Puberty Flashcards
Pubertal Timing
- 50% has to do with genetics and ethnicity
Puberty MOA
Females
- Estradiol levels progressively increase -> Maturation of female genital tract and breast development
Puberty MOA
Males
- Testosterone level increases x20 -> Correlates with physical stages of puberty and degrees of skeletal maturation
Physical Growth
Females
- Growth spurt begins nearly 2 years earlier in girls
- Peak height: between 11.5-12 years old
- 83-89% of total height attained: age 11
Physical Growth
Males
- Growth spurt lasts longer in boys than girls
- Peak height: between 13.5-14 years old
- Mass double between 10-17 years old
- 83-89% of total height attained: age 12
Psychosocial Development Early Adolescence (10-13 yo)
- Development of secondary sex characteristics
- Feel more comfortable with same sex
- Concrete thinking
Psychosocial Development Middle Adolescence (14-16 yo)
- Rapid pubertal growth/development subsides
- Emotions and wide mood swings
- Formal operations
- Abstract thinking
- Self-centered
- Peers determine standards for identification
Psychosocial Development Late Adolescence (17+ yo)
- Dating becomes intimate
- Abstract thinking
- Period of idealism
1st measurable sign of puberty in girls
- Height spurt
- 1st conspicuous sign is breast buds (8-11 yo)
1st measurable sign of puberty in boys
- Scrotal and testicular growth
Tanner Stages
Boys
Stage 1
- Infantile until puberty
- No true pubic hair, fine velus over the pubes
- Genitalia increase slightly in size over time, but little change to general appearance
Tanner Stages
Boys
Stage 2
- Scrotum begins to enlarge, reddening and change in skin texture
- Sparse growth of slightly pigmented hair, usually straight and only slightly curly, begins at either side of base of penis
Tanner Stages
Boys
Stage 3
- Penis increases in length, small increase in breadth
- Further growth of scrotum
- Hair spreads over pubis symphysis, considerably darker, coarse, and more curly
Tanner Stages
Boys
Stage 4
- Length and breadth of penis increase more, glans has developed
- Scrotum is further enlarged and scrotal skin becomes darker
- Hair is adult in character, covers area considerably smaller than most adults, no spread to medial surface of thighs
Tanner Stages
Boys
Stage 5
- Genitalia are adult in size/shape
- Hair is distributed in inverse triangle, spread to the top of medial thigh, but not above base of triangle
Tanner Stages
Girls
Stage 1
- No breast development
- No pubic hair
Tanner Stages
Girls
Stage 2
- Breast budding appears, some palpable breast tissue under nipple, areola is slightly enlarged
- Small amount of long pubic hair along vaginal lips
Tanner Stages
Girls
Stage 3
- Breast is more distinct, no separation between contours of two breasts
- Hair is darker, coarser, curlier, and spreads sparsely over pubic symphysis
Tanner Stages
Girls
Stage 4
- Breast further enlarged and greater contour distinction, nipple including areola forms a secondary mound on breast
- Hair is adult in type, area covered is smaller than most adults, no pubic hair on inside of thighs
Tanner Stages
Girls
Stage 5
- Breast is fully developed, distinct contours, areola has receded into general contour of breast
- Inverted triangle pattern of pubic hair
Adolescent Lipid Panels
- 9-11 yrs: Universal screen w/nonfasting non-HDL chol or fasting lipid screen
- 12-17 yrs: fasting lipid profile if FH newly positive, parent with dyslipidemia, any other RF
- 18-21 yrs: nonfasting non-HDL chol or fasting lipid profile
PP in genders
Male < age 9
Female < age 8
Diagnosing PP
- X-ray L hand to determine bone age
- Labs: LH, FSH, Estradiol/Testosterone levels
- If Central PP is Dx, get MRI of brain to r/o abnormalities of pituitary gland
Risks if Cryptorchidism is untreated
- Infertility
- Testicular malignancy
Cryptorchidism labs
- Infants between 2-6 months: measure LH, FSH, Inhibin B, and Test to determine if testes are present
- After 6 months: HCG stimulation test to confirm absence or presence of functional abdominal testes
Gynecomastia
- Occurs in 75% of normal pubertal boys, self-limiting
- More common in obese boys
- Typically resolves in 2 years
Turner Syndrome
Girls
- Short stature
- Infertile
- Webbed (extra skin) neck
- Swelling (lymphema) in hands/feet
- Heart Defects
- Kidney Problems
- Widely spaced nipples
- Brown spots on skin
Klinefelter Syndrome
Boys
- Tall stature
- Narrow chest
- Wider hips
- Female-type pubic hair pattern
- Breast development
- Osteoporosis
- Testicular atrophy