Psychopharmacology Flashcards
half-life of a drug refers to
how long it takes to get rid of half of the drug from the body
potentiation
when one drug can enhance the second drug
synergism
when one drug can enhance the second drug significantly more than expected
when a medication is antagonistic it can do what to counter the effects of a second drug
reduce the effect of the second drug
acetylcholine
memory, learning and attention
epinephrine
secreted by adrenal gland and endocrine gland above kidney. For fight flight freeze response regulation
norepinephrine
wakefulness and alertness
dopamine
behavioural regulation, movement, learning, mood and attention.
Can be both excitatory and inhibitory
dopamin receptors can be activated by which drugs
cocaine and amphetamines
what types of medication are best for these symptoms ?
low energy, apathy, inability to feel pleasure, low motivation
Dopamine or noradrenogenic medications SNRIS
what types of medication are best for these symptoms ?
anxiety, agitation, obsessional symptoms, rumination, aggression, pronounced suicidality
SSRI’s best
hat types of symptoms would indicate that someone was a good candidate for anti-depressants
someone with vegetative symptoms eg. sleep disturbances, appetite disturbances, fatigue, decreased sex drive, total loss of ability to experience pleasure etc.
what do the guidelines say about drinking whilst on anti depressants
should not drink in excess of 1 per day
how long after treatments have resolved after pharmacological depression treatment can you stop taking medication?
6 months after symptoms resolve, unless client has hx of multiple dep episodes in lifetime consider ongoing
hypersomnia, significant weight gain, craving carbs, extreme fatigue are atypical symptoms of MDD commonly reported by which population
those with bipolar illnesses
what symptoms indicate risk of hypomania if reported for longer than 2 days
irritability
decreased need for sleep without daytime drowsiness
racing thoughts
rapid pressured speech
can you mix anti depressants with MAO inhhibitors
NO - FATAL
what medication may have dangerous interactions with st Johns Wort
ant depressants
a client tells you that they are taking SSRI’s and lithium what are you concerned about
SSRI’s increasing their lithium levels
what medication is suitable for rapid cycling of mania
Lamotrigine
what medication might be useful for mania with extreme agitation
antipsychotic or benzo
what medication might be useful for classic euphoric mania
lithium or divaloproex
What medication may be used for mixed mania symptoms
divaloproex
what medication might be used for depressive episodes
mood stabilisers eg.
lithium, lamotragine, quetiapine etc