Psychiatric aspects of HIV Flashcards

1
Q

Timing of symptoms of HIV-associated acute stress reaction

A

Appear minutes to hours after the patient is informed of their diagnosis
Remit within 2-3 days

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2
Q

Most common psychiatric condition among patients with HIV

A

Depression

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3
Q

Prevalence of depression among patients with HIV

A

40%

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4
Q

First line antidepressants for patients with depression and HIV

A

SSRIs

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5
Q

Antipsychotic least likely to cause EPSEs among patients with HIV

A

Risperidone

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6
Q

Most common reason for psychiatric admission among patients with HIV

A

Mania

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7
Q

Predictive markers for HIV dementia

A

B2-microglobulin and neopterin levels in CSF
CD41 cell counts

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8
Q

Clinical feature of HIV dementia that fits with a ‘subcortical dementia’

A

Naming and vocabulary skills are usually preserved even in advanced cases

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9
Q

Disease suggested by CT/MRI findings of multiple bilateral ring enhancing lesions in a patient with HIV

A

Cerebral toxoplasmosis

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10
Q

Disease suggested by CT/MRI findings of contrast-enhancing mass lesions in a patient with HIV

A

CNS lymphoma

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11
Q

HIV treatment which may prevent associated cognitive impairment

A

zidovudine

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12
Q

Psychostimulant found to improve cognitive function in patients with HIV dementia

A

Methylphenidate

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13
Q

Papovirus infection associated with HIV which causes rapid dementia and death

A

Progressive multifocal leucoencephalopathy

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14
Q

Parasite associated with cerebral toxoplasmosis

A

Toxoplasma gondii

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15
Q

Treatment for cerebral toxoplasmosis

A

Pyrimethamine
Sulphadiazine

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16
Q

Features of cryptococcal meningitis

A

Headache
Meningism
Photophobia
Nausea
Fever
Delirium

17
Q

Treatment for cryptococcal meningitis

A

IV amphotericin B

18
Q

Virus associated with primary CNS lymphoma

A

EBV

19
Q

Features of primary CNS lymphoma

A

Seizures
Personality changes
Headache
Focal deficits
No fever

20
Q

Psychiatric side effects of zidovudine

A

Confusion
Agitation
Insomnia
Mania
Depression

21
Q

Psychiatric side effects of stavudine

A

Peripheral neuropathy

22
Q

Psychiatric side effects of didanosine

A

Peripheral neuropathy
Mania

23
Q

Psychiatric side effects of zalcitabine

A

Peripheral neuropathy

24
Q

Psychiatric side effects of efavirenz

A

Depression
Psychosis

25
Q

HIV treatment most associated with psychiatric side effects

A

Efavirenz

26
Q

Psychotherapy treatment with evidence for HIV associated depression

A

Interpersonal therapy

27
Q

Duration of symptoms required for a diagnosis of HIV dementia

A

1 month

28
Q

Most common pathogen in the CNS in patients with HIV

A

Cerebral toxoplasmosis

29
Q

CT/MRI appearances of cerebral toxoplasmosis

A

Multiple enhancing ring lesions

30
Q

HIV related illness where Indian ink staining can be used for diagnosis

A

Cryptococcal meningitis

31
Q

Most common cause of retinitis in HIV

A

CMV

32
Q

Fundoscopy appearances in patients with CMV

A

Mozarella pizza appearances

33
Q

Most common extra pulmonary TB infection in patients with HIV

A

Cerebral TB

34
Q

Pathology behind progressive multifocal encephalopathy in patients with HIV

A

Papovirus infection affecting the white matter

35
Q

HIV treatment associated with mania and suicide

A

Efavirenz