Psychiatry Flashcards
What are the 3 core symptoms of depression
Low mood
Lack of pleasure (Anhedonia)
Loss of energy
Name other symptoms of depression
Low mood Anhedonia/lack in pleasure Reduced libido Weight change Insomnia Psychomotor agitation or retardation Feelings of worthlessness, guilt Reduced concentration span, indecisiveness Recurrent thoughts of death or suicide
Name the somatic symptoms of depressive illness
Loss of emotional reactivity Diurnal mood variation Anhedonia Early morning waking Psychomotor agitation or retardation Loss of appetite or weight Loss of libido
What psychotic symptoms can manifest in depression?
Delusions - poverty, personal inadequacy, nihilistic, responsibility for natural disasters, wars, accidents
Hallucinations - auditory: accusatory, defamatory voices, cries for help, screaming
Olfactory: bad smells, rotten flesh, food, faeces
Visual: tormentors, demons, the devil, dead bodies, scenes of death, torture
What other subtypes of depressive disorder are there? (Not including major depressive disorder)
Atypical depression
Postnatal depression
Seasonal affective disorder
Premenstrual dysphoric disorder
What types of antidepressants are there?
Selective serotonin re-uptake inhibitors
Monoamine oxidase inhibitors
Tricyclic antidepressants
Why are SSRIs more commonly used?
Side effects better tolerated
Less dangerous if overdosed
Name 3 SSRIs and side effects
Sertraline
Citalopram
Fluoxetine
Nausea, diarrhoea, GI upset, headache, agitation, anxiety
Name 2 TCAs and their side effects and contraindications
Clomipramine hydrochloride
Imipramine hydrochloride
Dry mouth, blurred vision, drowsiness, constipation, urinary retention
Contraindications: acute MI, heart block, arrhythmia, IHD, pregnancy, severe liber disease
Name 3 MAOIs and side effects
Tranylcypromine
Phenelzine
Isocarboxazid
Risk of hypertensive crisis - avoid foods high in tyramine - cheese, marmite, avocados
Hepatotoxicity, insomnia, anxiety, appetite suppression, weight gain
Define illusion
A false perception of a detectable stimulus (something is there by misinterpreted)
Define hallucination and give different types
A sensory experience involving the apparent perception of something not present
Auditory - hearing a voice speak ones thoughts out loud, hearing a voice narrating ones actions, hearing 2+ voices arguing
Olfactory
Visual - associated with organic disorders of brain and drug/alcohol intoxication
Lilliputian - things/people/animals smaller than would be in real life
Extra campine - beyond possible sensory modality eg seeing someone stood behind
Hypnagogic/hypnopompic - occur falling asleep or waking up
Elemental - flashes of light or unstructured noises
Reflex - hallucinations in one modality after experiencing a normal stimulus in another modality
What is an over-valued idea?
Non delusional, non obsessional abnormal belief.
It is acceptable and comprehensible but is preoccupying and comes to dominate their thinking and behaviour.
Held with rigidity but can be changed.
Concern over physical appearance in dysmorphophobia
Concern over weight in anorexia nervosa
Concern over personal rights in paranoid PD
What is a delusion and give examples
A pathological belief which is held with absolute subjective certainty and cannot be rationalised away, requires no external proof and may be held in face of contradictory evidence. Has personal significance and importance to the individual concerned.
Persecutory - external agency will cause you harm
Grandiose - believe you are super
Self referential - constructing links between random things
Nihilistic - am dead, everything dead, world no longer exists, smells rotting
Misidentification - replaced by imposter
Religious
Hypochondriac - believe they have illness
Guilt
What is a delusional perception?
A true perception to which a patient attributes a false meaning - schizophrenic trait
What is a thought disorder and give examples
Thought disorder - any change in form or content of thought
Thought alienation - patient feels that their own thoughts are no longer in their control (Sx of psychosis)
Thought insertion - delusional belief that thoughts are being placed in the patient’s own head by external agent
Thought withdrawal - thoughts are disappearing by external agent
Thought broadcast - thoughts are accessible directly to others, broadcast to everyone around you
Thought echo - experience of auditory hallucination in which the context is individuals own thoughts - an internalised running commentary (1st rank Sx schizophrenia)
Thought block - patient experiences a sudden break in chain of thought. Thought, sentence, idea stops even if someone reminds you what it was about.
What is concrete thinking?
The loss of ability to understand abstract concepts and metaphorical ideas leading to a strictly literal form of speech and inability to comprehend allusive language
What is loosening of association?
A lack of meaningful connection between sequential ideas so hard to follow in conversation. Nothing links but they do make sense