Psychiatric aspects of HIV

Question 1

Timing of symptoms of HIV-associated acute stress reaction

Answer 1

Appear minutes to hours after the patient is informed of their diagnosis
Remit within 2-3 days

Question 2

Most common psychiatric condition among patients with HIV

Answer 2

Depression

Question 3

Prevalence of depression among patients with HIV

Answer 3

40%

Question 4

First line antidepressants for patients with depression and HIV

Answer 4

SSRIs

Question 5

Antipsychotic least likely to cause EPSEs among patients with HIV

Answer 5

Risperidone

Question 6

Most common reason for psychiatric admission among patients with HIV

Answer 6

Mania

Question 7

Predictive markers for HIV dementia

Answer 7

B2-microglobulin and neopterin levels in CSF
CD41 cell counts

Question 8

Clinical feature of HIV dementia that fits with a ‘subcortical dementia’

Answer 8

Naming and vocabulary skills are usually preserved even in advanced cases

Question 9

Disease suggested by CT/MRI findings of multiple bilateral ring enhancing lesions in a patient with HIV

Answer 9

Cerebral toxoplasmosis

Question 10

Disease suggested by CT/MRI findings of contrast-enhancing mass lesions in a patient with HIV

Answer 10

CNS lymphoma

Question 11

HIV treatment which may prevent associated cognitive impairment

Answer 11

zidovudine

Question 12

Psychostimulant found to improve cognitive function in patients with HIV dementia

Answer 12

Methylphenidate

Question 13

Papovirus infection associated with HIV which causes rapid dementia and death

Answer 13

Progressive multifocal leucoencephalopathy

Question 14

Parasite associated with cerebral toxoplasmosis

Answer 14

Toxoplasma gondii

Question 15

Treatment for cerebral toxoplasmosis

Answer 15

Pyrimethamine
Sulphadiazine

Question 16

Features of cryptococcal meningitis

Answer 16

Headache
Meningism
Photophobia
Nausea
Fever
Delirium

Question 17

Treatment for cryptococcal meningitis

Answer 17

IV amphotericin B

Question 18

Virus associated with primary CNS lymphoma

Answer 18

EBV

Question 19

Features of primary CNS lymphoma

Answer 19

Seizures
Personality changes
Headache
Focal deficits
No fever

Question 20

Psychiatric side effects of zidovudine

Answer 20

Confusion
Agitation
Insomnia
Mania
Depression

Question 21

Psychiatric side effects of stavudine

Answer 21

Peripheral neuropathy

Question 22

Psychiatric side effects of didanosine

Answer 22

Peripheral neuropathy
Mania

Question 23

Psychiatric side effects of zalcitabine

Answer 23

Peripheral neuropathy

Question 24

Psychiatric side effects of efavirenz

Answer 24

Depression
Psychosis

Question 25

HIV treatment most associated with psychiatric side effects

Answer 25

Efavirenz

Question 26

Psychotherapy treatment with evidence for HIV associated depression

Answer 26

Interpersonal therapy

Question 27

Duration of symptoms required for a diagnosis of HIV dementia

Answer 27

1 month

Question 28

Most common pathogen in the CNS in patients with HIV

Answer 28

Cerebral toxoplasmosis

Question 29

CT/MRI appearances of cerebral toxoplasmosis

Answer 29

Multiple enhancing ring lesions

Question 30

HIV related illness where Indian ink staining can be used for diagnosis

Answer 30

Cryptococcal meningitis

Question 31

Most common cause of retinitis in HIV

Answer 31

CMV

Question 32

Fundoscopy appearances in patients with CMV

Answer 32

Mozarella pizza appearances

Question 33

Most common extra pulmonary TB infection in patients with HIV

Answer 33

Cerebral TB

Question 34

Pathology behind progressive multifocal encephalopathy in patients with HIV

Answer 34

Papovirus infection affecting the white matter

Question 35

HIV treatment associated with mania and suicide

Answer 35

Efavirenz