Psychiatry Flashcards
What’s the difference between bipolar 1 and 2?
Bipolar 1 will experience a full manic episode but bipolar 2 will experience a hypomanic episode
Bipolar 1 will have a major depressive
Bipolar 2 wont
What would you expect in a manic mental state exam
A: Flamboyantly dressed/ self neglect ( unkempt/dehydrated)
B: Overactive and hard to interview - may eat and drink greedily
S: High speech pressure, increased rate and amount, hard to interupt
M: Elated and angry mood and affect
Thought content: Inflated view, may have grandiose delusions
Form: Verbal associations, alliteration, clang association
P: Delusion either grandiose or persecutory/auditory
Insight absent
What is the ICD-10 Bipolar criteria
-
What are some differentials for bipolar?
Amphetamines, cocaine, schizophrenia
How do you treat bipolar?
Rapid access to support, consider MHA, education, review
Mood stabilisers:
- Lithium ( 0.4-1 mmol/L
- Anticonvulsants ( S.valporate, carbamazepine, lamotrigine )
- Anti psychotics in acute mania
What tests need to be carried out on a patient on lithium?
Renal function
TFT
What are the side effects lithium?
Leucocytosis
Insipid diabetes
Tremors
hypothyroidism
Increased urine
Mums! teratogenic
What do you see in lithium toxicity
Blurred vision
Coarse tremor
Muscle weakness
Ataxia
N and V
Hyperreflexia
Circulatory failure
oliguria
Seizures
Coma
How do you diagnose depression using ICD-10?
Major Symptoms:
Depressed mood
Anhedonia
Loss of energy
Minor:
Disturbed sleep
Lack of concentration
Low self confidence
Increased/ decreased appetite
Suicidal thoughts or actions
Slowing of movement or speech
Feelings of guilt, worthlessness or self reproach
2 major needed + 2 minor ( mild ) 3-4 ( moderate ) greater than 5 ( severe)
How do you treat mild/moderate depression?
- Low intensity psychological interventions
-Individual CBT
- Structured group activity - High intensity psychological intervention and/or CBT
- CBT with a proffesional
-Interpersonal therapy
- Couples therapy - Consider different AD therapy or escalate
Skip to AD is its been over 2 years
Why are SSRI’s first line instead of TCA?
TCA are dangerous in an overdose ( lofepramine has best safety profile)
Why are SSRI’s first line instead of TCA?
TCA are dangerous in an overdose ( lofepramine has best safety profile)
What the different types of therapy?
CBT: A type of talking behaviours’ that changes the processes underpinning the thoughts and behaviours related to a patients on symptoms, 1-1 with a mental health individual or in a group
Interpersonal: Adresses communication between people
Behavioural Activation: Identifies depression loops to make small changes in lifestyle ( LINK BETWEEN ACTIVITES AND MOOD)
Mindfulness and meditation
Counselling: Focus on emotional processing and helps people find there own solutions
STPP: Difficult feelings in significant relationships and patterns
Individual problem solving: Goal orientated and structures, resolving current issues
Couples therapy: Relationship problems
What puts you at an increased risk for a depressive episode relapse?
History of recurrent episodes over the last 2 years
Incomplete response to treatment
Avoidance and rumination unhelpful coping styles
History of severe depression
Depression has functional impairment
Chronic Physical health
Mental health problems
Chronic physical health and mental health problems
Personal/social and environmental factors that are ongoing
What happens if a person has not responded after 4 weeks of AD’s?
Ask about:
- Any external factors, physical or mental health conditions
- adherence and side effects
-Review diagnosis and think about comorbid conditions
- Increasing dose and think about switching to a different class
What are some names and side effects of SSRI’s?
Sertraline, citalopram and fluoxetine
Nausea, indigestion, worsening sexual function, increases suicidal ideation, serotonin syndrome
What are some names and side effects of SNRI?
Venlafaxine and Duloxetine
V - Raised BP and is CI in heart disease
same as SSRI
What are some names and SE of TCA?
Amitryiptyline and Dosulepin
Dry mouth, tachycardia, constipation, sleepiness, weight gain and worse in an overdose
What are some names and SE of MAO-I?
Phenelzine and moclobemide
Can cause high BP if taken with tyramine found in cheese, meats and broad beans
What is an atypical antidepressant?
Mirtazipine - drowsy and weight gain
What are some risk factors for suicide?
Alcohol or substance misuse
Bipolar
Personality disorder
Previous attempts
Physical or sexual abuse
Possession of firearms
Incarceration
Chronic Pain
Isolation
Age
Depression
Violent methods
Physical health problems
High risk employment
Bereavement
Relationship changes
What are some warning sines of suicide?
Obsessive thoughts surrounding death
Feelings of hopelessness, worthlessness and helplessness
Final acts - financial affairs, saying goodbye, writing wills
What are some examples of protective factors?
Supportive relationships
Children
Pets
Religion
Coping
How do you manage self harm risk?
No immediate risk - refer to crisis and home treatment
Mental health disorder of severity requiring management - community mental health or CAMHS
High Risk: if they decline - MHA and admit inpatient
What are some risk factors for EUPD?
Family history of BPD, bipolar or addiction
Brain development - amygdala, hippocampus, orbitofrontal cortex
Emotional, physical or sexual abuse
Exposed to fear or distress as a child
neglect
What are some symptoms of BPD?
Emotional Instability - Affective dysregulation
Disturbed patterns of thinking or perception - cognitive distortions or perceptual distortions
Impulsive behaviour
Intense and unstable relationships with others
Severe mood swings over short time periods e.g. suicidal then positive
low self esteem and intense feel of rejection , abandonment and unloved
Can develop intense feelings for people but lose them, hard to control emotions
Engage in risky behaviours - self harm, overdose, sexual activities
Hard to cope with life
What is the criteria for a delusion
Held with certainty - cannot be rationalized
Incorrigibility - not changeable
Impossibility of content
Doesn’t make sense in context of social cultural and religious upbringing
What is the difference between a primary and secondary delusion?
Secondary can be understood in the light of an abnormal mental state - delusions of poverty in a depressed patient
Primary cannot be understood this way and must have come from a pathological process
What are the first rank symptoms of schizophrenia?
- Auditory Hallucinations
- Voices heard arguing
- Thought echo
-Running commentary - Delusions of thought interference
- Thought insertion
- thought withdrawal
- thought broadcasting - Delusions of control
- Passivity of affect
- Passivity of impulse
- Passivity of volitions
- Somatic passivity - Delusional Perception
- primary delusion that is reported after the experience of normal perception
-
What is psychomotor retardation
Everything slows down, little movement and tasks are done very very slowly
What is Catatonia
Seen in schizophrenia
Periods of motor excitation and then non responding like being in a coma but will respond to pain
What is waxy flexibility?
Bend an arm into a position and it stays there like wax
Encephalitic type problems
What are some abnormal movements
Tremors , tics
What is Akathisia
Restlessness - side effect of antipsychotics
What is tardive dyskinesia
Late onsent
Unusual chewing movements
Neurological side effect of antipsychotics
Grimacing
Patient unaware
What is Poverty of thought
Not many thoughts - speech is very slow
What is flight of ideas
One thought after another
Often presents with pressured speech
What is clang associations
One association after another
What is rhyming
Rhyming words
What is Perseveration
Same answer to every question - cognitive impairment like dementia
What is loosing of association
Tangential thinking
Loose association but doesnt answer the question
What is circumstantial
Go round and round but come at an answer