Psychopharmacology, exam 2 Flashcards
Psychotropic meds do NOT cure patients with mental health disorders. So, if they don’t “cure” patients, what are they used for?
Psychotropic drugs help to manage the symptoms and manifestations of mental illness, so that a patient can function.
A patient is prescribed Lithium for her bipolar disorder. The patient says, “Thank god, I can finally cure my bipolar!” What is incorrect about this patients thinking? What is the lithium used for?
The psychotropic drug, Lithium, is not a cure for her illness. The lithium is used to help manage her bipolar symptoms so she can function more appropriately.
What is a big reason for non-compliance for patients taking psychotropic meds?
The patient states that they started feeling better, so they stopped taking their medication.
“Yeah, I stopped taking those pills yesterday. I started feelings better a week ago, so I figured I didn’t need them anymore.”
This sentence demonstrates a common statement regarding the patients what?
Non-compliance
What are 3 ways to ensure proper patient compliance?
-Encourage follow-up processes
-Make sure a patient understands the medication side effects
-Ensure proper administration of meds
“Start low and go slow.”
This sentence is in regard to what?
Medication dosage levels for children and the elderly.
What system is reduced in elderly patients that necessitates a lower dosage of medication?
Elderly patients have reduced metabolisms.
Why does “Start low and go slow” apply to children?
Children have underdeveloped metabolisms.
Most psychotropic meds have their effects at what synapse?
Neuronal synapse
Psychotropic meds having their effects at the neuronal synapse produces changes in what 2 things?
Neurotransmitter release and the receptors to which they bind.
Chemicals that convey information across the synaptic cleft, and are essential to human emotion and behavior are known as what?
Neurotransmitters
What do neurotransmitters convey their information across?
The synaptic cleft
Match these neurotransmitters with what they effect: Adrenaline, Noradrenaline, Dopamine, Serotonin
a.) Mood
b.) Concentration
c.) Pleasure
d.) Fight-or-flight
a.) Mood
-Serotonin
b.) Concentration
-Noradrenaline
c.) Pleasure
-Dopamine
d.) Fight-or-flight
-Adrenaline
Match these neurotransmitters with what they effect: Gaba, Acetylcholine, Glutamate, Endorphins
a.) Learning
b.) Calming
c.) Euphoria
d.) Memory
a.) Learning
-Acetylcholine
b.) Calming
-Gaba
c.) Euphoria
-Endorphins
d.) Memory
-Glutamate
What is the most common neurotransmitter? It is involved with learning and memory.
Glutamate is the most common neurotransmitter, and it is involved with learning and memory.
Which neurotransmitter regulates the development and creation of nerve contracts?
Glutamate
Produced in stressful situations. Increases heart rate and blood flow, leading to a physical boost and heightened awareness.
Which Neurotransmitter is this?
1.) Noradrenaline
2.) Serotonin
3.) Acetylcholine
4.) Adrenaline
5.) Glutamate
6.) Gaba
7.) Endorphins
8.) Dopamine
4.) Adrenaline is produced in stressful situations. Increases heart rate and blood flow, leading to a physical boost and heightened awareness.
Calms firing nerves in the central nervous system. High levels improve focus, low levels cause anxiety. Also contributes to motor control and vision.
Which neurotransmitter is this?
1.) Noradrenaline
2.) Serotonin
3.) Acetylcholine
4.) Adrenaline
5.) Glutamate
6.) Gaba
7.) Endorphins
8.) Dopamine
6.) Gaba calms firing nerves in the central nervous system. High levels improve focus, low levels cause anxiety. Also contributes to motor control and vision.
Positively effects attention and responding actions in the brain. Contracts blood vessels, increasing blood flow.
Which neurotransmitter is this?
1.) Noradrenaline
2.) Serotonin
3.) Acetylcholine
4.) Adrenaline
5.) Glutamate
6.) Gaba
7.) Endorphins
8.) Dopamine
1.) Noradrenaline positively affects attention and responding actions in the brain. It contracts blood vessels, increasing blood flow.
Involved in thought, learning, and memory. Activates muscle action in the body. Also associated with attention and awakening.
Which neurotransmitter is this?
1.) Noradrenaline
2.) Serotonin
3.) Acetylcholine
4.) Adrenaline
5.) Glutamate
6.) Gaba
7.) Endorphins
8.) Dopamine
3.) Acetylcholine is associated with thought, learning, and memory. It activates muscle action in the body. Also associated with attention and awakening
Feelings of pleasure, also addiction, movement, and motivation. People repeat behaviors that lead to it.
Which neurotransmitter is this?
1.) Noradrenaline
2.) Serotonin
3.) Acetylcholine
4.) Adrenaline
5.) Glutamate
6.) Gaba
7.) Endorphins
8.) Dopamine
8.) Dopamine releases feelings of pleasure, addiction, movement, and motivation. Repeated behaviors lead to more dopamine release.
Involved in learning and memory, regulates the development and creation of nerve contracts. The most common neurotransmitter.
Which neurotransmitter is this?
1.) Noradrenaline
2.) Serotonin
3.) Acetylcholine
4.) Adrenaline
5.) Glutamate
6.) Gaba
7.) Endorphins
8.) Dopamine
5.) Glutamate is involved in learning and memory, and it regulates the development and creation of nerve contracts. Glutamate is the most common neurotransmitter.
Contributes to well-being and happiness. Helps the sleep cycle and digestive system regulation. It is affected by exercise and light exposure.
Which neurotransmitter is this?
1.) Noradrenaline
2.) Serotonin
3.) Acetylcholine
4.) Adrenaline
5.) Glutamate
6.) Gaba
7.) Endorphins
8.) Dopamine
2.) Serotonin contributes to well-being and happiness. It helps with the sleep cycle and digestive system regulation. It is affected by exercise and light exposure.
Released during exercise, excitement, and sex. It produces feelings of well-being, bliss, and reduces pain.
Which neurotransmitter is this?
1.) Noradrenaline
2.) Serotonin
3.) Acetylcholine
4.) Adrenaline
5.) Glutamate
6.) Gaba
7.) Endorphins
8.) Dopamine
7.) Endorphins are released during exercise, excitement, and sex. They produce feelings of well-being, bliss and reduced pain.
Gaba and Glutamate are a part of what neurotransmitter classification?
Amino Acids
Norepinephrine, dopamine, and serotonin are a part of what neurotransmitter classification?
Monoamines
Endorphins are a part of what neurotransmitter classification?
Neuropeptides
Acetylcholine’s are a part of what neurotransmitter classification?
Cholinergic
Antipsychotics, Mood Stabilizers, Antidepressants, Anxiolytic/Antianxiety,
Sedatives/hypnotics, and Stimulants are all types of meds that affect mood and behavior. Because of this, what classification would these drugs be placed under?
Psychotropic drugs
Lithium is the most common stabilizer of a persons what?
Mood; Lithium is a Mood stabilizer.
What is an example of an anxiolytic/antianxiety drug?
Benzodiazepines
In addition to being used as an anxiolytic/antianxiety medication, Benzodiazepines are used for what?
Symptoms of alcohol withdrawal and perioperative sedations
What is a mental disorder that a stimulant may be used for?
ADHD
sedation, dizziness, confusion, hallucinations, dry mouth and urine retention are ALL possible side effects of what drug type?
a.) Anticholinergics
b.) Extrapyramidals
c.) Psychotropics
d.) Tardive Dyskinesia’s
e.) Antipsychotics
a.) Anticholynergic side effects are sedation, dizziness, confusion, hallucinations, dry mouth and urine retention
“Neuroleptics” is another word for what drug class?
Antipsychotics
“Extrapyramidal symptoms” are drug-induced movement disorders. What drug class is a big cause of Extrapyramidal symptoms?
Antipsychotics
Dystonia, Akathisia, Psuedoparkinsons, and Tardive Dyskinesia are all examples of what?
Extrapyramidal symptoms
Antipsychotics are a big cause of extrapyramidal symptoms. What does “extrapyramidal symptoms” mean?
Drug-induced movement disorders.
Involuntary muscle spasms in the face, legs, arms and neck that mainly effects men, and people under 25, are all markers of what type of extrapyramidal symptom?
a.) Tardive Dyskinesia
b.) Psuedoparkinsons
c.) Dystonia
d.) Akathisia
c.) Dystonia
Dystonia is involuntary muscle spasms in the face, legs, arms, and neck that mainly effect men and people under the age of 25
What extrapyramidal symptom is marked by motor restlessness and fidgeting in women, between 50-60 days after drug therapy starts?
a.) Psuedoparkinsons
b.) Akathisia
c.) Tardive Dyskinesia
d.) Dystonia
b.) Akathisia is marked by motor restlessness and fidgeting in women, 50-60 days after antipsychotic drug therapy starts.
What extrapyramidal symptom is marked by tremors, shuffling gait, drooling, and is found mainly in women, the elderly, and the dehydrated within the 1st week of drug therapy?
a.) Psuedoparkinsons
b.) Tremornergia
c.) Akathisia
d.) Tardive Dyskinesia
a.) Psuedoparkinsons is marked by tremors, a shuffling gait, drooling, and is mainly found in women, the elderly, and dehydrated patients in the 1st week of drug therapy.
What extrapyramidal symptom is marked by irreversible, bizarre tongue and facial movement?
a.) Psuedoparkinsons
b.) Dysphasia
c.) Akathisia
d.) Tardive Dyskinesia
d.) Tardive Dyskinesia is marked by irreversible tongue and face movements.
True or False:
Tardive Dyskinesia is an acute, sudden response to antipsychotic drug therapy that is irreversible.
False:
Tardive Dyskinesia is not sudden, and its warning signs are early, so the disease can be halted if the drug therapy is stopped BEFORE it becomes Tardive Dyskinesia.
What scale is used to assess for early warning signs of Tardive Dyskinesia?
The AIMS scale
Place the AIMS scale numbers in order of severity:
0, 1, 2, 3, 4
-None
-Minimal (Normal)
-Mild
-Moderate
-Severe
It goes in order:
0-None
1-Minimal (Normal)
2-Mild
3-Moderate
4-Severe
Which generation of meds is considered typical, and which is atypical?
-1st generation
-2nd generation
1st generation is typical.
2nd generation is atypical.
Tardive Dyskinesia is more common in typical antipsychotic drugs. Which generation is that?
1st generation
What two FDA-approved medications are used to treat tardive dyskinesia?
a.) Melatonin and Botox
d.) B6 and Valenzona
c.) Austido and Ingrezza
d.) Benadryl and Choco lax
c.) Austido and Ingrezza are approved to treat tardive dyskinesia.
Fun fact, Botox is used to treat it as well.
B6 and other vitamins have no evidence that they treat tardive dyskinesia, but some people think that they help.
Cogentin, Benadryl, Symmetrel, and Artane are used to treat what type of symptoms?
Extrapyramidal symptoms
What are the names of 4 drugs that some extrapyramidal symptoms are treated with?
-Cogentin
-Benadryl
-Symmetrel
-Artane
A rare, but fatal complication that is more common in 1st generation antipsychotic drugs, and requires ICU monitoring, is called what?
Neuroleptic Malignant syndrome.
What are the markers of Neuroleptic Malignant syndrome?
-Super high fever (107F)
-Muscle rigidity
-Tachycardia
-Tachypnea
What drugs are used to counteract Neuroleptic malignant syndrome?
Dantrolene Sodium drugs