Puberty Flashcards

1
Q

Tanner Stage 1

A

Prepubertal

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2
Q

Tanner Stage 2

A

Breast bud
Sparse hair growth along labia

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3
Q

Tanner Stage 3

A

No separation of breast contour
Coarser, more curled hair

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4
Q

Tanner Stage 4

A

Secondary mound above level of breast

Adult hair type, but covering smaller area

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5
Q

Tanner Stage 5

A

Mature stage

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6
Q

Precocious Puberty

A

Onset of puberty before Age 8 (> 2 standard deviations)

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7
Q

Central Precocious Puberty, labs to differentiate?

A

Caused by early maturation of HPO axis

Elevated LH and FSH

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8
Q

Peripheral Precocity, labs to differentiate

A

Caused by excess secretion of sex hormones

Suppressed FSH and LH

These DO NOT increase substantially with GnRh stimulation

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9
Q

Average Age of puberty in the US

A

Age 10-11

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10
Q

Order of puberty milestones

A

“Boobs, pubes, spurt, squirt”

Thelarche
Pubarche
Growth Spurt
Menarche

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11
Q

Define thelarche

A

breast developement

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12
Q

Define pubarche

A

Growth of pubic hair, usually a few months after breast development

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13
Q

Most common cause of precocious puberty

A

Idiopathic in about 80% of cases

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14
Q

Most common type of tumor to cause central precocious puberty

A

Hypothalamic Hamartomas

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15
Q

Precocious puberty with elevated FSH and LH?

A

Central precocious puberty

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16
Q

Precocious puberty with decreased FSH and LH?

A

Peripheral Precocity

17
Q

Tumors that can cause peripheral precocity?

A

Granulosa cell tumors (elevated estrogen)

Sertoli/Leydig Cell tumors (can cause androgenization)

18
Q

Possible causes of peripheral precocity?

A

Ovarian Tumors
Primary Hypothyroidism
Exogenous chemicals/steroids
Adrenal Tumors
CAH
McCune-Albright-Syndrome

19
Q

Peripheral Precocious Puberty
Cafe-au-lait sponts
Fibrous dysplasia of bone

A

McCune-Albrite-Syndrome

20
Q

Treatment for central precocious puberty?

A

Usually GnRH agonist

21
Q
A

Tanner Stage 1

22
Q
A

Tanner Stage 2: Breast bud stage with elevation of breast and papilla, enlargement of areola

23
Q
A

Tanner Stage 3: Further enlargement of breast and areola: no separation of their contour

24
Q
A

Tanner Stage 4: Areola and papilla form a secondary mound above level of breast

25
Q
A

Tanner Stage 5: Mature stage, projection of papilla only, related to recession of areola