Psych Final Medications Flashcards by Jacki Leigh

What is Fluoxetine?

Brand Name: Prozac
SSRI

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What is Sertraline?

Brand Name: Zoloft
SSRI

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What is Paroxetine?

Brand Name: Paxil
SSRI

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What is Citalopram?

Brand Name: Celexa
SSRI

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What is Escitalopram?

Brand Name: Lexapro
SSRI

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What is Fluvoxamine?

Brand Name: Luvox
SSRI

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What are the symptoms of Serotonin Syndrome?
(Both Mild and Severe)

Minor: Chills, Diarrhea
Severe: Muscle Rigidity, Fever and Seizures-can be fatal

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What is Prozac (Fluoxetine) used to treat?

MDD, MCD, Bulimia, Panic Disorder, PTSD, Premenstrual Dysphoric disorder

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What are the 4 SNRIs?

Venlafaxine (Effexor)
Desvenlafaxine (Pristiq)
Duloxetine (Cymbalta)
Levomilnacipran (Fetzima)

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What is Venlafaxine?

Brand Name: Effexor
SSNRI

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What is Desvenlafaxine?

Brand Name: Pristiq
SSNRI

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What is Duloxetine?

Brand Name: Cymbalta
SSNRI

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What is Levomilnacipran?

Brand Name: Fetzima
SSNRI

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What are the 4 SARIs?

Serotonin Antagonists and retuptake inhibitors
Nefazodone (Serzone)
Brexipiprazole (Resulti)
Vilazodone (Viibryd)
Vortioxetine (Trintellix)

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What is Mirtazpine?

Known as the Brand Name Remeron, it is a norepinephrine and serotonin specific antidepressant

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What are the Tricyclic antidepressants?

Nortriptyline (Pamelor)
Amitriptyline (Elavil)*
Imipramine (tofranil)*
*prototypes

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What are the adverse effects of the Tricyclic Antidepressants?

Sedation
Orthostastic Hypotension
Anticholinergic Effects
Cardiotoxicity
Sexual Dysfunction

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What are the MAOIs?

Isocarboxazid (Marplan)
Phenelzine (Nardil)
Selegiline (EMSAM)
Tranylcypromine (Parnate)

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What are the symptoms of a HTN crisis caused by the ingestion of tyramine while taking an MAOI?

Severe Headache
Tachycardia
Nausea/Vomiting
Confusion
Diaphoresis
CVA
Death

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What are the first generation dopamine antagoinsts?

Chlorpromazine (Thorazine)*
Haloperidol (Haldol)
Thioridazine (Mellaril)
Loapine (Loxitane)
Pherphanazine
Fluphenazine (Prolixin)
Pimozide (Orap)
Thiothixene (Navane)
Trifluoperazine

*Prototype

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What are the side effects of first generation antipsychotics?

Extrapyramidal side effects
Anticholinergic side effects
Tardive Dyskinesia
Weight gain
Sexual Dysfunction
Endocrine Disturbances

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What are the second generation serotonin and dopamine antagonists?

Clozapine (Clozaril)
Risperidone (Risperidal)

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What symptoms of schizophrenia do second gen antipsychotics treat?

Both positive and negative symptoms, while first generation only treat positive

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What are the adverse effects of 2nd generation antipsychotics?

Minimal to no EPS/TD
Tendancy to cause weight gain, diabetes, dyslipidemia, risk of metabolic syndrome, sexual dysfunction

What are the 'Third generation' Antipsychotics?

Aripiprazole (Abilify) Brexpiprazole (Rexulti) Cariprazine (Vraylar)

What are the benefits of 'Third generation' antipsychotics?

Since they are dopamine system stabilizers, they may improve positive, negative and cognitive function with little risk of EPS or tardive dyskinesia

What are the potentially dangerous side effects to antipsychotics?

ACh toxicity-Antidote Physostigmine Neuroleptic maliganant syndrome Agranulocytosis Prolonged QT interval (FGA/SGA) Liver impairment

Which first generation antipsychotic is used for a long acting injection from every 3-6 weeks?

Fluphenazine (Prolixin)

What is dystonia?

An extrapyramidal symptom that causes spasms of the tongue, face, neck, back, and upward eyes

What is akathisia?

Compulsive, restless movement, anxiousness, agitation, onset in 5-60 days

What is the treatment options for Akathisia?

Benzodiazepines Beta blockers Anticholinergics

What are the symptoms of pseudoparkinsonism?

Bradykinesia Masked Face Tremors Rigidity Shuffle Drooling

What are the treatment options for psuedoparkinsonsim?

Cognetin Benadryl Amantadine

What is the treatment for Tardive Dyskinesia?

Benzodiazapines and switch to 2nd gen

What are the symptoms neuroleptic malignant syndrome?

Rigidity High Fever Diaphoresis Autonomic Instability Dysrhythmias Change in LOC Seizures Coma Respiratory Failure

What is the treatment for neuroleptic malignant syndrome?

Dantrolene/Dentrium (IVP-1min) Bromocriptine/Parlodel

What are the therapeutic levels for Lithium Carbonate?

0.8 to 1.4 mEq/L

What are the maintenance levels for lithium carbonate?

0.4 to 1.3 mEqL

What are the toxic blood levels for lithium carbonate?

1.5 mEq/L and above

What should you be monitoring when a patient is taking Lithium?

Thyroid Kidneys (Polyuria, Na/Li reabsorption) Sinus bradycardia Tremors (indicates toxicity)

What should you monitor for a patient that is taking Valproate?

Blood Levels Liver Enzymes Platelets

What should you be monitoring for in a patient taking carbamazepine?

Blood Levels Liver Enzymes Aplastic Anemia

What should you be monitoring for in a patient taking Lamotrigine?

Rash->indicates Steven Johnson syndrome/toxic epidermal nercolysis

What is Clonazapam?

Brand Name: Klonopin Anxiolytic

What is Lorazepam?

Brand Name: Ativan Anxiolytic

What are the cholinesterase inhibitors that work to delay cognitive decline for mild/moderate stage of Alzheimer's?

Donepezil HCL (dissolving tabs, solution) Rivastigmine (solution, patch) Galantamine

What is the NMDA receptor antagonist that is used for cognitive decline in the moderate/severe stage of Alzheimer's?

Memantine (Namenda)

What types of drugs should not be used/used with caution in neurocognitive disorders?

Black box warning: Atypical Antidepressants Use caution with: Benzos, opioids, anticholingergics

What are the 4 different types of benzodiazepines?

Diazepam (Valium) Clonazepam (Klonopin) Alprazolam (Xanax) Lorazepam (Ativan)

What are the short acting stimulants?

Methylphenidate (Ritalin) Dexmethylphenidate (Focalin) Amphetamine/Dextroamphetamine (Adderall)

What are the long acting stimulants?

Lisdexamphetamine (Vyvanse) Daytrana (Methylphenidate patch) Quillichew ER, XR (M.P chewable/liquid) Jornay PM (M.P taken at night)

What are the non-stimulant medications for ADHD that are alpha 2 adreneric agonists?

Guanfacine (Tenex, intuniv) Clonidine (Catapres, Kapvay)

What is the treatment for opioid overdose?

Naloxone (Narcan) IV, sub-q, IM, nasal spray

What is the oral opioid agonist that is used for maintenance of opioid addiction that can cause dependence?

Methadone

What is buprenorphine (subutex)?

A sublingual partial opioid agonist/antagonist that is used to treat opioid addiction

What is Naltrexone?

Brand Name: Vivitrol, Revia Opioid Antagonist that is used in the prevention of relapse because it blocks the euphoric and sedative effects

What is the treatment for benzodiazepine overdose?

IV flumazenil (Romazicon)

What is Acamprosate calcium (Campral)?

A drug used for maintenance of alcohol abstience in patients that are abstinent at treatment initiation and reduves insomnia, anxiety and restlessness