Psychopathology - Bio exp OCD Flashcards

1
Q

Studies

A

Karayiogou
Lewis
Schindler
Pigott
Szechtman
Max
Comer

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2
Q

Karayiogou

A

COMT gene assocaited with OCD
50% men
10% women

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3
Q

Lewis

A

37% parents of OCD have OCD
21% siblings of OCD have OCD

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4
Q

Schindler

A

Link between OCD + COMT
Rejected gendered differences

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5
Q

Pigott

A

SSRI - increase serotonin - limits OCD

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6
Q

Szechtman

A

Animals research
Higher dopamine = more stereotypes and compulsive behaviour

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7
Q

Max

A

Psychosurgery of Basal Ganglia = limits effects of OCD

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8
Q

Comer

A

Serotonin helps Caudate nuclei operate
Lower serotonin = more influence of OFC = more effects of OCD
(OFC = worry centre)

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