Psychiatric Meds Flashcards
haloperidol (class, SE)
haldol
class: 1st generation antipsychotic, high potency
SE: EPS
fluphenazine (class, SE)
prolixin
class: 1st generation antipsychotic, high potency
SE: EPS
chlorpromazine (class, SE)
thorazine
class: 1st generation antipsychotic, low potency
SE: HAM (orthostasis, sedating–avoid in elderly)
quetiapine (class, SE)
seroquel
class: 2nd generation antipsychotic
SE: metabolic syndrome, extremely sedating, causes orthostasis
olanzapine (class, SE)
zyprexa
class: 2nd generation antipsychotic
SE: metabolic syndrome (worst), sedating
ziprasidone (class, SE)
geodon
class: 2nd generation antipsychotic
SE: metabolic syndrome (least), QT prolongation
risperidone (class, SE)
risperdal
class: 2nd generation antipsychotic
SE: most “typical” = EPS, metabolic syndrome
aripiprazole (class, SE)
abilify
class: 2nd generation antipsychotic
SE: metabolic syndrome (least)
novel MOA = partial DA agonist
clozapine (class, SE)
clozaril
class: 2nd generation antipsychotic
SE: metabolic syndrome, agranulocytosis (follow WBC), sezirues, cardiomyopathy, hypotension, drooling
good for TD, decrease suicide, most effective but most dangerous
1st generation antipsychotic SE
high potency more EPS
low potency more HAM
2nd generation antipsychotic SE
metabolic syndrome
1st generation antipsychotic MOA
D2 antagonism
2nd generation antipsychotic MOA (+ exception)
D2 and 5HT2A antagonism
EPS
acute dystonia, akathisia, parkinsonism, TD, NMS
anti-histamine
weight gain, sedation
anti-alpha1
orthostasis, cardiac arrhythmias
anti-muscarinic (Ach)
delirium, blurred vision, xerostomia, constipation, urinary retention
SE of all antipsychotics
all lower seizure threshold, only clozapine known to induce seizures, all potentially prolong QTc
lithium (class, SE)
class: mood stabilizer
decreases suicide
SE: neurotoxicity, hypothyroid, DI, leukocytosis, GI
Teratogenicity: Ebsteins Anomaly
carbamazepine (class, SE)
class: mood stabilizer
SE: autoinducer at liver (decreases self and VPA), S/J rash, CBC abnl
Teratogenicity: craniofacial defects
valproic acid (class, SE)
class: mood stabilizer
SE: hepatitis, CBC abnl, sedation, weight gain
Teratogenicity: neural tube defect
2 drugs that decrease suicide risk
Li and clozapine
lamotrigine
lamictal
class: mood stabilizer, antiepileptic
great for prevention of depression
SE: S/J rash
phenilzine
nardil
class: antidepressant, MAOI
tranylcypromise
parnate
class: antidepressant, MAOI
selegiline
emsam
class: antidepressant, MAOI
amitriptyline
class: antidepressant, TCA
pain syndromes
clomipramine
class: antidepressant, TCA
OCD
imipramine
class: antidepressant, TCA
enuresis
nortriptyline
class: antidepressant, TCA
elderly
MAOI MOA, SE
MOA: MAOA–5HT and NE; MAOB–DA
SE: NE–> malignant HTN (avoid tyramine-rich food (aged/cured))
5HT–> serotonin syndrome
can overdose
TCA MOA, SE
MOA: increase 5HT, NE
SE: anti-HAM, torsade
can overdose
SNRI MOA, SE
MOA: increase 5HT, NE
SE: 5HT and NE (diastolic HTN)
venlafaxine
class: antidepressant, SNRI
duloxetine
class: antidepressant, SNRI
SSRI MOA, SE
MOA: 5HT
SE: 5HT
paroxetine
class: antidepressant, SSRI
citalopram
class: antidepressant, SSRI
escitalopram
class: antidepressant, SSRI
fluoxetine
class: antidepressant, SSRI
fluvoxamine
class: antidepressant, SSRI
sertaline
class: antidepressant, SSRI
buproprion
class: antidepressant, NDRI
mirtazapine
class: antidepressant, alpha2 antagonist
trazodone
class: antidepressant, SARI
nefazodone
class: antidepressant, SARI
