Psych IV

Question 1

narcolepsy

Answer 1

disordered regulation sleep wake cycle

excess daytime sleepiness

decreased hypocretin - orexin - lateral hypothalamus

cataplexy - loss muscle tone following emotional stimulus

genetic component

Question 2

tx narcolepsy

Answer 2

daytime stimulant - amphetamine,modafinil

nighttime sodium oxybate - GHB

Question 3

substance use disorder

Answer 3

maladaptive pattern of substance use 2 or more in 1 year:

• tolerance
• withdrwal
• substance taken larger amounts than desired
• persistent desire and inability to cut down
• loss social, occupational, recreational activity
• craving
• failure fulfill social role

Question 4

stages of change overcoming substance addiction

Answer 4

1 - precontemplation - don’t know problem
2 - contemplation - acknowledge there is problem
3 - preparation/determination - getting ready to change
4 - action/willpower - change behavior
5 - maintenance - maintain behavior change
6 - relapse - to old behavior

Question 5

serum GGT

Answer 5

indicatory of alcohol use

Question 6

alcohol

Answer 6

AST 2x ALT

Question 7

flumazenil

Answer 7

benzo antagonist

-rarely used - precipitate seizures

Question 8

amphetamine use

Answer 8

cardiac arrest

seizure

Question 9

cocaine use

Answer 9

pupil dilation, hallucination, paranoid, angina, cardiac death sudden

tx - a-blocker, benzo

B-blocker - not recommended

Question 10

tx nicotine

Answer 10

bupropion

varenicline

Question 11

buprenorphine

Answer 11

partial agonist opioid receptor

used for heroin addict

Question 12

methadone

Answer 12

long acting oral opiate

Question 13

PCP

Answer 13

impulsive, fever, psychomotor, analgesia, nystagmus, tachy, homicideality, psychotic

tx - benzos and antipsychotic

Question 14

marijuana

Answer 14

antiemetic for chemo
appetite stimulant in AIDS

pharm form - dronabinol

Question 15

disulfiram

Answer 15

anabuse

Question 16

wernicke korsakoff

Answer 16

vit B1 deficient

wernicke encephalopathy - confusion, ophthalmoplegia, ataxia

korsakoff - personality change, memory loss

tx - vit B1

Question 17

mallory weiss syndrome

Answer 17

partial thickness tear GE junction

Question 18

delirium tremens

Answer 18

life threatening alcohol withdrawal syndrome
-2-4 days after last drink

autonomic hyperactive
in alcoholic not able to drink in hospital

tx - benzos