Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Psychiatry Clerkship > Psychiatry Clerkship > Flashcards

Psychiatry Clerkship Flashcards

1
Q

Selective serotonin reuptake inhibitors (SSRIs)

A

An adequate trial is considered 4-6 weeks SA: headache, GI disturbance, sexual dysfunction, increased bleeding (2/2 platelet dysfunction), increased risk of peptic ulcers (avoid NSAIDs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Venlafaxine (Effexor)

A

SNRI SA: diaphoresis, increased BP Not the best for hypertensive patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Duloxetine (Cymbalta)

A

SNRI FDA approved for pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Mirtazapine (Remeron)

A

Alpha2-adrenergic receptor antagonist Good for the elderly, increases appetite, sedating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tricyclic antidepressants (TCAs)

A

SA: sedation, weight gain, orthostatic hypotension, anticholinergic effects, prolonged QT interval Most lethal in overdose –> arrythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Monoamine oxidase inhibitors (MAOIs)

A

Used for refractory depression SA: hypertensive crisis when used with sympathomimetics or ingestion of tyramine-rich foods (wine, beer, aged cheeses, liver, smoked meats), orthostatic hypotension, serotonin syndrome if combined with other serotonergic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Lithium

A

Mood stabilizer Indicated for bipolar I Reduces suicide risk SA: weight gain, tremor, GI disturbance, fatigue, arrhythmias, seizures, goiter/hypothyroidism, leukocytosis, nephrogenic DI, polydipsia, alopecia, metallic taste Avoid in renal disease, heart disease, hyponatremia or diuretic use Check creatinine and TFTs before starting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Carbamazepine

A

Anticonvulsants Indicated for bipolar I, esp. rapid cycling or mixed features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Valproic acid

A

Anticonvulsants Indicated for bipolar I, esp. rapid cycling or mixed features Avoid in liver disease Monitor for thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Sertraline (Zoloft)

A

SSRI Good for atypical depression and MDD with psychotic features FDA approved for PTSD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Citalopram (Celexa)

A

SSRI FDA approved for MDD Good for depression in the elderly and for behavioral issues related to dementia Prolongs QTc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Prazosin

A

Alpha1-receptor antagonist Indicated for nightmares and hypervigilance a/w PTSD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Escitalopram (Lexapro)

A

SSRI Best tolerated SSRI FDA approved for MDD and GAD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Melatonin

A

Indicated for circadian rhythm sleep disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pramipexole

A

Dopamine agonist Indicated for Parkinson disease and restless leg syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Quetiapine (Seroquel)

A

Atypical antipsychotic SA: sedating Adjunct for depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Modafinil

A

Nonamphetamine Indicated for narcolepsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Risperidone

A

Atypical antipsychotic SA: hyperprolactinemia (sexual dysfunction, gynecomastia in men, amenorrhea, glactorrhea)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Aripiprazole (Abilify)

A

Atypical antipsychotic More weight neutral Good adjunct for depression SA: akathisia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Clozapine (Clozaril)

A

Atypical antipsychotic SA: agranulocytosis, seizures, myocarditis, orthostatic hypotension Very effective but reserved for patients who have failed at least 2 antipsychotic trials as need to regularly monitor CBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Olanzapine

A

Atypical antipsychotic SA: weight gain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Paliperidone (Invega)

A

Atypical antipsychotic Metabolite of risperidone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Lurasidone (Latuda)

A

Atypical antipsychotic Adjunct for bipolar, minimal effect on QTc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Ziprasidone

A

Atypical antipsychotic SA: prolongs QTc Minimal effect on weight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Treatment for acute mania

A

Antipsychotics (quick onset) Lithium Valproate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Lamotrigine

A

Anticonvulsant Indicated for bipolar depressive episodes SA: Stevens-Johnson syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Treatments for extrapyramidal symptoms

A

Acute dystonia –> benzotropine or diphenhydramine (IM) Akathisia –> reduction of antipsychotic dose + beta-blocker or benzodiazepine Parkinsonism –> benzotropine or amantadine Tardive dyskinesia –> no definitely treatment but clozapine may help

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Neuroleptic malignant syndrome

A

S&S: fever/hyperthermia, autonomic instability (tachycardia, labile BP, tachypnea, diaphoresis), muscle rigidity (lead-pipe), AMS, elevated CK Causes: antipsychotics, antiemetics, antiparkinson medication withdrawal Tx: stop the antipsychotic, supportive care (hydration, cooling), dantrolene or bromocriptine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Haloperidol

A

Typical antipsychotic, high potentcy SA: dystonia, akathisia, parkinsonism, tardive dyskinesia

30
Q

Serotonin syndrome

A

S&S: autonomic instability, AMS, hyperreflexia, myoclonus, increased bowel sounds Tx: stop medication, benzos for clonus, CCB for HTN, cyproheptadine

31
Q

Buspirone

A

Anxiolytic Indicated for generalized anxiety disorder

32
Q

Clomipramine

A

TCA (most serotonin selective) Can be used to treat obsessive-compulsive disorder but not first line

33
Q

Chlorpromazine

A

Typical antipsychotic

34
Q

Fluphenazine

A

Typical antipsychotic, high potentcy

35
Q

Perphenazine

A

Typical antipsychotic

36
Q

Atypical antipsychotics

A

Serotonin (5-HT2) and dopamine (D4 > D2) antagonists SA: HTN, hyperglycemia, weight gain, HLD

37
Q

What are the weight neutral atypical antipsychotics?

A

Aripiprazole Ziprasidone

38
Q

Which antipsychotics are good adjuncts for depression?

A

Aripiprazole Quetiapine

39
Q

Fluoxetine (Prozac)

A

SSRI Only SSRI FDA approved for bulimia Indicated for MDD, OCD, bulimia

40
Q

Alprazolam

A

Short-acting benzodiazepine Can cause seizures following abrupt discontinuation

41
Q

Paroxetine (Paxil)

A

SSRI FDA approved for PTSD Inhibits it’s own metabolism Short half-life –> requires taper

42
Q

Risk factors for obstructive sleep apnea

A

STOP BANG Snoring Tiredness during the day Observed apnea Pressure of blood BMI > 35 Age > 50 Neck circumference > 16 Gender of male

43
Q

Fluvoxamine (Luvox)

A

SSRI FDA approved for OCD and social phobia Interacts with nicotine

44
Q

Desvenlafaxine (Pristiq)

A

SNRI Active metabolite of venlafaxine

45
Q

Duloxetine (Cymbalta)

A

SNRI

46
Q

Serotonin discontinuation syndrome

A

S&S: dizziness, fatigue, headache, nausea, “electric like” shocks Highest risk is paroxetine

47
Q

What medication is contraindicated in eating disorders?

A

Bupropion because it lowers the seizure threshold

48
Q

Diagnostic tests for alcohol use disorder?

A

MCV –> macrocytosis GGT AST > ALT (not specific) Blood alcohol level (high levels without evidence of intoxication = tolerance) High HDL, low LDL (not specific)

49
Q

Buprenorphine

A

Opioid receptor partial agonist Used to treat opioid addiction

50
Q

Methadone

A

Opioid Used to help with opioid detox in people with opioid dependence

51
Q

Disulfiram

A

Inhibits aldehyde dehydrogenase –> patient feels ill if ethanol consumed Used to treat alcoholism in high-functioning alcoholics who desire long-term abstinence

52
Q

Treatment of catatonia

A

Benzodiazepines and/or ECT Avoid antipsychotics

53
Q

Lorazepam

A

Benzodiazepine

54
Q

Chlordiazepoxide

A

Very long-acting benzodiazepine Avoid in liver disease

55
Q

Bupropion

A

Norepinephrine and dopamine reuptake inhibitor (NDRI) Often added when partial response to SSRI or sexual side effects from SSRIs Can also aid in smoking cessation Avoid in patients with bulimia or seizures

56
Q

Nortryptyline

A

TCA

57
Q

Tranylcypromine

A

MAOI

58
Q

Flumazenil

A

Bensodiazepine antagonist Used to treat overdose

59
Q

Amitryptyline (Elavil)

A

TCA Most anticholinergic

60
Q

What medications are good for treating the depressed stage of bipolar disorder?

A

Atypical antipsychotics quetiapine and lurasidone

61
Q

Treatment for treatment-resistant or severe bipolar?

A

Lithium or valproate + atypial antipsychotic (quetiapine)

62
Q

Trazodone

A

Serotonin agonist and reuptake inhibitor Sedating SA: priapism

63
Q

Doxepin

A

TCA

64
Q

Imipramine

A

TCA

65
Q

Trimipramine

A

TCA

66
Q

Desipramine

A

TCA Least antichoinergic

67
Q

Isocaroxazid

A

MAOI

68
Q

Selegiline

A

MAOI

69
Q

Moclobemide

A

MAOI

70
Q

Pirlindole

A

MAOI

71
Q

Treating an MAOI-induced hypertensive crisis?

A

Stop medication, IV nitroprusside, clonidine

72
Q

In which psychiatric disorders is pharmacology the first line treatment?

A

ADHD Schizophrenia Bipolar disorder

Psychiatry Clerkship (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions