Pulm Vasculature Flashcards
1
Q
WHO grouping (5) of Pulm HTN
A
- Pulmonary arterial HTN
- Left heart disease
- Lung disease / hypoxia (COPD, ILD)
- Chronic thromboemboli (PE)
- Misc (sarcoidosis)
2
Q
The mean pulmonary artery pressure must be >___mmHg at rest to dx pulm HTN.
(ON EXAM)**
A
>25mmHg
3
Q
Which world health group?
- Pulm Arterial HTN secondary to various disorders
- Diseases that localize directly to the pulm arteries leading to structural changes, smooth muscle hypertrophy, & endothelial dysfunction
A
Group 1
4
Q
Which World Health group?
- Schistosomiasis
- Drugs / toxins
- HIV
A
Group 1
5
Q
Which drugs will DEFINITELY cause pulmonary HTN?
A
Appetite suppressants (aminorex, fenfluramine, dexfenfluramine)
6
Q
Which drugs/toxins will POSSIBLY be risk factors for pulm arterial HTN? (PAH)
A
- amphetamines
- L-tryptophan
- meth
- cocaine
- St. John’s Wort
7
Q
What drug is:
- associated w/ development of persistent pulm HTN of the newborn when taken by pregnant mothers?
- associated w/ poor prognosis in those established w/ PAH?
A
SSRI
8
Q
Which group?
- Pulmonary venous HTN secondary to left heart disease
- Often referred to as “pulmonary venous HTN” or “post capillary pulm HTN”
A
Group 2
9
Q
Which group?
- Pulmonary HTN secondary to lung disease or hypoxemia
- Caused by advanced obstructive and restrictive lung disease (COPD, ILD, fibrosis, bronchiectasis)
A
Group 3
10
Q
- What is shown here?
- Which group?
A
- PE (bilateral) probably from DVT
- group 4 (clotting/emboli/thrombo)
11
Q
Which group?
- Pulm HTN secondary to chronic thromboembolic occlusion of proximal and distal pulm arteries
- This classification no longer includes pts w/ non-thrombotic occlusion, such as tumors/foreign objects
A
Group 4
12
Q
Group 5 is pulm arterial HTN secondary to what 4 things?
A
- Hematologic disorders
- Metabolic disorders
- Systemic disorders (sarcoidosis)
- Misc (tumor embolization***)
13
Q
- Which organization classified severity of pulm HTN?
- What 2 things is severity based on?
A
- NYHA, and modified by WHO
- Sxs & functional status
14
Q
Which class of NYHA severity?
- without limitation of physical activity
- no dyspnea, fatigue, CP, or near syncope w/ exertion
A
Class 1
15
Q
Which class of NYHA severity?
- Slight limitation of physical activity
- no sxs at rest, but ordinary physical activity causes dyspnea, fatigue, CP, or near syncope
A
Class 2
