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EOR psych meds > psych meds > Flashcards

psych meds Flashcards

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1
Q

Severe acute mania is treated with?

A

Lithium or Valproate in addition to antipsycotic

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2
Q

Mild to moderate mania treated with?

A

risperidone or olanzapine monotherapy

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3
Q

what is the theraputic window for Lithium?

A

0.8-1.2 mEq/L

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4
Q

Lithium is known to decrease what organ function?

A

Kidney function over time

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5
Q

what meds will increase lithium levels?

A

ACEI, NSAIDs, thiazides, tetracycline and metro

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6
Q

pharmacological treatment for obsessive compulsive disorder is?

A

SSRIs: sertraline, fluoxetine, fluvoxamine, paroxetine, citalopram, escitalopram

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7
Q

how long should pts with OCD and a positive response stay on pharm therapy?

A

1 year

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8
Q

Black box warning for Valproate?

A

Hepatotoxicity, pancreatitis

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9
Q

what is 1st line tx for lowering BP in amphetamine intoxication?

A

Lorazepam

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10
Q

what antidepressant med can cause a faulse positive for amphetamines on urine drug?

A

bupropion

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11
Q

1st line therapy for social anxiety disorder?

A

SSRI: paroxetine

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12
Q

1st line tx in illness anxiety disorderd?

A

cognitive behavioral therapy

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13
Q

management of avoidant personality disorder?

A

psycotherapy(cognitive behavior therapy and social training), Pharm therapy can be used in adjunct.

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14
Q

Zolpidem is what? and used to tx what?

A

Nonbenzo benzodiazepine, insomnia

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15
Q

MOA of benzos

A

GAba agonits

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16
Q

MC manifestation of cannabis withdrawl?

A

disturbed sleep

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17
Q

Meds that can be used in tx sleep-related disturbances after cessation of cannabis?

A

Zolpidem and nitrazepam

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18
Q

what are some atypical anti-dp

A

mirtazapine, bupropion, agomelatine

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19
Q

what are some SNRIs

A

duloxetine, venlafaxine

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20
Q

MAOIs

A

phenelzine, isocarboxazid

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21
Q

tx for ADHD pts with substance abuse Hx?

A

Atomoxetine(little to no abuse potential)

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22
Q

Toluene is a type of what?

A

inhalant (it is a volital solvent)

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23
Q

what can be found in urine drug screen after the use of Toluene?

A

hippuric acid

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24
Q

what is the MOA by which varenicline helps reduce nicotine withdrawl?

A

it is a partial agonist at the alpha 4 beta 2 nicotinic receptor

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25
Q

what med should be monitored to identify low serum bicarb?

A

topiramate

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26
Q

post pardum depression tx?

A

sertraline, paroxetine, fluvoxamine (safe in breastfeeding)

27
Q

can buproprion be used for smoking cessatipn in prego pts?

A

NOPE!

28
Q

appropriate tx for acute ETOH with drawl?

A

IV benzos, IV fluids

29
Q

Clozapine can cause?

A

agranulocytosis

30
Q

tx for pts that are going thru cannabis withdrawl and have s/s that are affect their work/life?

A

dronabinol or gabapentin

31
Q

Amantadine is?

A

nonanticholinergic antiparkinsonian med. can be used in treat parkinsonian extrapyramidal side effects caused by antipsycotic meds

32
Q

what meds are 1st gen antipsycotics?

A

chlorpromazine, haloperidol, perphenazine, thioxthixene

33
Q

what is alprostadil?

A

arterial smooth muscle relaxor that can be injected into the penis to cause an erretionc

34
Q

the acute phase of dystonic reaction may be treated with?

A

diphenhydramine(benzotrpine can alos be used)

35
Q

what is the best clinical intervention for conduct disorder?

A

multisystemic treatment

36
Q

treatment for cyclothymic disorder?

A

mood stabilizer: lithium or antipsycotics

37
Q

what are the two MC side effects of mirtazapine?

A

wt gain, sedation

38
Q

what is 1st line therapy for treatment of bipolar major depression?

A

quetiapine or lurasidone

39
Q

what SSRI increases the QTc interval the most?

A

Citalopram

40
Q

Which antipsycotic most commonly causes wt gain?

A

Olanzapine

41
Q

Ziprasidone is a second gen antipsychotic that carries high risk for?

A

QT prolongation

42
Q

what is the antidote for benzo intoxication?

A

flumazenil

43
Q

1st line pharm for binge eating disorder?

A

SSRIs, topiramate, lisdexamfetamine

44
Q

which two alpha-2 adrenergic agonists may be used to treat impulsivity in conduct disorder?

A

guanfacine and clonidine

45
Q

what is an alternitive med for ADHD tx?

A

Atomoxetine ( nonstimulant med, s/e: n/v, wt loss, QT prolongation)

46
Q

prenatal exposure to what agent is consistently associated with the development of attention-def/hyperactivity disorder?

A

tobacco

47
Q

anorexia pts have an increase or decrease in total WBCs?

A

decrease (leukopenia)
normochromic and normocytic anemias are also seen

48
Q

what is the MOA for first gen antipsychotics?

A

blockage of dopamine D2 receptors at the postsynaptic membrane

49
Q

which of the following clinical therapys would be most sedaating?
cilatopram
fluoxetine
paroxetine
sertraline

A

paroxetine

50
Q

what SSRI is associated more commonly with n/v?

A

fluvoxamine

51
Q

what second gen antipsycotic is known to cause elevated serum prolactin levels?

A

risperidone

52
Q

what is Divalproex?

A

anticonvulsant, used to treat sz and bipolar disorder

53
Q

in pts with severe aggrestion what medications are indicated for pharm treatment?

A

second gen antipsycotic: risperidone or quetapine

54
Q

medication for difficulty maintaining sleep?

A

long acting nonbenzo receptor agonists, dual orexin receptor antagonists and histaimne receptor antagonists (doxepin)

55
Q

sleep initiation med

A

ramelteon

56
Q

which antihypertensive medications are sometimes used in the tx of PTSD?

A

alpha blockers and clonidine

57
Q

which teratogenic anticonvulsant has been linked to autism spectrum disorder?

A

valproate

58
Q

what medication is contraindicaded in treating cocain induced HTN?

A

propranolol due to unopposed alpha constriction

59
Q

what are s/e of benzotropine?

A

anticholinergic s/e

60
Q

what are the s/e of clonidine?

A

sedation, depression, bradycardia, HA, hypotension

61
Q

what is 1st line pharm therapy for bulimia?

A

fluoxetine(most studied)

62
Q

what is 1st line tx for neuropathic ppain?

A

duloxetine

63
Q

what is the black box warning for duloxtetine?

A

increased risk of suicidal thoughts and behavior in peds and young adults

64
Q

what pharm tx of schizotypal personality disorder is aimed at disordered thinging and inattention>

A

Quetapine

EOR psych meds (1 decks)

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