psych last min

Question 1

Which cause of dementia are these assoc w:

• emotional lability?
• apathetic mood?
• agnosia?
• pseudobulbar palsy?
• short stepping gait?

Answer 1

• Pick’s
• LBD
• Alzheimers
• Vascular (also seen in parkinson’s, supranuclear palsy and MS)
• vascular

Question 2

Alzheimers?

Answer 2

• word finding problems
• depression etc
• delusions
• paranoia
• insomnia

Executive function and personality preserved until late

Question 3

Echolalia is a feature of which dementia?

Answer 3

Frontotemporal

Question 4

What apo gene is a RF for alzheimers?

Which is protective

Answer 4

RD - ApoE4

Protective - ApoE2

Question 5

Prader willi?

Answer 5

chr 15, paternally derived

eating, reckless, LD

Question 6

Angleman?

Answer 6

chr 15 maternally derived

ataxia - puppet like movements and paroxysms of laughter

Question 7

DiGeorge?

Answer 7

deletion of 22Q

small head, heart defect, prominent nose

Question 8

cri du chat?

Answer 8

chr 5

microcephaly cry like cat

Question 9

lesch nylan?

Answer 9

x linked, purine metabolism

gout, renal stones, characteristically biting to hurt self

Question 10

Which alcohol withdrawal drug is 1st line and reduces reward (opioid antagonist)?

Answer 10

Naltrexone

Question 11

Alcohol withdrawal:

• Acamprosate?
• Disulfiram?

Answer 11

acts on GABA/glutamate, reduces cravings

Inhibits aldehyde dehydrogenase

Question 12

Appetitive?

Answer 12

seeking and approach behaviours inc pleasure - dopamine

Question 13

Aversive?

Answer 13

survival and threat, fear, pain - serotonin

Question 14

Orbito-frontal cortex?

Prefrontal cortex?

Answer 14

motivation to act

Inhibition and keeping impulses under control