Psychiatry Flashcards

1
Q

PTSD diagnostic criteria

A

1) Exposure to actual/threatened death, serious injury, or sexual violation in >=1 of the following ways
2) >=1 intrusive symptoms
3) >=1 avoidance symptoms
4) >=2 negative mood symptoms/dissociative symptoms
5) >=2 arousal/reactivity symptoms

  • duration of above symptoms > 1 month
  • clinically significant distress/impairment
  • NO from substances NO from another medical condition
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2
Q

Acute Stress Disorder diagnostic criteria

A

1) Exposure to actual/threatened death, serious injury, or sexual violation in >=1 of the following ways
2) >=9 of the symptoms from any of the 5 categories: intrusive, negative mood, dissociative, avoidance, arousal
3) duration of symptoms for at least 3 days to 1 month after the trauma
4) clinically significant distress/impairment
5) NO from substance NO from another medical condition

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3
Q

Adjustment Disorder diagnostic criteria

A

1) Within 3 months of stressor, emotional/behavioral response
2) clinically significant behaviors/ symptoms as evident by >=1 of the following :
- marked distress out of proportion to severity of the stressor
- significant impairment
3) Does not meet criteria for another mental disorder
4) Does not represent bereavement
5) Once stressor or its consequence are terminated, symptoms do NOT persist more than 6 months

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4
Q

What are the specify of Adjustment Disorder ?

A

w/ depressed mood
w/ anxiety
w/ disturbance of conduct

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5
Q

Treatment for PTSD

A

** Therapy: CBT - early intervention is vital
** Reduce caffeine, alcohol, stress
** Medication: fluoxetine, paroxetine, sertraline, venlafaxine
- Second line: mirtazapine
- For nightmares: Trazodone (50-200mg) or Prazosin (1-15mg po QHS)
- continue > 8 weeks
- consider second generation atypical antipsychotics
or anticonvulsants

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6
Q

ADHD diagnostic criteria (DSM V)

A

> > Either (1) or (2): in adults only need 5 of 9 Sx

(1) >= 6 symptoms of inattention, persisted >= 6 mo that is inconsistent with developmental level, negatively impacts social, academic, occupational
(2) >= 6 symptoms of hyperactivity-impulsivity, persisted >=6 mo to a degree that is maladaptive and inconsistent with the developmental level

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7
Q

symptoms of eating disoder

A

Cardiorespiratory: palpitation, cp, sob, arrhythmia, edema, MVP

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8
Q

Diagnostic criteria of alcohol withdrawal syndrome

A

1) decreased EtOH use that has been heavy/ prolonged
2) has > or = 2 of the the following:
- autonomic hyperactivity (sweating,
tachycardia) ;
- increased hand tremor;
- insomnia;
- nausea or vomiting;
- transient visual, tactile, auditory hallucinations or illusions;
- psychomotor agitation;
- anxiety;
- tonic-clonic seizures
3) symptoms cause distress/impairment

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9
Q

contraindications to outpatient treatment of alcohol withdrawal syndrome

A

Abnormal laboratory results
Absence of a support network
Acute illness
High risk of delirium tremens
History of a withdrawal seizure
Long-term intake of large amounts of alcohol
Poorly controlled chronic medical conditions (e.g., diabetes mellitus, chronic obstructive pulmonary disease, congestive heart failure)
Serious psychiatric conditions (e.g., suicidal ideation, psychosis)
Severe alcohol withdrawal symptoms
Urine drug screen positive for other substances

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10
Q

symptoms of delirium tremens

A

severe hyperadrenergic state (i.e., hyperthermia, diaphoresis, tachypnea, tachycardia) characterized by disorientation, impaired attention and consciousness,
and visual and/or auditory hallucinations

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11
Q

Timing of alcohol withdrawal syndrome

A

12-24hrs after the last drink: tachycardia, tremors, anorexia, insomnia

24-72hrs: generalized seizures

3-5d: delirium tremens –> disorientation, fever, hallucinations

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12
Q

When to consider report to MOT of driving

A
  • drinking + driving
  • drove while intoxicated
  • withdrawal seizure
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13
Q

1st meds to treat alcohol withdrawal as outpatient

A

anticonvulsants (not able to prevent seizure or delirium tremens)
- carbamazepine, gabapentin

Alpha-adrenergic agonist
- clonidine (s/e: Hypotension, dry mouth,
dizziness, constipation,
sedation)

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14
Q

contraindications to use Naltrexone or Acamprosate to treat EtOH dependence

A

Naltraxone:

  • liver failure
  • ongoing opioid use b/c risk of acute withdrawal
  • can be used if pt will abstain from opioid
  • ** use for abstinence OR reduction
  • ** check LFTs 1,3,6 mos

Acamprosate

  • severe renal impairment
    • use ONLY for abstinence, does NOT reduce heavy drinking
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15
Q

complications of Alcohol Use Disorder

A
  • CNS:
    Wernicke encephalopathy (decreased thiamine=nystagmus, CNVI, ataxia, confusion)
    Korsakoff psychosis
    dementia
  • CVS:
    HTN
    cardiomyopathy
    AFib
- GI
cirrhosis 
PUD 
gastritis 
pancreatitis 
carcinoma 
  • Psycho
    depression
    anxiety
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16
Q

classes of ADHD medications

A

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  • Amphetamine-based: Adderall, Vyvanse
  • Methylphenidate-based: Biphentin, Concerta, Ritalin (short acting)

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  • SNRI (selective norepinephrine reuptake inhibitor): Atomoxetine (brand: Strattera)
  • Selective alpha-2a adrenergic receptor agonist: Guanfacine XR (Intuniv XR)
17
Q

contraindications of ADHD medications

A

For psychostimulants and Atomoxetine:

 Treatment with MAO inhibitors and for up to 14 days after discontinuation

 Symptomatic cardiovascular disease

 Glaucoma

 Advanced arteriosclerosis

 Untreated hyperthyroidism

 Acute psychiatric conditions such as mania or psychosis

 Moderate to severe hypertension

Extra caution for Atomoxetine:
 Asthma

18
Q

s/e of ADHD medications

A
  • sleep disturbance
  • suppressed appetite
  • headache
  • suppressed growth of height
  • hallucination, psychotic symptoms
19
Q

DDx of ADHD

A
  • thyroid dysfunction
  • hypoglycemia
  • anemia
  • Vit B12 deficiency
  • Lead poisoning
  • head trauma
  • sleep disorder (OSA)
  • seizure
  • hearing deficit
  • fetal alcohol spectrum disorder
  • neurofibromatosis
  • medication effect
  • liver disease
20
Q

diagnosis of fetal alcohol syndrome (FAS)

A

All of the 3 +/- confirmed maternal alcohol exposure

(1) characteristic facial anomalies (see image below)   
Smooth philtrum
Thin, smooth vermilion border of the upper lip
Midface hypoplasia
Short palpebral fissures/ Microcephaly
Low nasal bridge/ short nose 
skin folds at the corner of eyes 
Microphthalmia
Strabismus
Ptosis

(2) growth retardation (intrauterine growth restriction and failure to have catch-up growth)
(3) CNS involvement (cognitive impairment, learning disabilities, or behavioral abnormalities)

21
Q

DDx of depression

A
  • persistent depressive disorder
  • adjustment disorder
  • grief reaction
  • bipolar
  • schizoaffective disorder
  • organic: substance abuse, DM, thyroid, pituitary, B12 deficiency, anemia, dementia, Parkinson’s, MS, CVA, hepatitis, OCP, BZD, beta-blockers)
22
Q

initial investigations to screen depression

A

CBC, TSH, B12, folate, lytes, CRE, LFT +/- drug screen

23
Q

Antidepressant discontinuation symptoms

A

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Flu-like symptoms 
Insomnia 
Nausea
Imbalance 
Sensory disturbance 
Hyperarousal
24
Q

s/e of SSRI

A
  • jitteriness, H/A, GI upset, insomnia, and sexual s/e (suppressed libido)
  • falls
  • hyponatremia
  • prolonged QT
  • GI bleeds
  • bone loss
  • serotonin syndrome
  • EPS
  • neuroleptic malignant syndrome
25
Q

1st line Rx for perimenopausal depression

A

desvenlafaxine (SNRIs)

26
Q

1st and 2nd line Rx for perinatal depression

A

1st line: CBT, IPT

2nd line: citalopram, escitalopram, sertraline

27
Q

diagnosis criteria of serotonin syndrome

A

Hunter’s Criteria: any of the following

  • spontaneous clonus
  • inducible clonus (or ocular clonus) & agitation & diaphoresis, tremor & hyperreflexia
  • tremor & hyperreflexia
  • hypertonia
  • fever & ocular or inducible clonus
28
Q

management of serotonin syndrome

A
  • discontinue the medications
  • restart with decreased dose / alternative
  • ER & cyproheptadine (antihistamine)
29
Q

symptoms of anticholinergic toxicity

A
  • Visual/auditory/sensory hallucinations
  • Tremulousness/myoclonic jerking
  • altered mental status (delirium), Memory impairment, cognitive impairment

Tachycardia

Dilated pupils
Difficulty adjusting visual focus (lens accommodation)
Dry eyes

Constipation
Impaired stomach emptying/increased esophageal reflux

Dry mouth/impaired speech articulation
Difficulty swallowing due to lack of saliva

Decreased sweating/dry skin

Urinary retention/overflow incontinence
Difficulty starting urination/impaired bladder emptying

30
Q

Rx for restless leg syndrome

A

1) non-ergot dopamine agonist
&raquo_space; pramipexole
&raquo_space; ropinirole

2) Alpha-2-delta calcium channel ligand
&raquo_space; Gabapentin
&raquo_space; pregabalin

31
Q

Non-pharmacological mgt for restless leg syndrome

A
  • Iron, magnesium supplement
  • Stretch calves
  • avoid caffeince
  • massage, heat
  • exercise