Psychiatric Meds Flashcards
haloperidol (class, SE)
haldol
class: 1st generation antipsychotic, high potency
SE: EPS
fluphenazine (class, SE)
prolixin
class: 1st generation antipsychotic, high potency
SE: EPS
chlorpromazine (class, SE)
thorazine
class: 1st generation antipsychotic, low potency
SE: HAM (orthostasis, sedating–avoid in elderly)
quetiapine (class, SE)
seroquel
class: 2nd generation antipsychotic
SE: metabolic syndrome, extremely sedating, causes orthostasis
olanzapine (class, SE)
zyprexa
class: 2nd generation antipsychotic
SE: metabolic syndrome (worst), sedating
ziprasidone (class, SE)
geodon
class: 2nd generation antipsychotic
SE: metabolic syndrome (least), QT prolongation
risperidone (class, SE)
risperdal
class: 2nd generation antipsychotic
SE: most “typical” = EPS, metabolic syndrome
aripiprazole (class, SE)
abilify
class: 2nd generation antipsychotic
SE: metabolic syndrome (least)
novel MOA = partial DA agonist
clozapine (class, SE)
clozaril
class: 2nd generation antipsychotic
SE: metabolic syndrome, agranulocytosis (follow WBC), sezirues, cardiomyopathy, hypotension, drooling
good for TD, decrease suicide, most effective but most dangerous
1st generation antipsychotic SE
high potency more EPS
low potency more HAM
2nd generation antipsychotic SE
metabolic syndrome
1st generation antipsychotic MOA
D2 antagonism
2nd generation antipsychotic MOA (+ exception)
D2 and 5HT2A antagonism
EPS
acute dystonia, akathisia, parkinsonism, TD, NMS
anti-histamine
weight gain, sedation
anti-alpha1
orthostasis, cardiac arrhythmias
anti-muscarinic (Ach)
delirium, blurred vision, xerostomia, constipation, urinary retention
SE of all antipsychotics
all lower seizure threshold, only clozapine known to induce seizures, all potentially prolong QTc
