Psychedelics Flashcards
- There is an inherent bias towards minorities, which results in lower:
PRESCRIPTIONS.
- According to Dr. Harding, minorities experience excessive wait times for appointments.
TRUE.
- The national average for uninsured Hispanic individuals is:
30%
- In order to improve services for minorities, Dr. Harding recommends that providers:
Advocate for diversity representation in clinical trials, provide a similar level of care to all groups, identify, create or improve diversity goals so that your practice represents the demographic distribution of your area.
- To improve timeliness with regard to excessive wait times for appointments for minorities recommends:
Being compassionate and flexible, within reason, for missed and late appointments and work with a local non-emergency medical transportation group to accommodate travel for qualified patients.
- To improve the psychedelic psychotherapy workforce, Dr. Harding recommends:
Supporting and promoting diversity on staff, boards, and other leadership positions, providing translation services, or hiring bilingual staff to support languages spoken locally and connecting with diverse providers in your area to collaborate on patient care.
- The first PTSD trial for MDMA-assisted therapy began in:
2003.
- Studies show that MDMA promotes fear extinction in mice and modifies fear memories during reconsolidation in rats.
True.
- Which of the following do Dr. Yazar-Klosinski and Amy Emerson recommend for MDMA-assisted therapy set and setting?
Music to support experience, periods of going inward, elements of mindfulness and empathetic rapport and presence.
- According to Dr. Yazar-Kolinski and Amy Emerson, about _______ adults have PTSD during a given year.
8 million.
- Which of the following secondary benefits were found in the Phase 2 studies of MDMA-assisted therapy?
Durable reduction in alcohol use.
- Which of the following factors may help lead to expanded access to MDMA-assisted therapy, and accelerating access to treatment.
Test risk mitigation procedures in a clinical treatment setting, collect safety-related health outcome data and establish centers of excellence.
- Race is an organizing concept that is interwoven into the structure of the United States in particular, according to Resmaa Menakem.
True.
- Resmaa Menakem requires that organizations that want to work with him by doing one year of container building have at least _____ of their organization participate.
10%.
- Resmaa Menakem’s definition of _______ is that the white body deems and has deemed itself the supreme standard by which all bodies’ humanity shall be measured, structurally and philosophically.
White body supremacy.
- Every victim has a ________ underbelly, according to Resmaa Menakem.
Perpetrator.
_________ developed the concept of intersectionality.
- Kimberle Crenshaw
- According to Resmaa Menakem, we will see a racialization component show up in terms of ________ psychedelics.
W ho is allowed to use, who is allowed to administer and who is allowed to work with
- According to Dr. Oxley & Dr. Prashad, after a patient fails to respond to two antidepressants, the chance of responding to a third medication drops to:
16%.
- Which of the following conditions may be treatable with ketamine?
Suicidal thoughts, bipolar depression, obsessive compulsive disorder and post traumatic stress disorder.
- According to Dr. Prashad and Dr. Oxley, ________ of patients typically respond to ketamine treatment.
70-80%.
- A burst of _______ seems to initiate the pathways that are believed to be involved in strengthening and formation of new neuronal connections, which is how ketamine works to treat certain conditions.
Glutamate.
- Side effects of nasal esketamine may include:
Dissociation, nausea/vomiting, sedation and increased blood pressure during treatment.
- Ketamine can be used concurrently with most standard antidepressants without reducing efficacy or increasing side effects. True
True.
- According to Dr. Schwartz, which of the following may be indicative of acute trauma stress
Feelings of irritability and anger, somatic symptoms of shakiness and nausea and feelings of fear and sadness.
- The _______ is the hub for sensory and motor nerves, including the vagus nerve.
Medulla.
- According to Dr. Schwartz, the ________ is involved in learning and is responsible for storage and retrieval of long term, explicit memories for facts.
Hippocampus.
- The social nervous system is:
Influenced by the attachment relationship (vagal tone of the mother), is strengthened by repeated practice, which myelinates the nerve pathways and functions as a fine-tuned brake.
- According to Dr. Schwartz, the “fight” stage of the trauma response involves SNS (social nervous system):
False.
- The integration of the upper and lower brain centers facilitates:
Regulation, reflection, self-control and impulse control.
- In order to effectively co-regulate, Dr. McCowan recommends that therapists work on their presence prior to session through:
Mindfulness, grounding, body scan, breathing.
- A therapist is considered to be present if they are:
Immersed in the moment.
- Which of the following may be barriers to presence?
Not being present in our relationships and lives outside the session, lacking mindfulness or intention in our routines and preparation before the session, lacking the necessary and intentional self-care and distraction and disconnection during the session.
- Cultural background and identity can influence both the therapist’s and participant’s biases, verbal/nonverbal expression, and conceptualization of symptoms or conditions.
True.
- According to Dr. McCowan, therapist self-care may help:
Reduce vicarious trauma.
- Which of the following questions does Dr. McCowan recommended asking for self-care and cultivating presence?
How do I work with tension or stress in my body? How much time do I spend in nature? Am I nourished or drained in my relationships? What brings me joy and pleasure, and am I making space for this?
- According to Dr. mate, in the shamanic tradition, shamans do not go through formal learning, they instead go through their own deep healing process before coming shamans.
True.
- In any form of therapy, what fundamentally makes the difference in effective healing work is:
How the therapist shows up for their client.
- According to Dr. Mate, it is appropriate for therapists to share details about themselves with their patients if ____________ is the intention.
Communicating their understanding of a shared experience.
- ___________ is not a state, but an ongoing process, according to Dr. Mate.
- Self-regulation.
- According to Dr. Mate, the most important aspect of the healing process is the:
Quality of the therapeutic alliance.
- Individuals with a strong, tenacious intellect may use that as a defense against:
Self-awareness and vulnerability.
- According to Dr. Richards, which of the following alternate terms may be used in place of “psychedelic” :
Hallucinogenic, psycholytic, entheogenic, phantastical.
- Which of the following is indicative of mystical consciousness, according to Dr. Richards:
Transcendence of time and space, deeply-felt positive mood, intuitive knowledge and unity.
- According to Dr. Richards, ineffability may involve:
The need for words that do not exist yet
- Potential applications of psychedelics in medicine may include the treatment of addictions according to Dr. Richards.
True.
- If the data supports it, Dr. Richards recommends facilitating the reclassification of __________ off of schedule 1/ClassA.
Psilocybin.
- Who said, “The essence of the spiritual life is feeling gratitude”?
David Steindl-Rast.
- Who synthesized and discovered ketamine?
Calvin Stevens.
- According to Dr. Wallach, a key difference between dissociative drugs and classical hallucinogens is the _________ effect.
Disembodiment.
- Which of the following are considered to be indirect effects of ketamine?
Increased glutamate signaling, increased monoamine signaling and hormone and neurotrophic factor release: BDNF, cortisol, beta-endorphin.
- The NMDA receptor is a glutamate ion channel found in the central nervous system and periphery, and plays an important role in?
Synaptic signaling, plasticity, learning and memory and cell survival.
- Research indicates that Rapamycin ________ the antidepressant response rate of ketamine at two weeks following treatment.
Triples.
- Which of the following is a main competency category of the IPI Psychedelic Assisted Psychotherapy Training Program?
Research and science, therapeutic process, professional development, and intrapersonal development.
- The research and science competency category will include reviewing ___________ in the IPI Psychedelic Assisted Psychotherapy Training Program.
Dosing protocols.
- Discussion of mechanism of action will be included as part of the research and science competency category in the IPI Psychedelic Assisted Therapy Program?
True.
- The IPI program will cover __________.
Mystical experiences.
- Professional development topics will include __________ at IPI.
Harm reduction, cultural competency, policy and advocacy and professional liability.
- Transference and countertransference will be covered as part of the _______ competency category at IPI.
Intrapersonal Development.
- According to Rick Doblin, ________ revitalized the psychedelic therapy underground in the 1970’s-80’s.
MDMA.
- MAPS (Multidisciplinary Association for Psychedelic Studies) was founded in ______.
1986.
- According to Rick Doblin, the FDA requires _________ for studies on neuroscience and psychedelics.
Proof of Safety and Proof of Efficacy.
- Psychedelics for substance abuse have a large role to play, both to help people work through traumas and breakthrough to sense of connection and connection.
True.
- According to Dr. Doblin, which of the following indications may psychedelics be used as a treatment modality?
Anxiety, depression and end of life anxiety.
- For the way materials emerge from patients under psychedelics, a traditional approach to psychotherapy is too
Directive, focused and structured.
- According to Dr. Raison, psilocybin produces profound effects on consciousness primarily through ________ agonism.
5-HT2A.
- Low entropy states are more _______ according to Dr. Raison.
Rigid.
- Which of the following are considered to be high entropy states according to Dr. Raison?
Psychedelic state, dreaming/REM sleep and early psychosis.
- According to Dr. Raison, reductions in experiential avoidance are associated with symptom improvement.
True.
- A series of small academic studies suggest psilocybin holds promise for the treatment of:
Cancer-related distress, major depression, treatment-resistant depression and substance use orders.
- Psilocybin produces acute CNS (central nervous system) effects that support profound emotional/cognitive experiences that are associated with long-term therapeutic effects.
True.
- According to Shannon Carlin, a practitioner’s commitment and devotion involves supporting another person in their:
Awe of existence and one’s place in it, restoring of trust and faith in humanity and one’s self, relating and reconnecting with their own wisdom and experience and process of meaning making and discovery of purpose.
- Which of the following are considered to be principles of psychedelic ethics according to Shannon Carlin?
Safety, transparency, confidentiality and privacy, sexual boundaries.
- Shannon Calin recommends that at the time of intake and before each medicine session, practitioners ask their client to commit to safety agreements that include not driving a vehicle after the session, informing staff of thoughts of harming self or others, and staying on-site until medical staff say it is safe to go home.
True.
- According to Shannon Carlin, if a person lacks capacity to consent during a session the practitioner should:
Continue treatment according to their previous informed consent.
- Shannon Carlin recommends that representatives of the psychedelic therapy:
Accurately say there is a lot we do not know.
- Ethical decision making involves:
A commitment to do the right thing, awareness to apply morals and act consistently and competency to assess information, identify alternatives, consequences and risks.
- In 1955 _________ started to use LSD in psychotherapy.
Leuner & Sandison.
- In the 1960’s, ________ publications were made on psychedelics.
8,000.
- The European Society for Psycholytic Therapy was established in:
1964.
- The term psycholysis was coined by Sandison in 1960.
True.
- Which of the following diagnoses did studies show may be treated with psychedelic psychotherapy:
Anxiety neuroses, depressive neuroses, OCD.
- The stagnated-Fragmented course in psycholytic therapy may induce:
Erratic flow of experience.
- According to Michael Pollan, when the goal is to test the efficacy and safety of psychedelics in treating mental illness, the FDA (food and drug administration) and DEA (Drug enforcement administration) have been:
Supportive.
- Decriminalizing personal possession and growing psychedelics is the correct path to follow, according to Michael Pollan .
True.
- Michael Pollan’s concerns around commercializing psychedelics include:
Capitalism cheapening them, psychedelics being pushed onto people and commodifying something sacred.
- The Native American community has developed a very safe and effective healing method through the use of peyote by:
Ritualizing the experience, not commercializing the medicine, always involving an elder and typically ingesting the medicine in a group.
- Michael Pollan sees particular value in the use of psychedelics in the ______ population due to the medicine’s ability to shift ingrained patterns of thinking and behavior.
Older.
- Wild peyote takes _______ to grow.
15 years.
- According to Dr. Wickramesekera, which of the following alters both the DMN (default mode network) and the experience of self?
LSD, ayahuasca, MDMA, psilocybin.
- ___________ is considered to be a common phenomenon in altered states of consciousness, according to Dr. Wickramasekera.
Time distortion.
- According to Dr. Wickramasekera, a PCI (perturbational complexity index) given after an altered state of consciousness quantitatively assesses:
Experience of time distortion, involuntariness and flow and experience of unitive consciousness.
- Suggestibility in altered states of consciousness does not correlate with suggestibility outside of altered states of consciousness according to Dr. Wickramasekera.
True.
- According to Dr. Wickramasekera, ___________ can effect the type of relationship a patient experiences in psychedelic psychotherapy, particularly if they experience transference.
Insecure Attachment.
- The diathesis stress model suggests that people with an insecure attachment style may be more susceptible to _________ in psychedelic therapy.
Suggestion and dissociation.
- Transference is a normal and expected part of the therapeutic process.
True.
- Which of the following is an example of negative countertransference?
Feeling overwhelmed or anxious in session.
- Responding to transference does not include which of the following steps?
Gossiping with coworkers about your feelings toward the client.
- Which of the following responses is beneficial when responding to a client’s fear of losing control?
Making supportive statements of safety and connection.
- Providing empathetic presence in the face of intense distress is an essential element of psychedelic assisted therapy.
True.
- Who is responsible for assuring that erotic transference and counter transference is never acted upon?
The practitioner.
- Transpersonal psychology is considered to be _______ part of the in western psychology.
Fourth force.
103.________ proposes that at the core of the world’s religions lies a universal, fundamental, mystical truth regarding the nature of the self, consciousness and ultimate reality.
Perennial philosophy.
- Which of the following is a central characteristic of the mystical state?
Ineffability, noetic quality, transiency and passivity.
- _________ possesses a chemical structure similar to the neurotransmitter serotonin.
Psilocybin.
- ___________ is an intuitive response of awe, humility, holiness, reverence and wonder in the presence of inspiring reality.
Sacredness.
- _________ of Americans say they have had a religious or mystical experience.
49%.
- According to Dr. Prashad, which of the following conditions may be treated with Ketamine?
Suicidal thoughts, bipolar depression, obsessive compulsive disorder and PTSD.
- Up to _______ of patients will fail to respond to multiple attempts at treatment through ketamine.
1/3.
- Which of the following would constitute an exclusion from receiving ketamine treatments?
Pregnancy, uncontrolled hypertension, active mania, glaucoma.
- According to Dr. Prashad the doses of ketamine used for psychiatric indications are higher than those used in abuse populations.
False.
- Many providers report that ________ decreases the efficacy of ketamine.
Lamotrigine.
- According to Dr. Prashad, ketamine has been found to increase physiological response during opioid withdrawal.
False.
- If an individual is actively using ________, ketamine treatments can be dangerous due to increased blood pressure.
Marijuana, opioids, cocaine and alcohol
- Which of the following are considered to be characteristics of borderline personality disorder? Anger outbursts, extreme emotional swings, unstable relationships and fear of abandonment.
Anger outbursts, extreme emotional swings, unstable relationships and fear of abandonment.
- Multiple studies indicate that ketamine is associated with exacerbation of core psychotic and cognitive symptoms in ________.
Schizophrenia.
- If a patient has a history of _________ with psychosis, but no current psychotic symptoms, ketamine may be a treatment option but the patient should be carefully monitored.
Major depressive disorder,
- Ketamine may be used to treat postpartum depression and is safe for women who are breastfeeding
True.
- Which of the following does Dr. Amato recommend when administering ketamine treatments with PTSD?
Exercising caution with patients with big trauma history, ensuring a therapist is involved for preparation and integration and starting with an oral dose.
- Dr. Amato recommends exercising caution when administering ketamine treatments to patients who have ___________.
Migraines and seizure disorders.
- Letting patients with trauma history know they may re-experience trauma with defenses lowered during ketamine treatment is part of the _______.
Informed consent discussion.
- Which of the following are potential stressors to assess prior to ketamine treatment?
Work problems, recent losses, family and relationship problems and legal issues.
- Meditation and mindfulness practices aim to help individuals to:
Become more aware, become more present and widen their capacity to hold multiple points of awareness simultaneously.
- The core intention of meditation and mindfulness practices is to calm down and not have thoughts.
False.
- __________ are ways that human beings interface with the world, and refers to how much complexity we are able to take in.
The three gates (body, speech, mind).
- Asking someone with trauma to pay close attention to their inner world can sometimes mean coming into contact with traumatic stimuli.
True.
- Which of the following may support the establishment of a daily meditation practice?
Apps and tracking progress, making a beautiful space to meditate, seek instruction, meditate on the spot, even for 30 seconds.
- For clients with complex PTSD, Dr. Lewis recommends first focusing on ___________.
Exteroception.
- The study design of the FDA Phase 3 trials with MDMA for PTSD consists of four phases: screening, three preparation sessions, 9 integration therapy sessions, and a two month follow up.
True.
- The most frequent non-serious adverse events for those that were in the MDMA trial group were:
Muscle tightness and decreased appetite.
- The FDA will not require a pediatric study with MDMA.
False.
- There will be a future dose response safety study with MDMA concerning which types of pharmaceutical drugs?
SSRI’s.
- According to Dr. Doblin, studies on MDMA in the late 90s and early 2000s claimed that it damaged dopamine and serotonin receptors. However, these studies were actually using __________ in their studies, not MDMA.
Methamphetamine.
- Third party payers such as insurance companies can expect to save money with MDMA assisted therapy within ____________.
3 years.
- “Classic” psychedelics, such as LSD, psilocybin are:
Serotonin 2a receptor agonists.
- Activation of the Serotonin 2A receptors enhances:
Learning rates, plasticity, synaptogenesis and neuroplasticity markers.
- According to Dr. Carhart-Harris, various cortexes of the brain seem to “talk” to each other while on psychedelics such as psilocybin and LSD.
True.
- Psilocybin “flattens” the brain’s landscape, making it easier for patients to experience diversity of thought and healthier flexibility of thoughts.
True.
- In a study comparing psilocybin to the SSRI escitalopram, it was found that psilocybin increased participants:
Ability to cry and feelings of pleasure.
- According to Dr. Carhart-Harris, neuroplasticity increases were observed after __________ of psilocybin.
3 months.
- According to Dr. Watts, psychological flexibility is the result of:
Acceptance and connectedness.
- The ACE model stands for Accept, Connect, and Encompass.
False
- In applying the ACE Model in your own work, Dr. Watts recommends:
Writing your own preparation structure in line with ACE, Write your own visualization, Record audios of the visualization for yourself or others, play around with the six principles for designing prep, session, and integration protocols.
- Psychological photosynthesis, according to Dr. Watts, is the process of transmuting suffering into growth
True.
- According to Dr. Watts in the study she ran in 2017 on psilocybin, participants described the majority of their depression as a sense of disconnection.
True.
- According to Dr. Watts there are _______ key areas in psychological flexibility.
Six.
- According to Sara Gael, even though they are human synthesized, MDMA and ketamine still have _________ that it is important to be knowledgeable about it if you choose to work with them in therapy.
Lineage.
- The __________ one brings to the field of psychedelic assisted therapy is informed by the mentors and teachers in one’s life.
Perspective.
- Someone’s own personal identity may inform the populations they wish to work with in the psychedelic field
True.
- ____________ impacts the location where an individual is able to practice with a specific medicine.
Legality and regulation.
- Which of the following are examples of a setting where someone may work in the psychedelic field:
University, research, private practice, retreats.
- Which of the following does Sara Gael consider to be adjacent to psychedelic-assisted therapy?
Drug policy and advocacy, harm reduction and art.
- According to Dr. Van Derveer, integrative psychiatry is the process of:
Attending to bio-psycho-social-spiritual aspects of wellness, resolving root causes, seeing health on a continuum as opposed to pathology.
- Integrative psychiatry is only of relevance to psychiatrists, not therapists.
False.