Puberty Flashcards
Tanner Stage 1
Prepubertal
Tanner Stage 2
Breast bud
Sparse hair growth along labia
Tanner Stage 3
No separation of breast contour
Coarser, more curled hair
Tanner Stage 4
Secondary mound above level of breast
Adult hair type, but covering smaller area
Tanner Stage 5
Mature stage
Precocious Puberty
Onset of puberty before Age 8 (> 2 standard deviations)
Central Precocious Puberty, labs to differentiate?
Caused by early maturation of HPO axis
Elevated LH and FSH
Peripheral Precocity, labs to differentiate
Caused by excess secretion of sex hormones
Suppressed FSH and LH
These DO NOT increase substantially with GnRh stimulation
Average Age of puberty in the US
Age 10-11
Order of puberty milestones
“Boobs, pubes, spurt, squirt”
Thelarche
Pubarche
Growth Spurt
Menarche
Define thelarche
breast developement
Define pubarche
Growth of pubic hair, usually a few months after breast development
Most common cause of precocious puberty
Idiopathic in about 80% of cases
Most common type of tumor to cause central precocious puberty
Hypothalamic Hamartomas
Precocious puberty with elevated FSH and LH?
Central precocious puberty