)
Pediatric with barking cough, stridor
Viral croup (laryngotracheobronchitis); Tx w/ racemic epi & glucocorticosteroids if stridor at rest.
Pediatric wheezing
lower respiratory foreign body, Asthma
Drooling, sniffing position, tripod, toxic
Epiglottitis
Thumbprint sign
Epiglottitis
Steeple sign
Foreign Body, viral croup (laryngotracheobronchitis)
Inspiratory stridor
Foreign Body, viral croup (laryngotracheobronchitis)
Premature infant with respiratory distress
Hyaline Mb Disease
Preemie CXR w/ hypoexpansion (ATX), air bronchograms
Hyaline Mb Disease
Smoker, chronic productive cough. NO hemoptysis, wt. loss.
Brochitis (COPD) - Blue Bloater (decrease O2 = CYANOSIS, Pulm HTN, R CHF, EDEMA)
Smoker, DOE (dyspnea on exertion), cough
COPD
Hyperinflation on CXR, tear drop heart
Emphysema (COPD) - Pink Puffer (NORMAL O2, high CO2, increase AP diameter, PURSED LIPS)
Wheezing, prolonged expiration
Asthma
Airway edema with eosinophils, neutrophils, lymphocytes
Asthma
Fever, cough, sputum. Crackles, decreased breath sounds, dullness to percussion, +egophony, pectoriloquy. CXR - infiltrates or consolidation
Pneumonia (PNA)
>35yo with PNA. Rusty colored or yellow-green sputum. Acute onset F/C
Strep. Pneumonia
<35 yo, college students. Fever, cough, +/- sputum, chills, muscle aches
Mycoplasma pneumonia “walking pneumonia”
Bullous myringitis
Mycoplasma pneumonia; Bullous myringitis = middle ear infection “TM”
PNA c Smokers, COPD
H. influenza
PNA c DM, immunocomp, EtOH. Currant color sputum.
Klebsiella
PNA c water, late summer (AC), construction site. Diarrhea. Toxic looking
Legionella
PNA from Nursing homes, chronic care facility. Purulent sputum
S. aureus
PNA in HIV+, AIDS, Immunocompromised. Sx out of proportion to exam, elevated LDH and Hyper-hypoxia. Diffuse interstitial & alveolar infiltrates
Pneumocystis jerovecii (PJC); Tx = TMP-SMX Drug of choice
PNA & decreased mental status, poor dental hygiene, dentures, foul smelling sputum, bronchiectasis. Patchy infiltrates in dependant lung zones
Aspiration PNA
Pediatric with Hx recurrent lung infections, pancreatitis, reproductive problems, Failure to thrive (FTT)
Cystic fibrosis (Staph & Pseudomonal infections usually cause of death) (CF = autosomal recessive => thick & sticky fluids of mucus, sweat, and digestive juices => plug up tubes, ducts, and passageways => fatty stool, clubbing, etc…)
Sweat chloride test
Cystic fibrosis
Cystic fibrosis c PNA
Pseudomonas aueroginosa causative agent
< 2 days post-op c fever
Atelectasis
Stab wound, hyperresonance to percussion, decreased breath sounds, tympany
Pneumothorax (PTX)
Stab wound, dullness to percussion, decreased breath sounds.
Hemothorax (pleural effusion of blood accumulates in pleural cavity)
Tall, skinny, male, band student, acute onset one-sided chest pain, dyspnea
Spontaneous PTX
Stab wound to chest. Hypotension, tracheal shift
Tension PTX
Poor sleeping, obese, daytime fatigue & drowsy, snoring, HTN, PM wakening
Obstructive sleep apnea
s/p thoracic trauma. Multiple rib fractures. Chest wall moves in with inspiration, out c expiration.
Flail chest. Tx = pain control, incentive spirometry, pulmonary toilet, intubation
Asthma
Wheezing, reversible airway disorder. Samter’s triad: Asthma, ASA allergy, nasal polyp. Reduced FEV1 to FVC ratio
Acute Bronchitis
Viral, cough, negative CXR
Bronchiolitis
RSV (respiratory syncytial virus)
Epiglottitis
HIB (Haemophilus influenzae type B). Hot potato voice, sniffing position, drooling. X-ray: Thumb sign
Croup
Barking cough. X-ray: Steeple sign
Pertussis
Inspiratory whoop
Pneumonia
Productive cough, pleuritic chest pain, fever. lobar consolidation = bacteria. bilateral interstitial infiltrates = viral/pneumocystis
Tuberculosis
Fever, night sweats, hemoptysis. AFB/culture x 3 days. RIPE therapy. Screen with TNF inhibitors, immigration
Carcinoid Syndrome
Carcinoid tumor (rare) secretes chemicals into your bloodstream => Diarrhea, flushing, bronchospasm
Bronchiectasis
Cystic fibrosis. Tram lines. Obstructive pattern.
Obstructive lung dz
Obstructive pattern = inflamed + easily collapsible airways, obstruction to airflow, problems exhaling. Types = asthma, bronchiectasis, bronchitis and COPD
Emphysema
Smoking, alpha 1 antitrypsin deficiency, barrel chest, decreased DLCO and FEV1
Chronic Bronchitis
Smoking, decreased FEV1
Cystic Fibrosis
Autosomal recessive, infertility, sweat chloride test
Pulmonary embolism (PE)
Virchow’s triad (Venous stasis, vessel wall injury, hypercoagulability), sinus tachycardia, pleuritic chest pain, S1Q3T3, Westermark sign, Hampton hump
Asbestosis
- E
- CXR
3.
- E: Insulation, ship building
- CXR: thickened pleura and basilar lesions c DPLD
- Cause mesothelioma (lung ca)
Silicosis
- E
- CXR
- Tx
Silicosis pneumoconiosis
- E: Sandblasting, mines
- CXR: egg shell calcification c DPLD/pulmonary fibrosis
- Tx: steroids
Coal
- E
- CXR
- Tx
Black lung Pneumoconiosis
- E: Coal miners
- CXR: nodular opacities in the upper lung fields c DPLD
- Tx: steroids
Beryllium
- E
- CXR
- Tx
Berylliosis Pnemoconiosis
- E: Aerospace, electrical/nuclear plants
- CXR: diffuse infiltrates (DPLD) & hilar LAD
- Tx: steroids
Sarcoidosis
- CXR: Non caseating granulomas, erythema nodosum, bilateral hilar adenopathy
- Labs: elevated ACE (4x), elevated ESR
Pneumothorax
Smoking, family history, males tall/skinny, pleuritic chest pain
Rust-colored sputum - common in patients with splenectomy
S. Pneumoniae
Salmon colored sputum - MRSA treat with vancomycin
S. Aureus (think you can catch salmon with a “staph”)
Ventilator associated pneumonia patients become sick fast, treat c 2 abx
Pseudomonas
low Na+ (hyponatremia), GI sxs (diarrhea) and high fever
Legionella
Young people living in dorms, (+) cold agglutinins, bullous myringitis
Mycoplasma
Currant jelly sputum, drinkers, aspiration
Klebsiella (Clubbing - jello shots)
bird or bat droppings (caves, zoo, bird), Mississippi or Ohio river valley, mediastinal or hilar lymphadenopathy (looks like sarcoid)
Histoplasma capsulatum Chronic cavitary histoplasmosis is characterized by pulmonary lesions that are often apical and resemble cavitary TB. Manifestations are worsening cough and dyspnea, progressing eventually to disabling respiratory dysfunction. Dissemination does not occur. Treat: Amphotericin B
found in soil can disseminate and can cause meningitis
Cryptococcus Immunocompromised patients usually symptomatic Lumbar puncture for meningitis Treatment: Amphotericin B
Common in HIV-infected patients with a low CD4 count of less than 200, treat (and prophylax) with Bactrim
(PJP) Pneumocystis jiroveci - Formerly PCP Pneumonia
majority of cases in people c underlying illnesses such as tuberculosis or COPD, but c otherwise healthy immune systems
Pulmonary aspergillosis Treat: fluconazole or itraconazole
Look for this in a patient with non-remitting cough/bronchitis non-responsive to conventional treatments. Caused by fungal inhalation in western states.
Coccidioides (Valley Fever) Treat: fluconazole or itraconazole
Causes mediastinal or hilar lymphadenopathy (looks like sarcoidosis)
Histoplasma capsulatum
Transmission of vocal sounds through consolidation leads to the changes heard with
egophony Patients c pneumonia = (+) egophony
Consolidation would increase the transmission of vocal vibrations and manifest as
(+) tactile fremitus
Upper (apical) cavitary lesions
Active Tuberculosis
(+) cold agglutinins
Mycoplasma Pneumonia or Autoimmune hemolytic anemia
1st episode of cough and wheezing in a 4 month old
Bronchiolitis
+ PPD in a patient 1) HIV, 2)Rural mexico, 3)Nurse, 4)Traveler, 5)Homeless, 6)Soccer Mom
>5 mm (HIV) >10 mm (Rural Mexico, Nurse, Traveler, Homeless) >15 mm (Soccer mom)
Tuberculosis to spine
Potts disease
1) optic neuritis (red-green vision loss) “Eyes” 2) orange discoloration of body fluids
1) Ethambutol. 2)Rifampin
Patients on Isoniazid (INH) should take what supplement
Vitamin B6 (Pyridoxine) daily to prevent neuropathy
CXR => low grade CA seen as pedunculated sessile growth in central bronchi - Cutaneous flushing, diarrhea, wheezing and low BP
Carcinoid syndrome = Cutaneous flushing, diarrhea, wheezing and low blood pressure. This is the hallmark sign of carcinoid tumors which are GI tract cancers that have metastasized to the lungs
Patient will present with → cough and dyspnea for 6 days
Acute bronchitis
Patient will present as → first episode of wheezing in a child 12-24 months with findings of viral respiratory infection
Acute bronchiolitis
Patient will present with → sudden onset of high fever, respiratory distress, severe dysphagia, drooling and a muffled voice in an unvaccinated child. Thumbprint sign on lateral neck film
Acute epiglottitis
Patient will present as → a 2-year-old with barking cough and stridor. “Steeple sign” on PA neck X-Ray
Croup
Patient will present with → sudden onset of fever, chills, malaise, sore throat, headache coryza and myalgia (especially in the back and legs)
Influenza
Patient will present with → severe paroxysmal cough followed by an inspiratory high-pitched whoop, if untreated will develop a chronic cough lasting for weeks
Pertussis
Patient will present with → fever, dyspnea, tachycardia, tachypnea, cough +/- sputum
Bacterial Pneumonia
Patient will present with → 1 week history of hacking non-productive cough, low grade fever, malaise and myalgias. The chest x-ray reveals bilateral interstitial infiltrates and a cold agglutinin titer that is negative
Viral Pneumonia
Patient will present with → non-remitting cough/ bronchitis non-responsive to conventional treatments
Fungal Pneumonia
Patient will present as → a young person who you don’t know has HIV, bc of the pneumonia they have you become suspect. The radiograph shows diffuse interstitial or bilateral perihilar infiltrates
HIV-related Pneumonia
Patient will present with → 4-month-old with wheezing, cough and dyspnea
Respiratory syncytial virus (RSV) infection
Patient will present with → FEVER, hemoptysis, recent travel, NIGHT SWEATS, weight loss, shortness of breath, social contact with same symptoms
Tuberculosis
Patient will present with → haemoptysis, cough, focal wheezing or recurrent pneumonia. Carcinoid syndrome (the hallmark sign of cutaneous flushing, diarrhea, wheezing and low blood pressure) is actually quite rare.
Carcinoid tumors
Patient will present as → a previous smoker with a new or changing cough, weight loss, hemoptysis and hoarseness
Lung cancer
Patient will present → after having had a radiograph for something else and found to have a small < 3 cm pulmonary lesion, they are likely asymptomatic.
Pulmonary nodules
Patient will present with → foul breath, purulent sputum and hemoptysis along with a CXR demonstrating dilated and thickened airways with “plate-like” atelectasis (scarring)
Bronchiectasis
18/30 Patient will present with → foul breath, purulent sputum and hemoptysis along with a CXR demonstrating dilated and thickened airways with “plate-like” atelectasis (scarring) Bronchiectasis Patient will present with → a chronic cough that is productive of phlegm occurring on most days for 3 months of the year for 2 or more consecutive years without an otherwise-defined acute cause
Chronic bronchitis
Patient will present as → a young patient with a history of chronic lung disease, pancreatitis or infertility. May have clubbing of fingers CXR may reveal hyperinflation, mucus plugging and focal atelectasis. Labs will reveal an elevated quantitative sweat chloride test
Cystic fibrosis
Patient will present with → exertional dyspnea, minimal cough, quite lungs, thin, barrel chest. Chest X-ray will reveal flattened diaphragm, hyperinflation and small, thin appearing heart
Emphysema
Patient presents with → dyspnea, and a vague discomfort or sharp pain that worsens during inspiration. Physical exam reveals decreased tactile fremitus, dullness to percussion and diminished breath sounds over the effusion
Pleural effusion
Patient will present with → acute onset of ipsilateral chest pain and dyspnea. Physical findings will include decreased tactile fremitus, deviated trachea, hyperresonance, and diminished breath sounds.
Pneumothorax
Patient will present with → left parasternal systolic lift, a loud pulmonic component of S2 , functional tricuspid and pulmonic insufficiency murmurs, and later, distended jugular veins, hepatomegaly, and lower-extremity edema.
Cor pulmonale
Patient will present with → risk factors such as COCP use or recent surgery with a sudden onset of pleuritic chest pain, dyspnea, apprehension, cough, hemoptysis, and diaphoresis. Signs include tachycardia, tachypnea and crackles.
Pulmonary embolism
Patient will present with → dyspnea, chest pain, weakness, fatigue, edema, and ascites along with a narrow splitting of the second heart sound and a systolic ejection click.
Pulmonary hypertension
Patient will present with → insidious dry cough, dyspnea, fatigue, malaise, clubbing, inspiratory crackles
Idiopathic pulmonary fibrosis
Patient will present with → dyspnea, inspiratory crackles, clubbing of fingers, cyanosis and a work or exposure history that will provide you with the diagnosis
Pneumoconiosis
Patient will present as → a 30-year-old African American female with a cough, fever and generalized body aches. You order a CXR which shows bilateral hilar adenopathy
Sarcoidosis
Patient will present with → rapid onset of profound dyspnea occurring 12-24 hours after the precipitating event. Physical exam will show tachypnea, frothy pink or red sputum and diffuse crackles.
Acute respiratory distress syndrome
Patient will present as → a preterm infant with typical signs of respiratory distress shortly after birth
Foreign body aspiration
Who is the pneumococcal polysaccharide vaccine recommended for?
Young and old, sick, sickle cell, smokers, no spleen and liver disease
What bug is most likely to cause pneumonia in a patient
- c ETOH abuse
- c COPD
- c Cystic Fibrosis
- c Exposure to aerosolized water
- in Young adults
- in children < 1 yo
- in children < 2 yo
- mc CAP
- mc HCAP/ICU
- mc HCAI (infection)
- mc opportunistic infection in HIV pts
- c ETOH abuse = Klebsiella (Klub jello shots)
- c COPD = Haemophilus (Phyllis husband has COPD)
- c Cystic Fibrosis = Pseudomonas (Mona Lisa in chlorine tub)
- c Exposure to aerosolized water = Legionella
- in Young adults = Mycoplasma/ Chlamydia
- in children < 1 yo = RSV
- in children < 2 yo = Parainfluenza
- mc CAP = S. pneumoniiae > H. flu > Klebsiella, S. aureus, Legionella, Chlamydia, Mycoplasma
- mc HCAP = Pseudomonas > MRSA
- mc HCAI = UTI
- mc opportunistic infection in HIV pts = Pneumocystis jiroveci (formerly P. carinii)
What are the classic symptoms of TB?
Fever, night sweats, weight loss
What are Ghon complexes?
Represent healed infection = Calcified primary focus in the lungs
What is the historical landmark of TB?
Caseating granuloma that is AKA necrotizing granuloma
Side effects
- Rifampin
- Isoniazid
- Pyrazinamide
- Ethambutol
RIPE = all 4 for active TB
INH + B6 for 9 mo for latent TB
- Rifampin = red/orange discoloration and hepatitis
- Isoniazid = B6 deficiency, hepatitis, neuropathy
- Pyrazinamide = hyperuricemia => gout
- Ethambutol = optic neuritis
What radiographic finding is diagnostic for
- epiglottitis?
- croup?
- Thumbprint sign
- Steeple Sign
- What is the leading cause of cancer death?
- What is the most common cause of bronchogenic CA?
- What is the treatment of choice for Non-small cell CA?
- What is the leading cause of cancer death?
- Bronchogenic CA
- What is the most common cause of bronchogenic CA?
- Adenocarcinoma
- What is the treatment of choice for Non-small cell CA?
- Surgical resection
- What are the three components of asthma?
- What change in FEV1 after bronchodilation is supportive of the diagnosis of asthma?
- What is the most effective anti-inflammatory for chronic asthma?
- What medication must all asthma patients have regardless of the severity of their disease?
- What are the three components of asthma?
- Obstructive Airflow (Decrease FEV1 and Increase FVC), Hyperreactivity, Inflammation
- What change in FEV1 after bronchodilation is supportive of the diagnosis of asthma?
- 0.1
- What is the most effective anti-inflammatory for chronic asthma?
- Inhaled steroids
-
What medication must all asthma patients have regardless of the severity of their disease?
- short acting beta agonist (albuterol) as a rescue medication
- What is the most contributing cause of COPD?
- What deficiency leads to COPD?
- What is the single most important intervention in COPD
- What is superior to B agonists in achieving bronchodilation?
- What therapy is the only therapy that may alter the course of COPD?
- What are the main symptoms of cystic fibrosis?
- What is the most contributing cause of COPD?
- Smoking
- What deficiency leads to COPD?
- Alpha 1 antitrypsin
- What is the single most important intervention in COPD
- Smoking cessation
- What is superior to B agonists in achieving bronchodilation?
- Anticholinergics (ipratropium or tiotropium)
- What therapy is the only therapy that may alter the course of COPD?
- Supplemental oxygen
- What are the main symptoms of cystic fibrosis?
- Cough, excessive sputum, sinusitis, steatorrhea and ABD pain
What is the gold standard for identifying a pleural effusion?
Thoracentesis
What are the most common irritants used for pleurodesis?
Doxycycline and talc
A pleurodesis is a surgical procedure used to treat pleural effusion in mesothelioma patients. It is not a curative treatment, but rather an approach that is recommended when symptoms like chest pain and shortness of breath are causing discomfort.
What type of image reveals the presence of pneumothorax?
Expiratory CXR
- What are the risk factors for DVT/PE?
- What are the most common hypercoaguable states?
- What is the initial method for the diagnosis of PE?
- When is a negative D.Dimer helpful in ruling out PE?
- What are the risk factors for DVT/PE?
- Virchowís Triad: Damage, Stasis and hypercoaguable state
- What are the most common hypercoaguable states?
- High estrogen, cancer and genetics
- What is the initial method for the diagnosis of PE?
- Spiral CT
- When is a negative D.Dimer helpful in ruling out PE?
- With low pre-test probability
- What is the definitive test for PE?
- Pulmonary angiogram (V/Q study can be helpful too)
What physical findings are suggestive of pulmonary HTN?
Systolic ejection click and splitting/accentuation S2
What causes pneumoconoises?
Coal dust, silicate or other inert dusts
What is used to relieve chronic alveolitis in silicosis?
- What CXR findings are seen in asbestosis?
- What is the number one complication of asbestosis?
- What CXR findings are seen in asbestosis?
- Pleural based plaques c ground glass (DPLD)
- What is the number one complication of asbestosis?
- Mesothelioma
What disease is a multiorgan disease of idiopathic cause characterized by noncaseating granulomatous inflammation in affected organs?
Sarcoidosis
What is the main presentation of an aspirated foreign body?
Choking, coughing or unexplained wheezing or hemoptysis
- What is the most common cause of respiratory disease in a preterm infant?
- What can be used as prophylaxis or rescue in a patient with the established dz?
- What is the most common cause of respiratory disease in a preterm infant?
- Hyaline membrane disease
- What can be used as prophylaxis or rescue in a patient with the established Hyaline membrane disease?
- Exogenous surfactant
Pneumonia tx
- Fungal pneumonia
- Pneumocystis jiroveci (PJC)
- Histoplasma pneumonia
- Klebsiella pneumoniae
- Legionella pneumonia
- Pseudomonas pneumonia
- MRSA
- Mycoplasma
- Strep.pneumonia or non MRSA staph
- inpateitn ICU
- inpatient
- outpatient c comorbidities
- outpatient
- Fungal (immunocomp)
- Itraconazole or fluconazole
- PJC (HIV pts c low CD4 counts, or AIDS <200 CD4)
- Trimethoprim-sulfamethoxazole or pentamidine
- Histoplasma (inhlaled bat or bird droppings)
- Amphotericin B
- Klebsiella (ETOH, aspirations) => RUL abscess & currant jelly colored sputum
- Cephalosporins, Aminoglycosides, Fluoroquinolones
- Legionella (diarhea, water contamination, spa)
- Macrolides & Fluoroquinolones
- Pseudomonas - always 2 abx combo (post intubation, ventilator or hospital)
- Anti pseudomonal beta-lactam + antipseudomonal quinolone/aminoglycoside
- Antipseudomonal quinolone + aminoglycoside
- MRSA (salmon sputum)
- Vancomycin/linezolid + Levofloxacin/ciprofloxacin
- Mycoplasma (young, + cold agglutinins)
- Same as Strep ??
- Strep.pneumonia (lobar pneumonia, URI + rust colored sputum) or non MRSA staph (URI + salmon colored sputum)
- inpateitn ICU
- Beta-lactam + macrolide/fluoroquinolone
- inpatient
- Beta-lactam + macrolide
- outpatient c comorbidities
- Beta-lactam + macrolide/fluroquinolone/doxycyline
- outpatient
- macrolide/fluroquinolone/doxycyline
- inpateitn ICU
What must be considered with a young patient who has been exposed to rodent feces and has a “CHF like” presentation?
Hanta virus
- What type of Infant respiratory distress syndrome (IRDS) occurs in a near or full term infant?
- What type of Infant respiratory distress syndrome (IRDS) occurs in a preterm infant? (usually born before 30 weeks)
- What situations predispose an infant to developing type 2 IRDS?
- What situations predispose an infant to developing type 1 IRDS?
- What type of Infant respiratory distress syndrome (IRDS) occurs in a near or full term infant?
- Type 2 IRDS
- What type of Infant respiratory distress syndrome (IRDS) occurs in a preterm infant? (usually born before 30 weeks)
- Type 1 IRDS
- What situations predispose an infant to developing type 2 IRDS?
- C-section or diabetic mother
- What situations predispose an infant to developing type 1 IRDS?
- Incomplete lung development due to congenital malformation = pulmonary hypoplasia
Long term inflammation and eventual scarring after episodes of severe respiratory distress and mechanical ventilation?
Bronchopulmonary dysplasia
What antibiotic is most strongly associated with hypertrophic pyloric stenosis?
Clarithromycin (Note all macrolides can cause hypertrophic pyloric stenosis)
What is laryngotracheo-bronchitis also known as?
Croup
Where does the cancer associated with asbestosis tend to locate in the lung?
Mesothelioma locates to the pleural lining at the base of the lung
What is the Dx? Looks like CHF on chest X-ray but pulmonary wedge pressure in normal.
Acute respiratory distress syndrome (ARDS)
Pulmonary HTN Classes *list 5”
- Class 1 = Ventricular septal defect, Atrial septal defect, -Patent ductus arteriosus
- Class 2 = Mitral/Aortic stenosis, LV hypertrophy/falure
- Class 3 = COPD
- Class 4 = PE
- Class 5 = Sarcoidosis
Right heart failure caused by long term COPD history?
Cor pulmonale
Is chronic bronchitis or emphysema associated with an elevated hemoglobin?
chronic bronchitis
Pink Puffer?
Blue bloater?
- Pink Puffer? = Emphysema
- Blue bloater? = Chronic Bronchitis
- Only medication that improves morbidity and mortality in COPD?
- Agent of choice for COPD exacerbation?
- Oxygen
- Ipratropium
What is the likely Dx? Solitary pulmonary nodule of 2 cm in size found on chest X-ray incidentally.
Lung ca
What is a bloody pleural effusion concerning for?
malignancy
What criteria determine transudate from exudate?
Light’s criteria
- What is the most common type of lung cancer in smokers?
- Most aggressive lung cancer?
- What is the most common type of lung cancer in nonsmokers?
- What cancer is a patient with asbestos exposure at increased risk for.
- What is the most common type of lung cancer in smokers?
- Squamous cell
- Most aggressive lung cancer?
- Small cell
- What is the most common type of lung cancer in nonsmokers?
- Adenocarcinoma
- What cancer is a patient with asbestos exposure at increased risk for.
- Mesothelioma
What does a positive whisper pectoriloquy represent?
pulmonary consolidation
What is the most likely Dx? Smoker with hemoptysis weight loss and new DVT?
Lung ca
A “cinnamon breath smell” is associated with what pulmonary infection?”
Tuberculosis
- Where will older pulmonary lesions from tuberculosis be found?
- Where will newer pulmonary lesions from tuberculosis be found?
- What is the recommended treatment for a healthcare worker with a first time positive PPD?
- What is the sputum test for tuberculosis?
- Older = lower & middle lobe
- Newer = upper lobe
- Isoniazid (INH) for 6 months
- AFB smear and cultures
- What lab is elevated in PJP pneumonia?
- Tx PJP pna?
- LDH
- Trimethoprim-sulfamethoxazole or pentamidine
- What pneumonia is associated with air conditioning vents and spas?
- Most common ventilator associated bacterial infection?
- Young IV drug user with fever severe hypoxia and diffuse infiltrates on X-ray?
- Young patient after flu will get what infection?
- Legionella PNA
- Pseudomonas PNA
- PJP PNA
- S. aureus PNA
What pneumonia associated with diarrhea and low sodium levels?
Legionella
Flu + aspirin in children can cause what condition?
Reye syndrome
Flu can be treated with oseltamivir within how many hours of onset of symptoms?
48 hrs
Wet cough and foul smelling sputum in a child?
Bronchiectasis
Chronic aspiration in kids leads to plate like atelectasis on X-ray and what condition?
Bronchiectasis
How high does pulmonary pressure need to be to diagnose pulmonary HTN?
25 mmHg at rest
- What is the Dx? Patient worked with insulation. Chest X-ray shows thickened pleura and basilar lesions.
- What is the Dx? Pulmonary fibrosis in a patient who was a sandblaster. Chest X-ray shows egg shell calcifications.
- What is the Dx? Chronic dry cough dyspnea fatigue and clubbing. Chest X-ray shows fibrosis and CT chest shows honeycombing.
- What is the Dx? Chest X-ray shows bilateral hilar adenopathy and non caseating granulomas?
- What is the Dx? Patient worked with insulation. Chest X-ray shows thickened pleura and basilar lesions.
- Asbestosis
- What is the Dx? Pulmonary fibrosis in a patient who was a sandblaster. Chest X-ray shows egg shell calcifications.
- Silicosis
- What is the Dx? Chronic dry cough dyspnea fatigue and clubbing. Chest X-ray shows fibrosis and CT chest shows honeycombing.
- Idiopathic pulmonary fibrosis
- What is the Dx? Chest X-ray shows bilateral hilar adenopathy and non caseating granulomas?
- Sarcoidosis
Does patient with sarcoidosis tend to have high or low serum calcium levels?
High (hypercalcemia)
Gold standard test used to diagnose Pulmonary HTN?
Right heart cardiac catheterization
Treatment for acute respiratory distress syndrome (ARDS)?
Supportive care/ventilatory support - Find and treat underlying cause
Right sided heart failure due to pulmonary HTN?
Cor Pulmonale
Initial Treatment for pulmonary embolism?
Heparin
- What is the Dx? Young healthy female smoker on oral contraception with acute chest pain and SOB?
- What is the Dx? Thin young healthy male runner who develops acute onset of chest pain and dyspnea?
- Pulmonary embolus
- Spontaneous PTX
Initial treatment for all pneumothorax patients?
100% oxygen
What are the chest X-ray findings with acute respiratory distress syndrome (ARDS)?
Bilateral infiltrates/white out (may look like CHF)
- What type of COPD is associated with hyperventilation flat diaphragm on CXR and a normal Hgb/HCT?
- What are the two types of COPD?
- Emphysema
- Chronic bronchitis and emphysema
Most common cause of acute bronchitis?
Viral
- Types of asthma classifications?
- In a patients with asthma the FEV1 to FVC will be <______ ?
- Classes
- Intermittent => Mild persistent => Moderate persistent => Severe persistent
- FEV1 to FVC < 75% = diagnosis of asthma in pt with chronic wheezing/cough
- In a patient with malignancy is the pleural effusion transudative or exudative?
- In a patient with CHF is the pleural effusion transudative or exudative
- What conditions is a right sided pleural effusion often associated with?
- What is the main treatment for a pleural effusion?
- exudative
- transudative
- CHF or cirrhosis
- Thoracentesis
Name 3 types of non small cell (bronchogenic) cancers.
Squamous cell - Adenocarcinoma - Large cell
What is a Hallmark sign seen with carcinoid tumors?
Cutaneous Flushing
- Which virus can lead to pneumonia after URI and also often causes diarrheal illness/GI symptoms?
- Virus causing pneumonia after exposure to rodent feces (Western states)?
- Most common cause of viral pneumonia in adults?
- Organisms responsible for typical pneumonia?
- Organisms responsible for atypical pneumonia?
- Which virus can lead to pneumonia after URI and also often causes diarrheal illness/GI symptoms?
- Adenovirus
- Virus causing pneumonia after exposure to rodent feces (Western states)?
- Hantavirus
- Most common cause of viral pneumonia in adults?
- Influenza
- Name the organisms that cause typical pneumonia?
- S. pneumonia > H. flu > S. aureus > S. pyogenes (GAS)
- Organisms responsible for atypical pneumonia?
- Mycoplasma, Chlamydia, Legionella
- Should normal percussion over the lung fields sound dull or resonant?
- What does positive egophony on auscultation in a patient with pneumonia mean?
- Resonant
- When listening over the area of consolidation, patient will say “eee” and it sounds like “aaa”
What is the Dx? Previously healthy patient with abrupt onset of fever headache malaise occurring in the winter months.
Influenza
What condition is bronchiectasis often associated with?
What is the Dx? Previously healthy patient with abrupt onset of fever headache malaise occurring in the winter months.
Influenza
What condition is bronchiectasis often associated with?
Child with chronic persistent productive cough foul smelling sputum?
Bronchiectasis
- What is the cause of hyaline membrane disease in infants?
- Treatment for infant with Hyaline membrane disease (AKA: infant respiratory distress syndrome - IRDS)?
- Treatment to prevent Hyaline membrane disease in the newborn?
- Surfactant deficiency
- Respiratory support, Ventilatory support, Exogenous surfactant
- Give antenatal corticosteroids
- Organism that causes whooping cough?
- Childhood vaccine?
- Preferred treatment?
- Bordetella pertussis
- DTaP
- Clarithromycin or azithromycin (Macrolides)
- Steeple sign on a frontal chest X-ray showing tracheal narrowing & barking cough and stridor?
- Cause
- Croup
- Parainfluenza virus type 1
- Most common cause of acute bronchiolitis in an infant?
- How is it diagnosed?
- Respiratory syncytial virus (RSV)
- Analysis/culture of Respiratory secretions