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Psychopharm Class > Psychotic Disorders Meds > Flashcards

Psychotic Disorders Meds Flashcards

1
Q

Brand name for chlorpromazine

A

Thorazine

CT

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2
Q

Is chlorpromazine high or low potency?

A

Low

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3
Q

Which med is indicated for hyperactive children who show excessive motor activity with accompanying conduct disorders?

A

chlorpromazine

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4
Q

Brand name for fluphenazine

A

Prolixin

fluphenazine Prolixin

FP

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5
Q

Is fluphenazine high or low potency?

A

high! more likely to cause EPS

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6
Q

How often would pt receive fluphenazine decanoate? (every ___ to ____ weeks)

A

every 2-3 weeks

to receive fluphenazine decanoate

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7
Q

Onset of fluphenazine decanoate is within ____ to ____ hours?

A

24 to 48

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8
Q

Brand name for haloperidol

A

Haldol

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9
Q

Is haloperidol high or low potency?

A

high! more likely to cause EPS

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10
Q

Which 1st gen antipsychotic is LOW potency?

A

chlorpromazine

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11
Q

Time for haloperidol to reach steady state?

A

1 week so pt may need to still take oral meds when starting the injection

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12
Q

Half life of haloperidol is ____ weeks?

A

3 weeks

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13
Q

What are the 2 mechanisms of action for atypical/2nd generation antipsychotics?

A

Mechanism of Action: D2 and 5HT (serotonin) receptor antagonism

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14
Q

Atypical antipsychotics have the clinical profile of equal positive symptom antipsychotic actions, but low _______ symptoms and less ________ compared to conventional antipsychotics

A

low extrapyramidal symptoms and less hyperprolactinemia

Atypical antipsychotics have the clinical profile of equal positive symptom antipsychotic actions, but low extrapyramidal symptoms and less hyperprolactinemia compared to conventional antipsychotics

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15
Q

Do atypical/2nd gen have improved efficacy over the first gens in treating the negative symptoms OR the positive symptoms of schizophrenia?

A

negative

improved efficacy over the FGAs in treating negative symptoms (e.g., flat affect, poverty of speech, lack of motivation and interest, poor grooming and hygiene) of schizophrenia

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16
Q

Brand name(s) for aripiprazole

A

Brand Name: Abilify, Abilify Maintena, Aristada

arip Abil

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17
Q

True or False: aripiprazole is not associated with any significant weight gain

A

True

aripiprazole is not associated with any significant weight gain

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18
Q

Brand name for asenapine

A

Saphris

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19
Q

Which antipsychotic is taken via sublingual tablet?

A

asenapine/Saphris

aSe Saph sublingual So many S’s

20
Q

True or False: For asenapine, pts should NOT eat or drink 10 mins following sublingual administration so the medication does not get washed into the stomach where it will not be absorbed

A

True

Patients should NOT eat or drink 10 mins following sublingual administration of asenapine/Saphris, so the medication does not get washed into the stomach where it will not be absorbed

21
Q

Brand names for clozapine

A

Clozaril, Leponex, Versacloz, Fazaclo

22
Q

Agranulocytosis (low white blood cell count) is a precaution for which antipsychotic?

A

Clozapine

23
Q

Patient’s clozapine therapy is interrupted when the ANC is less than ______ per μL?

A

1,000

patient’s clozapine therapy is interrupted when the ANC is less than 1,000/μL

24
Q

For clozapine-
Pts are required to get weekly ANC laboratory tests from initiation to _____ months. If blood tests are normal, patients are then required to have ANC levels tested every ______ weeks for the next 6 months, and _______ after 12 months.

A

6 months; two weeks; monthly

patients are required to get weekly ANC laboratory tests from initiation to 6 months. If blood tests are normal, patients are then required to have ANC levels tested every 2 weeks for the next 6 months, and monthly after 12 months.

25
Q

5 Signs of Neutropenia (infection)?

[from clozapine REMS slide]

A

Signs of Neutropenia (infection):

  1. Fever above 100.4 degrees
  2. Chills and Sweats
  3. Vomiting
  4. Diarrhea
  5. Shortness of Breath
26
Q

clozapine should not be combined with other drugs that can suppress _______ __________?

A

bone marrow

Should not combine clozapine with other drugs that can suppress bone marrow

27
Q

This harmful behavior can decrease clozapine levels

A

smoking!

28
Q

Brand names for iloperidone

A

Fanapt

iLo Fan
I love fans in summer?!

29
Q

Priapism (penis remains erect for hours w/o stimulation) is a precaution for which antipsychotic?

A

iloperidone/Fanapt

priapism is a precaution for iloperidone

iLo penis

30
Q

Brand names for lurasidone

A

Latuda

31
Q

Which antipsychotics should be taken with food?

A

lurasidone and ziprasidone

Lisa
cruZ loves food !!

32
Q

Brand names for risperidone

A

Risperdal, Consta, Trinza

33
Q

For risperidone/Consta injectable, must continue oral dosing for _____ weeks to allow injection to reach steady state

A

3 weeks

Must continue oral dosing for 3 weeks to allow injection to reach steady state, for risperidone/Consta

34
Q

Brand names for paliperidone

A

Invega; Invega Sustenna, Invega Trinza

pals don’t INVade during pandemic

paliperidone Invega

35
Q

What is the active metabolite of Risperdal?

A

paliperidone is the active metabolite of risperidone/Risperdal

36
Q

Brand names for olanzapine

A

Zyprexa, Zyprexa Relprevv., Symbyax (Olanzapine-Fluoxetine combo)

are the brand names for olanzapine

olanZ Zyprexa

37
Q

What is Symbyax made up (2)?

A

Symbyax = Olanzapine-Fluoxetine combo

38
Q

Brand name for quetiapine

A

Seroquel, Seroquel XR

Que Ser?

quetiapine Seroquel

39
Q

Brand name for ziprasidone

A

Geodon

zip to a GOOD GeOD adventure

ziprasidone Geodon

40
Q

Should not combine which antipsychotic with other drugs that can suppress bone marrow?

A

clozapine

41
Q

Which antipsychotic is known for its ability to cause akathisia (restlessness) and activation in patients?

A

aripiprazole/Abillify

Abilify’s thousand commercials always include being restless as a SE

42
Q

Patients should not eat or drink 10 mins following sublingual administration of this antipsychotic?

A

asenapine/Saphris

Patients should not eat or drink 10 mins following sublingual administration of asenapine/Saphris so the medication does not get washed into the stomach where it will not be absorbed

ase don’t eat you ass

43
Q

What are the 3 first gen antipsychotics?

A

chlorpromazine/Thorazine
fluphenazine/Prolixin
haloperidol/Haldol

44
Q

4 stages of Extrapyramidal Symptoms?

A

1) acute dystonia
2) Parkinsonism
3) akathisia
4) tardive dyskinesia

45
Q

Why do EPS occur?

A

bc of decrease in D2 in the nigrostrial pathway, and resulting acetylcholine imbalance

Psychopharm Class (3 decks)

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