Psychopharm Flashcards

1
Q

SSRI drugs

A

Fluoxetine
Sertraline
Citalopram
Escitalopram
Paroxetine

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2
Q

SSRI indications

A

MDD
GAD
SAD
PTSD
OCD
Panic Disorder

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3
Q

SSRI adverse effects

A

Insomnia
Nausea
Weight loss
Sexual dysfunction
Increased anxiety

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4
Q

TCA drugs

A

Amitriptyline
Imipiramine

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5
Q

The only indication for TCAs

A

MDD

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6
Q

Antidepressant drugs

A

Selective Serotonin Reuptake Inhibitors
Serotonin-Noradrenaline Reuptake Inhibitors
Tricyclic Antidepressants
Monoamine Oxidase Inhibitors

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7
Q

TCA moa

A

block:
- noradrenaline & serotonin reuptake
- muscarinic receptors
- histaminic receptors
- alpha-1 receptors

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8
Q

TCA adverse effects

A

arrythmias
cardiotoxicity
dry mouth
sedation
urinary retention
blurred vision
constipation
weight gain

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9
Q

Possible drug interaction with SSRIs

A

Warfarin
- SSRIs inhibit warfarin metabolism = more free warfarin = more bleeding

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10
Q

Why do patients on clozapine need regular WCC?

A

Risk of agranulocytosis

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11
Q

Common 2nd gen antipsychotic drug adverse effects

A
  • weight gain (quetiapine & olanzopine
  • agranulocytosis
  • QT prolongation
  • tardive dyskinesia
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12
Q

Common 1st gen antipsychotic drug adverse effects

A
  • EPSEs
  • hyperprolactinaemia
  • skin reactions
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