psychiatric drugs Flashcards
important drug categories (5)
*antidepressants
*antipsychotics
*anxiolytics
*mood stabilizers
*stimulants
major antidepressant classes (4)
*MAOIs (Monoamine oxidase inhibitors)
*TCAs (Tricyclic antidepressants)
*SSRIs (Selective serotonin reuptake inhibitors)
*SNRIs (serotonin norepinephrine inhibitors)
common side effects of antidepressants (4)
*weight changes
*sexual dysfunction
*mood changes
*anticholinergic effects
MAOI unique characterisitics
avoid foods with tyramine
tricyclic unique characteristics
risk of orthostatic hypotension
SSRI/SNRI unique characteristic
risk of serotonin syndrome
triggers serotonin syndrome
increase in serotonin
causes increased serotonin leading to serotonin syndrome
*sudden changes in antidepressant dose
*taking multiple antidepressants
*taking antidepressant with st. john’s wort
S/S of serotonin syndrome (3)
*restlessness
*increased VS (esp HR and BP)
*muscle rigidity
how alcohol detox affects glutamate
increases levels
how long for antidepressants to have effect
4-6 weeks
focus of 1st gen antipsychotics
positive symptoms (hallucinations, delusions, other added to reality symptoms)
focus of 2nd gen antipsychotics
negative symptoms (not wanting to do things like get out of bed or shower)
common antipsychotic symptoms (2)
*sedating
*risk of poor compliance
unique characterisics of clozapine
*requires routine blood draws
*agranulocytosis (decrease in white blood cells, depressing immune response)
unique characteristic of long-acting injectables (how often needed)
1 injection lasts 1-3 months; less side effects
used as mood stabilizers
*mood stabilizers
*anticonvulsants
*others
mood stabilizer characterisitics
*weight gain
*have therapeutic range (watch for toxicity)
*risk for noncompliance
*takes time to reach therapeutic levels
lithium range
0.-1.2
lithium toxicity causes
kidney damage
classes of anti-anxiolytic meds (2)
*benzodiazepines
*non-benzodiazepines
benzodiazepines
*controlled
*very addictive
*sedating
*appears in urine tox screen
*stopping abruptly=detox (dangerous)
non-benzodiazepines
*antihistamines (benadryl, hydroxyzine)
*BP meds (propanolol)
*buspar
*antipsychotics (seroquel, haldol)
detox alcohol with
benzodiazepines