Psychopharmacology

Question 1

Antipsychotics with low risk of hyperprolactinaemia

Answer 1

Aripiprazole
Olanzapine
Quetiapine
Clozapine

Question 2

Side-effects of clozapine

Answer 2

• Common: sedation, hypersalivation, dizziness, weight gain, constipation
• Uncommon: Muscle stiffness or tremor, flu-like symptoms, diabetes, tachycardia
• Rare but serious: Agranulocytosis, seizures, myocarditis, arrhythmias.

Question 3

Side-effects of lithium

Answer 3

• Common: Tremor, GI upset, polyuria, metallic taste, polydipsia.
• Uncommon: weight gain, hypothyroidism
• Rare but serious: Kidney problems, skin rash

Question 4

Lithium toxicity

Answer 4

• Blurred vision
• Vomiting
• Sleepiness
• Confusion
• Palpitations

Question 5

Side-effects of aripiprazole

Answer 5

• Common: Akathisia, GI upset, constipation, headache, insomnia, tremor, dizziness
• Rare but serious: seizures

Question 6

Side-effects of olanzapine

Answer 6

• Common: sleepiness, weight gain, postural dizziness, dry mouth, constipation, diabetes
• Rare: deranged LFTs, photosensitivity

Question 7

Side-effects of SSRIs

Answer 7

• Common: nausea, headache, insomnia, sexual dysfunction

- Rare: skin rashes

Question 8

Side-effects of procyclidine

Answer 8

• Common: dry mouth, constipation, blurred vision
• Rare: euphoria, hallucinations, urinary retention, rash
• CI: glaucoma, GI obstruction