Psychosis and schizophrenia Flashcards

1
Q

What is psychosis

A

State in which there is loss of contact with reality and includes

Delusions
Hallucinations
Formal thought disorder

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2
Q

What are positive symptoms of schizophrenia

A

Disorganised behaviour

Delusions

Thought disorder

Hallucinations

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3
Q

What are negative symptoms of schizophrenia

A
  • Avolition (lack of motivation)
  • POverty of speech
  • Social withdrawal
  • Reduced attention
  • Blunted affect
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4
Q

What are schizophrenia first rank symptoms

A
(ABCD)
Auditory hallucinatinos
Broadcasting of thought
Controlled thought 
Delusional perception
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5
Q

Organic causes of psychosis

A

Delirium- sepsis
Medication induced- corticosteroids, stimulants
Endocrine disorders- Cushing’s, hypothyroidism
Neurological disorder- temporal lobe epilepsy, multiple sclerosis, movement disorders, Wilson’s disease, Huntington’s disease

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6
Q

When is psychosis likely to be associated with schizophrenia

A

Symptoms present for >28 days
No organic cause
First rank symptoms present or persistent hallucinations and delusions

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7
Q

Psychiatric disorders which can present with psychosis

A

Schizoaffective disorder (first rank symptoms and mood symptoms)

Delusional disorder

Schizotypal disorder

Acute and transient psychotic disorder

Mood disorder (mania, severe depression)

Substance misuse (alcohol withdrawal, intoxication with stimulants, cannabis)

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8
Q

What is the prodrome

A

Period of time when the individual is gradually developing symptoms but has not yet met the criteria for diagnosis

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9
Q

symptoms of prodrome

A

Non-specific negative symptoms

Emotion distress/agitation without reason

Transient psychotic symptoms

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10
Q

Good prognostic factors for schizophrenia

A
Female 
Married 
Family history of affective disorder
Acute onset
Good premorbid personality 
Early treatment 
PRominent mood symptoms 
Good response to treatment
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11
Q

Poor prognostic factors for schizophrenia

A
FHx of schizophrenia 
High expressed emotion 
Substance misuse
PRominent negative symptoms 
Early onset
Lack of insight/non-compliance
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12
Q

What drug is used for treatment resistant schizophrenia

A

Clozapine

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13
Q

What are side effects of clozapine

How to monitor

A

Neutropenia and fatal agranulocytosis

Weekly FBC for 18 weeks then every 2 weeks for a year then every 4 weeks

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14
Q

Other side effects of clozapine

A
Hypersalivation
Cardiomyopathy
Myocarditis
Diabetes
Seizures
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15
Q

Psychological therapies for psychosis and schizophrenia

A

CBT

Family intervention Therapy

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16
Q

Social management of schizophrenia

A
Daytime activities/occupation.employment/leisure
Family
Accomodation
Benefits
Relationships
CUltural needs
Safeguarding