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Psych Shelf Flashcards

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1
Q

Risperidone side effects?

A 
(serotonin & dopamine antagonist)
postural hypotension
movement disorders (esp. extrapyramidal withdrawl syndrome)
increased prolactin
weight gain
sedation
decreased concentration
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2
Q

carbamazepine side effects?

A

aplastic anemia
SIADH
agranulocytosis
teratogenic (craniofacial defects)

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3
Q

pneumonic for major depressive disorder?

A 
S- sleep disorder
I- loss of interest
G- guilt
E- loss of energy
C- poor concentration
A- loss of appetite
P- psychomotor retardation or agitation
S- suicidality

At least 5 of these everyday for 2 weeks + depressed mood

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4
Q

First line treatment for specific phobia?

A

behavioral therapy

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5
Q

Which drugs have side effects of diabetes/hyperlipidemia/metabolic syndrome?

A

atypical antipsychotics - clozapine, risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole

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6
Q

What’s an erotomaniac delusion?

A

False belief that someone is in love with you

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7
Q

treatment for extrapyramidal symptoms d/t antipsychotics?

A

anti-cholinergics - benztropine

or diphenhydramine

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8
Q

What is akathisia and what’s the treatment?

A

Akathisia = “inability to sit;” restlessness seen most commonly with high-potency typical antipsychotics (haloperidol & chlorpromazine)

Treatment = beta-blocker (propanolol is the best) -> think inability to sit is like inhibition of parasympathetic system so give beta-blocker to turn off the sympathetic branch a little

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9
Q

Treatment for pediatric OCD?

A

1- cognitive behavioral therapy
2- serotonergic reuptake inhibitors
-> SSRIs (fluoxetine, fluvoxamine, sertraline) or clomipramine (a TCA that inhibits serotonin & NE reuptake)

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10
Q

Treatment for negative symptoms of schizophrenia?

A

Olanzapine & Clozapine

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11
Q

Which antidepressants affect warfarin metabolism?

A

sertraline, paroxetine, fluvoxamine

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12
Q

pharmacotherapy for Tourette’s?

A

dopamine antagonists -> fluphenazine, pimozide, haloperidol

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13
Q

Thioridazine side effects?

A

QT prolongation

retinitis pigmentosa

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14
Q

Olanzapine side effects?

A 
orthostatic hypotension
increased prolactin
anticholinergic
weight gain
somnolence
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15
Q

Side effects of all TCAs

A
  • anticholinergic: dry mouth, blurry vision, urinary retention, constipation, sedation,
  • Anti-alpha: orthostatic hypotension, tachycardia
  • QT prolongation
  • weight gain
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16
Q

Which antidepressant can also treat ADHD?

A

buproprion

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17
Q

What’s the concordance rate for mood disorders (like depression) in identical (homozygotic) twins?

A

90%

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18
Q

lifetime risk of suicide in mood disorders?

A

10-15%

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19
Q

Best antidepressant atypical depression?

A

MAOi

20
Q

Best antidepressant for melancholic depression?

A

TCAs

21
Q

What are the CAGE questions?

A

Have you ever felt the need to CUT down on drinking?
Have you ever felt ANNOYED by criticism on your drinking?
Have you ever felt GUILTY about drinking?
Have you ever had to take a morning EYE-OPENER?

> 1 Yes = alcoholism likely

22
Q

Acronym for personality disorders?

A 
M- maladaptive
E- enduring
D- deviates from norm
I- inflexible
C- causes impaired social functioning
23
Q

Cluster A personality disorders

A

WEIRD

  • Paranoid - perceive attacks on self that are not apparent to others
  • Schizoid - social isolation; cold & detached
  • Schizotypal - magical thinking; “out-of-body” perceptual experiences
24
Q

Cluster B personality disorders

A

WILD

  • Borderline - impulsive; unstable; labile moods; lots of SI; chronic feelings of emptiness
  • Histrionic - need to be “center of attention;” provocative
  • Narcissistic - grandiosity about self; lack of empathy
  • Antisocial - impulsive; deceitful; lack of remorse; failure to conform to social norms/lawful behavior
25
Q

Cluster C personality disorders

A

WORRIED/WIMPY
Obsessive-compulsive - needs control; perfectionist; inflexibility of morals and values
Avoidant - excessive shyness; hypersensitive to rejection; fears being disliked or ridiculed
Dependent - submissive; clingy; can’t be alone

26
Q

Somatization Disorder

A
  • Begins before age 30
  • lasts several years
  • 1% prevalence
  • 5:1 Female:Male
  • 4 pain symptoms, 2 GI, 1 sexual, 1 pseudoneurologic

*Tx: psychotherapy; regular, brief PCP visits

27
Q

Conversion Disorder

A
  • neurologic complaint
  • symptoms are NOT feigned
  • patient is indifferent -> la belle indifference

*Tx: anxiolytics; can spontaneously remit

28
Q

Hypochondriasis

A
  • worry/fear of having a serious disease
  • > 6 months
  • onset usually 20-30 yo

*Tx: group therapy; frequent reassurance

29
Q

Pharmacotherapy for GAD?

A

SSRIs
imipramine (a TCA)
buspirone

30
Q

Treatment for TCA overdose?

A

sodium bicarbonate

31
Q

3 “C”s of TCA toxicity?

A

Convulsions
Coma
Cardiac arrhythmias

32
Q

anaclitic depression

A

AKA hospitalism
from Rene Spitz
infants that are emotionally deprive can fail to thrive

33
Q

absolute contraindication to buproprion?

A

seizure disorder (buproprion can lower the seizure threshold)

34
Q

main nucleus releasing NE?

A

locus ceruleus!

  • in pons near 4th ventricle and para-cerebral aqueduct
  • involved in physiologic response to stress/panic
  • hyperactivity here could be part of PTSD symptoms
35
Q

function of nucleus basalis of Meynert?

A
  • associated with memory formations
  • supplies ACh
  • degenerates in Alzheimer’s
36
Q

function of nucleus accumbens?

A
  • associated with reward and addiction

* supplies serotonin

37
Q

dystonic reaction? What is it & how to treat.

A
  • due to neuroleptics (high potency, like haloperidol)
  • sustained spasmodic contraction -> like torticulous
  • treat with diphenhydramine
  • usually occurs within 3 days of beginning treatment
  • more common in men
38
Q

Broca’s area?

A
  • located in left lateral frontal lobe
  • lesion = normal comprehension; inability to speak
  • usual deficit due to left middle cerebral artery stroke
39
Q

origin of partial complex seizures?

A
  • temporal lobe

* usually start with bad odor

40
Q

anterior nucleus of hippocampus?

A

sexual behavior

lesion = suppressed sexual interest

41
Q

ventromedial nucleus of hippocampus?

A

satiety center for appetite

lesion = get fat

42
Q

lateral nucleus of hippocampus?

A

stimulates appetite

lesion = anorexia

43
Q

posterior nucleus of hippocampus?

A

works with RAS to control arousal

lesion = lethargy & somnolence

44
Q

supraoptic & paraventricular nuclei of hippocampus?

A

produce ADH & oyxtocin -> neurons take these to the posterior hypothalamus

45
Q

Most worrisome side effects of clozapine?

A

agranulocytosis

seizure

46
Q

neuroleptics causing photosensitivity?

A

low-potency typicals - esp. chlorpromazine

47
Q

blood alcohol level at which most people have slurred speech/memory impairment/blackout

A

200-300 mg/dL

Psych (1 decks)

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