Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Psychiatry Clerkship > Psychiatry Clerkship > Flashcards

Psychiatry Clerkship Flashcards

1
Q

Selective serotonin reuptake inhibitors (SSRIs)

A

An adequate trial is considered 4-6 weeks SA: headache, GI disturbance, sexual dysfunction, increased bleeding (2/2 platelet dysfunction), increased risk of peptic ulcers (avoid NSAIDs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Venlafaxine (Effexor)

A

SNRI SA: diaphoresis, increased BP Not the best for hypertensive patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Duloxetine (Cymbalta)

A

SNRI FDA approved for pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Mirtazapine (Remeron)

A

Alpha2-adrenergic receptor antagonist Good for the elderly, increases appetite, sedating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tricyclic antidepressants (TCAs)

A

SA: sedation, weight gain, orthostatic hypotension, anticholinergic effects, prolonged QT interval Most lethal in overdose –> arrythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Monoamine oxidase inhibitors (MAOIs)

A

Used for refractory depression SA: hypertensive crisis when used with sympathomimetics or ingestion of tyramine-rich foods (wine, beer, aged cheeses, liver, smoked meats), orthostatic hypotension, serotonin syndrome if combined with other serotonergic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Lithium

A

Mood stabilizer Indicated for bipolar I Reduces suicide risk SA: weight gain, tremor, GI disturbance, fatigue, arrhythmias, seizures, goiter/hypothyroidism, leukocytosis, nephrogenic DI, polydipsia, alopecia, metallic taste Avoid in renal disease, heart disease, hyponatremia or diuretic use Check creatinine and TFTs before starting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Carbamazepine

A

Anticonvulsants Indicated for bipolar I, esp. rapid cycling or mixed features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Valproic acid

A

Anticonvulsants Indicated for bipolar I, esp. rapid cycling or mixed features Avoid in liver disease Monitor for thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Sertraline (Zoloft)

A

SSRI Good for atypical depression and MDD with psychotic features FDA approved for PTSD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Citalopram (Celexa)

A

SSRI FDA approved for MDD Good for depression in the elderly and for behavioral issues related to dementia Prolongs QTc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Prazosin

A

Alpha1-receptor antagonist Indicated for nightmares and hypervigilance a/w PTSD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Escitalopram (Lexapro)

A

SSRI Best tolerated SSRI FDA approved for MDD and GAD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Melatonin

A

Indicated for circadian rhythm sleep disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pramipexole

A

Dopamine agonist Indicated for Parkinson disease and restless leg syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Quetiapine (Seroquel)

A

Atypical antipsychotic SA: sedating Adjunct for depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Modafinil

A

Nonamphetamine Indicated for narcolepsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Risperidone

A

Atypical antipsychotic SA: hyperprolactinemia (sexual dysfunction, gynecomastia in men, amenorrhea, glactorrhea)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Aripiprazole (Abilify)

A

Atypical antipsychotic More weight neutral Good adjunct for depression SA: akathisia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Clozapine (Clozaril)

A

Atypical antipsychotic SA: agranulocytosis, seizures, myocarditis, orthostatic hypotension Very effective but reserved for patients who have failed at least 2 antipsychotic trials as need to regularly monitor CBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Olanzapine

A

Atypical antipsychotic SA: weight gain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Paliperidone (Invega)

A

Atypical antipsychotic Metabolite of risperidone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Lurasidone (Latuda)

A

Atypical antipsychotic Adjunct for bipolar, minimal effect on QTc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Ziprasidone

A

Atypical antipsychotic SA: prolongs QTc Minimal effect on weight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Treatment for acute mania
Antipsychotics (quick onset) Lithium Valproate
26
Lamotrigine
Anticonvulsant Indicated for bipolar depressive episodes SA: Stevens-Johnson syndrome
27
Treatments for extrapyramidal symptoms
Acute dystonia --\> benzotropine or diphenhydramine (IM) Akathisia --\> reduction of antipsychotic dose + beta-blocker or benzodiazepine Parkinsonism --\> benzotropine or amantadine Tardive dyskinesia --\> no definitely treatment but clozapine may help
28
Neuroleptic malignant syndrome
S&S: fever/hyperthermia, autonomic instability (tachycardia, labile BP, tachypnea, diaphoresis), muscle rigidity (lead-pipe), AMS, elevated CK Causes: antipsychotics, antiemetics, antiparkinson medication withdrawal Tx: stop the antipsychotic, supportive care (hydration, cooling), dantrolene or bromocriptine
29
Haloperidol
Typical antipsychotic, high potentcy SA: dystonia, akathisia, parkinsonism, tardive dyskinesia
30
Serotonin syndrome
S&S: autonomic instability, AMS, hyperreflexia, myoclonus, increased bowel sounds Tx: stop medication, benzos for clonus, CCB for HTN, cyproheptadine
31
Buspirone
Anxiolytic Indicated for generalized anxiety disorder
32
Clomipramine
TCA (most serotonin selective) Can be used to treat obsessive-compulsive disorder but not first line
33
Chlorpromazine
Typical antipsychotic
34
Fluphenazine
Typical antipsychotic, high potentcy
35
Perphenazine
Typical antipsychotic
36
Atypical antipsychotics
Serotonin (5-HT2) and dopamine (D4 \> D2) antagonists SA: HTN, hyperglycemia, weight gain, HLD
37
What are the weight neutral atypical antipsychotics?
Aripiprazole Ziprasidone
38
Which antipsychotics are good adjuncts for depression?
Aripiprazole Quetiapine
39
Fluoxetine (Prozac)
SSRI Only SSRI FDA approved for bulimia Indicated for MDD, OCD, bulimia
40
Alprazolam
Short-acting benzodiazepine Can cause seizures following abrupt discontinuation
41
Paroxetine (Paxil)
SSRI FDA approved for PTSD Inhibits it's own metabolism Short half-life --\> requires taper
42
Risk factors for obstructive sleep apnea
STOP BANG Snoring Tiredness during the day Observed apnea Pressure of blood BMI \> 35 Age \> 50 Neck circumference \> 16 Gender of male
43
Fluvoxamine (Luvox)
SSRI FDA approved for OCD and social phobia Interacts with nicotine
44
Desvenlafaxine (Pristiq)
SNRI Active metabolite of venlafaxine
45
Duloxetine (Cymbalta)
SNRI
46
Serotonin discontinuation syndrome
S&S: dizziness, fatigue, headache, nausea, "electric like" shocks Highest risk is paroxetine
47
What medication is contraindicated in eating disorders?
Bupropion because it lowers the seizure threshold
48
Diagnostic tests for alcohol use disorder?
MCV --\> macrocytosis GGT AST \> ALT (not specific) Blood alcohol level (high levels without evidence of intoxication = tolerance) High HDL, low LDL (not specific)
49
Buprenorphine
Opioid receptor partial agonist Used to treat opioid addiction
50
Methadone
Opioid Used to help with opioid detox in people with opioid dependence
51
Disulfiram
Inhibits aldehyde dehydrogenase --\> patient feels ill if ethanol consumed Used to treat alcoholism in high-functioning alcoholics who desire long-term abstinence
52
Treatment of catatonia
Benzodiazepines and/or ECT Avoid antipsychotics
53
Lorazepam
Benzodiazepine
54
Chlordiazepoxide
Very long-acting benzodiazepine Avoid in liver disease
55
Bupropion
Norepinephrine and dopamine reuptake inhibitor (NDRI) Often added when partial response to SSRI or sexual side effects from SSRIs Can also aid in smoking cessation Avoid in patients with bulimia or seizures
56
Nortryptyline
TCA
57
Tranylcypromine
MAOI
58
Flumazenil
Bensodiazepine antagonist Used to treat overdose
59
Amitryptyline (Elavil)
TCA Most anticholinergic
60
What medications are good for treating the depressed stage of bipolar disorder?
Atypical antipsychotics quetiapine and lurasidone
61
Treatment for treatment-resistant or severe bipolar?
Lithium or valproate + atypial antipsychotic (quetiapine)
62
Trazodone
Serotonin agonist and reuptake inhibitor Sedating SA: priapism
63
Doxepin
TCA
64
Imipramine
TCA
65
Trimipramine
TCA
66
Desipramine
TCA Least antichoinergic
67
Isocaroxazid
MAOI
68
Selegiline
MAOI
69
Moclobemide
MAOI
70
Pirlindole
MAOI
71
Treating an MAOI-induced hypertensive crisis?
Stop medication, IV nitroprusside, clonidine
72
In which psychiatric disorders is pharmacology the first line treatment?
ADHD Schizophrenia Bipolar disorder

Psychiatry Clerkship (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions