Psychopharmacology

Question 1

What are the prescribing principles

Answer 1

1. Individual Clinical Presentation
2. Past response
3. Side effect profile
4. Patient Preference

Question 2

What the different types of dopaminergic pathways

Answer 2

1. Tuberoinfundibular
2. Nigrostriatal
3. Mesolimbic
4. Mesocortical

Question 3

Course of the mesoLimbic pathway and responsible symptoms if blocked

Answer 3

It runs from the Ventral Tegmental Area to Ventral Striatum. Positive symptoms of schizophrenia.

Question 4

Course of Mesocortical and responsible symptoms if blocked

Answer 4

VTA to pre-frontal cortex. Responsible for negative symptoms of schizophrenia

Question 5

Course of Nigrostrial and responsible symptoms if blocked

Answer 5

Substantia Nigra to caudate nucleus. Responsible for EPSE.

Question 6

Course of Tuberoinfundibular and responsible symptoms if blocked.

Answer 6

Hypthalamous to pituitary gland. Responsible for hyperprolactinemia.

Question 7

What is drug potency

Answer 7

Dose required to achieve therapeutic effect

Question 8

What is antipsychotic affinity

Answer 8

Action on dopamine receptors