Psychosis Flashcards

1
Q

antipsychotic used in depression

A

flupentixole

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2
Q

what are the side effects of antipsychotics

A
galactorrhea 
behavioural effects
antimuscarinics (anti sludge) 
orthostatic hypotension (adrenoblockers)
H1 sedation and antimemeis
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3
Q

what opiod can be used in renal impairment

A

fentanyl

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4
Q

what is the cause of tardive dyskinesia

A

proliferation of dopamine receptors in the striatum

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5
Q

what is the cause of parkinonism symptoms

A

reversible block of nigrostriatal dopamine receptors

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6
Q

what are the behavioural effects of antipsychotics

A

apathy
reduced initiative
reduced aggresson

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7
Q

name some second generation antipsychotics

A
amisulpride
clozapine
olanzapine
risperidone
paliperidone
quietapine
aripiprazole
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8
Q

name some classical antipsychotics

A
chlorpromazine
fluphenazine
pipotiazine
haloperidol 
flupentixol
zuclopenthixol
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9
Q

what are the classes of antipsychotics

A

phenothiazines
butyrophenones
thioxanthines

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10
Q

what are the classes of atypical antipsychotics

A

benzamides

dibenzodiazepines

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11
Q

what is amisulpride

A

selective D2 and 3

benzamide

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12
Q

name a phenothiazine

A

chlorpromazine

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13
Q

what is the glutamate theory

A

glutamate and dopamine exert excitatory and inhibitory effects on gabergic neurons in the thalamus

too much dopamine or too little glutamate disables the gate allowing uninhibited sensory information to reach the cortex

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