Psychiatry Flashcards
What are mood disorders?
Group of illnesses that cause serious changes in the emotional status & interfere with day to day activities
What are risk factors for mood disorders?
Family hx & Personal Trauma
What neurotransmitters affect mood?
Serotonin (Obsessions, Compulsions), Norepinephrine (Anxiety, Attention), and Dopamine (Attention, Motivation, and Pleasure)
What are the Depressive Disorders?
Major Depressive Disorder, Substance/Medication-induced depressive disorder, Depressive disorder due to another medical condition, adjustment disorder with depressed mood, premenstrual dysphoric disorder
What are the 9 Major Symptoms of Depressive Episodes?
- Depressed, Hopeless, lacks sense of purpose
- diminished interest in an activity once pleasurable (anhedonia)
- Weight gain or loss, change in appetite
- sleeping habit changes
- changes in energy level
- the persistent feeling of worthlessness
- excessive guilt
- difficulty concentrating
- Suicidal ideation
What are Major Depressive Disorder Criteria?
- Episodes lasting at least 2 weeks
- Changes in affect, Cognition, Neurovegative function
- Must include 5 of the major symptoms; 2 should be:
Persistence of depressive mood & anhedonia
What are the subtypes of MDD?
Depression w/ atypical features
Postpartum Depression
Major Depressive Disorder w/ seasonal pattern
Major Depressive Disorder w/ Psychotic Features
What is Depression w/ Atypical Features?
- Mood Reactivity (Improved mood when exposed to pleasureable or positive events)
- Rejection Sensitivity (feeling anxious & overreact at the slightest evidence of rejection)
Other Features: Hyperphagia, Hypersomnia, Leaden Paralysis
What is postpartum Depression?
Onset occurs before childbirth usually
Depression either during or 4-6 weeks after delivery
What is MDD w/ Seasonal Pattern?
- at least 2 depressive episodes during cold months for the past 2 years
- no hx of depressive episodes appearing in non-seasonal pattern
What is Persistent Depressive Disorder?
Mild symptoms
2 or more:
- change in appetite
- change in sleep
- fatigue
- decreased self-esteem
- decreased concentration
- difficulty making decisions
- hopelessness or pessimism
What are Manic Episodes?
- last at least 1 week
- at least 3 of the 7 symptoms present:
1. Inflated self-esteem or grandiosity
2. More talkative than usual
3. Urgency to keep talking
4. Racing Thoughts
5. Easily Distracted or excessive attention to irrelevant things
6. Need to achieve certain things
7. Reckless
What is the difference between Manic and Hypomanic?
A milder version of at least 3 of the same symptoms as manic episodes
- lasts at least 4 days
How do you treat Mild Depression & Bipolar Disorders?
No medication needed
- Psychotherapy (CBT)
- Talk Therapy
- Interpersonal Therapy
- Physical Activity (~20 mins 3x/week)
- Eating a high-fiber diet
- Bright light therapy (seasonal pattern MDD)
What are the pharmacological options for MDD?
Selective Seratonin Reuptake Inhibitors (SSRIs)
- Fluoxetine, Paroxetine, Sertraline
Serotonin & Norepinephrine Reuptake Inhibitors
- Venlafaxine, Desvenlafaxine, Duloxetine
Atypical Antidepressants
- Bupropion, Mirtazapine
Tricyclic Antidepressants
- Doxepin, Amitriptyline
Monoamine Oxidase Inhibitors (MAOIs)