Psychiatry Flashcards
Mental State Examination parts
Appearance and behaviour Speech- RTV Mood and affect Thoughts Perceptions Insight Cognition Suicidal ideation
What is a delusion?
Firm, fixed false belief in something that is not in-keeping with cultural or societal views
What is an illusion
Real stimulus but false perception
Can be normal
Types of thoughts in MSE
Tangential Circumstantial Knight's move Clanging/ punning Blocking Perseveration Disorganised Neologism Loosened associations
Things to comment about appearance in MSE
Unkempt Clothing Behaviour- eye contact, expressions Motor symptoms- akathisia, depressive Body habitus Distracted
Types of hallucination
Auditory Visual Gustatory Olfactory Somatic Tactile
One unit of alcohol in grams
8g of absolute alcohol
Alcohol detoxification withdrawal symptoms/signs
Seizures after around 37 hours
Delirium tremens after around 72 hours
1-4 days Nausea and vomiting Tremor Sweats Anxiety Disturbed sleep Hypertension Tachycardia
2+ days Confusion Extreme agitation Dehydration Delirium tremens
Symptoms/signs of delirium tremens
Severe confusion Agitated behaviour Extreme hyperactivity Global dysfunction LOC Hallucinations Sleep disturbance Fever HTN Tachycardia Hyperhidrosis Dehydration
Scoring system used in alcohol withdrawal
CIWA-Ar
10 or more then diazepam
Three scores less than 10- stop diazepam
ICD-10 definition of dependence syndrome
Compulsion to take it and difficulty controlling this
Physiological withdrawal state
Evidence of tolerance
Neglect of alternative pleasures
Continuation of substances despite harming consequences
Drugs for alcohol withdrawal
Disulfiram- causes acute insensitivity reaction to ethanol- inhibits acetaldehyde dehydrogenase
Naltrexone- opioid receptor antagonist, reduces cravings and euphoria
Acamprosate- GABA analogue, good for maintenance of alcohol abstinence
Adverse effects of lithium
Nausea and vomiting
Diarrhoea
Fine tremor
Nephrotoxic- diabetes insipidus and secondary polyuria
Hypothyroid secondary to thyroid enlargement
IIH
Weight gain
Leucocytosis
Hyperparathyroidism and secondary hypercalcaemia
When should lithium levels be monitored?
12 hours post-dose
Weekly after starting or changing dose, until stable levels
Checked every 3 months
Thyroid and renal function assessed every 6 months
Features of lithium toxicity
Coarse tremor Hyperreflexia Acute confusion Polyuria Seizure Coma
Lithium toxicity may be precipitated by
Dehydration
Renal failure
Diuretics, ACE-i, ARBs, NSAIDs and metronidazole
Lithium toxicity management
If low levels then alkalisation of urine may help to excrete more
Fluid resuscitation
If extreme then haemodialysis may be indicated
Side effect of Mirtazapine
Increase in appetite
Conversion disorder
Typically motor or sensory options
Patient doesn’t consciously feign symptoms or seek material gain
Second generation anti-psychotics
Clozapine Olanzapine Risperidone Quetiapine Amisulpride Aripiprazole
Monitoring of what with clozapine use is extremely important
FBC
Risk of agranulocytosis/ neutropenia
Should only be used in patients resistant to other treatment
Dose adjustment if starting or stopping smoking
What is bulimia nervosa?
Characterised by episodes of uncontrollable binge eating followed by purgative behaviours to prevent weight gain (such as self-induced vomiting, laxative use, diuretics, exercise)
First generation antipsychotics and their side effects
Haloperidol, chlorpromazine
Extrapyramidal side effects and hyperprolactinaemia are common
Examples of typical antipsychotic extra-pyramidal side effects
Parkinsonism
Acute dystonia- sustained muscle contraction (managed with procyclidine)
Akathisia
Tardive dyskinesia
Best SSRI post-MI
Sertraline
Which SSRI is most likely to cause a prolonged QT?
Citalopram
SSRI side effects
Most common is GI
Increased risk of GI bleed (PPI if also on NSAID)
Hyponatraemia
Management of Generalised Anxiety Disorder
Education about GAD and active monitoring
Low intensity psychological interventions- self help or psychoeducational groups
CBT or drug treatment
Specialist input
PTSD management (symptoms for 4 weeks)
Watchful waiting if <4 weeks
Trauma-focused CBT or Eye Movement Desensitisation and Reprocessing
Venlafaxine or SSRI if pharmacological is necessary
Anti-muscarinic side effects of TCAs
Blurred vision Dry mouth Drowsiness Constipation Urinary retention QT lengthening
Schneider’s first rank symptoms of Schizophrenia
Auditory hallucinations- thought echo, two or more voices discussing in the third person, voices commenting on patients behaviour (running commentary)
Thought disorder- Insertion, withdrawal, broadcasting
Passivity phenomena- body activities being controlled externally, experiences are imposed on the individual- eg actions, impulses or feelings
Delusional perceptions- a two stage process- delusional insight from a normal stimulus
How long should SSRIs be prescribed for minimum
6 months- prevents relapse into depression
Indications for ECT
Severe depression, catatonic schizophrenia and severe mania
Side effects of ECT
Headache, nausea, memory impairment and arrhythmias
Very few long term effects noted
Definition of hypomania
Decreased or increased function for 4 days
Elevated mood or irritability
Definition of mania
Severe functional impairment or psychotic symptoms (delusions of grandeur or hallucinations) for 7 days or more
Definition of chronic insomnia
Trouble falling asleep or staying asleep at least 3 nights a week for at least 3 months