Psych Exam 2 Flashcards
WARNING: topics include suicide, mood disorders, intimate partner violence and abuse, and more
What type of anti-psychotics target positive symptoms?
Conventional (first-generation)
What type of anti-psychotics target positive and negative symptoms?
Atypical (second-generation)
How do anti-psychotic medications work against schizophrenia?
Alleviate the symptoms but do not cure the underlying psychotic processes
Can return with medication noncompliance
What are some reactions of anti-psychotic medications?
Anti-cholinergic effects
Orthostasis
Lowered seizure threshold
What is schizophrenia and what does it affect?
Brain disorders affecting thinking, language, emotions, social behavior ability to perceive reality accurately
Psychosis
Symptom; refers to a total inability to recognize reality
not a diagnosis
Ongoing psychosis
Never fully recovering
Episodes of psychotic symptoms
Alternating episodes of relatively complete recover
Long-term course of psychosis
Intensity diminishes with age and the disease becomes less disruptive
What are the co-morbidities of schizophrenia?
Substance abuse disorders
Anxiety
Depression
Suicide
Physical health illness
Polydipsia
What factors may play a role in the etiology of schizophrenia?
Genetic
Brain structure abnormalities (less brain tissue and CSF)
Neurobiological theories (elevated dopamine, serotonin, and glutamate)
Immunovirologic factors
What are the psychological and environmental factors which play a role in the etiology of schizophrenia?
Prenatal stress
Psychological stressors
Environmental stressors
What can be seen in imaging results of patients with schizophrenia?
Enlarged ventricles
Smaller brains
Less grey matter
Less brain mass
Higher density of dopamine receptors
What five items are included in the DSM for schizophrenia?
Delusions
Hallucinations
Disorganized speech
Grossly disorganized or catatonic behavior
Negative symptoms
What are examples of positive (hard) symptoms found in schizophrenia?
Delusions, hallucinations, hyper-vigilance
What are the examples of negative (soft) symptoms of schizophrenia?
Flat effect, lack of volition, inattention
What are alterations in thinking in schizophrenia?
Impaired reality testing
Delusions
Concrete thinking
What are alterations in speech in schizophrenia?
Associative looseness
Neologisms
Clang association
Word salad
Echolalia
Echopraxia
What are alterations in perception in schizophrenia?
Depersonalization
Hallucinations
Illusions
Command hallucinations
Derealization
What are alterations in behavior in schizophrenia?
Bizarre behavior
Extreme motor agitation
Stereotyped behaviors
Waxy flexibility
Stupor
Negativism
Automatic obedience
Impulse control resulting in agitated behaviors
What are therapeutic strategies for communicating with patients with schizophrenia?
Lower anxiety
Decrease defensive patterns
Encourage participation in therapy and social events
Raise feelings of self-worth
Increase medication compliance
Tardive dyskinesia
irreversble
Seen more in long-term usage of conventional anti-psychotics
Involuntary rhythmic stereotyped movements of trunk and extremities
Symptoms increase with anxiety and tension
Extrapyramidial syndrome
Reversible and can be treated with anti-cholinergics
Characterized by: pseudoparkinsonism,acute dystonia, and akathesia
Treatment: anti-parkinsonian drugs and lowered doses
What falls under pseudoparkinsonism?
Stiffness/rigidity, tremors, drooling, pill rolling, mask-like experience, thick tongue, cog wheeling
What falls under acute dystonia?
Irregular, involuntary abnormal positioning of the neck, head, arms, legs, and trunk
Oculogyrc crisis
Akathesia
Motor restlessness
What is the purpose of antipsychotic medications?
Alleviate symptoms of schizophrenia (not a cure)
symptoms will return if discontinued
What are common reactions with antipsychotic medications?
Anticholinergic effects
Orthostasis
Lowered seizure threshold
What do conventional (first-generation) antipsychotics target?
Positive symptoms
What do atypical (second-generation) antipsychotics target?
Positive and negative symptoms
Why are atypicals often preferred compared to conventional antipsychotics?
Fewer side effects and target more symptoms
What are some examples of conventional antipsychotic medication?
Thiothixene [Navane]
Fluphenazine [Prolixin]
Haloperidol [Haldol]
Pirozide [Orap]
Loxaine [Loxitane]
Molidone [Moban]
Perphenazine [Trilafon]
Chlorpromazine [Thorazine]
Thioriadizine [Mellaril]
What are some examples of atypical antipsychotic medications?
Aripiprazole [Abilify]
Clozapine [Clozaril]
Olanzapine [Zyprexa]
Paliperidone [Invega]
Quetiapine [Seroquel]
Risperidone [Risperdal]
Ziprasidone [Geodon]
What six antipsychotic medications are available in the form of depot injections?
Fluphenazine
Haloperidol
Risperidone
Paliperidone
Olanzapine
Aripiprazole
What is metabolic syndrome characterized by?
Hyperglycemia, dyslipidemia, and abdominal obesity
What labs should you look at in metabolic syndrome? Interventions?
CBC, serum glucose level, lipid panel, liver function, vision tests
Need baseline bloodwork and regular monitoring; check family history of metabolic disorders
What drugs seem to have the highest risk with metabolic syndrome?
Clozaril and Zyprexia
What are the side effects and adverse reactions of antipsychotics seen more in first-generation medications?
Extrapyramidal symptoms (EPS) and tardive dyskinesia (TD)
What are the side effects and adverse reactions of antipsychotics seen more in second-generation medications?
Metabolic syndrome
What is neuroleptic malignant syndrome?
fatal
Usually occurs suddenly and symptoms can be mistaken for an illness of other side effects
Altered consciousness (confusion and irritability)
Muscle rigidity and abnormal blood work
Should medication continue to be administered, or should it be held in a patient experiencing neuroleptic malignant syndrome?
Hold medication
What is a fairly common adverse reaction to Clozapine [Clozaril] in patients?
Agranulocytosis
What is agranulocytosis?
Bone marrow is unable to produce sufficient amounts of WBCs which leads to fever, malaise, sore throat, and leukopenia
Interventions: regular bloodwork (WBCs over 3500)
_____ are administered for severe depression.
Antidepressants
_____ and other _____ _____ reduce aggressive behaviors.
Hint: medications
Lithium
Mood stabilizers
_____ _____ improves positive and negative symptoms.
Benzodiazepine augmentation
OR atypical second gen anti-psychotics
_____ decreases anxiety, agitation, and possibly psychosis.
Clonazepam
According to evidence-based psychosocial therapies, family needs to be included in:
Psychologic strategies aimed at reducing psychotic symptoms
Teaching patient and family about illness
Recognizing effect of stress
Identifying support sources
Medication groups for patients and family
Schizoaffective disorder
Diagnosed when a client is severely ill and has a mixture of psychotic and mood symptoms
These symptoms can occur simultaneously or alternating
Schizophreniform disorder
The client exhibits an acute, reactive psychosis for less than 6 months necessary to meet the diagnostic criteria for schizophrenia
Catatonia
Characterized by marked psychomotor disturbance, either excessive motor activity or virtual immobility and motionlessness
Delusional disorder
The client has one or more non-bizarre delusions (believable)
Delusions may be persecutory, erotomanic, grandiose, jealous, or somatic in content
Brief psychotic disorder
The client experiences the sudden onset of at least one psychotic symptom which last from one day to one month
Symptoms include delusions, hallucinations, or disorganized speech or behavior
Shared psychotic disorder (folie à deux)
Two people share the same delusion after one begins to mimic the delusions of the other
Schizotypal personality disorder
This involves odd, eccentric behaviors - includes transient psychotic symptoms
Dysthymic disorder
A chronic, persistent mood disturbance characterized by symptoms such as insomnia, loss of appetite, decreased energy, low self-esteem, difficulty concentrating, and feelings of sadness and hopelessness
Disruptive mood regulation disorder
A persistent angry or irritable mood, punctuated by severe, recurrent temper outbursts that are not keeping with the provocation or situation
Begins before the age of 10
Cyclothymic disorder
Characterized by mild mood swings between hypomania and depression without loss of social or occupational functioning
Substance-induced depressive or bipolar disorder
Characterized by a significant disturbance in mood that is a direct physiological consequence of ingested substances such as alcohol, other drugs, or toxins
Seasonal affective disorder (SAD) - winter depression or fall onset
Increased sleep, appetite, and carbohydrate cravings
Weight gain, interpersonal conflict, irritability, and heaviness in the extremities beginning in late autumn and abating in spring and summer
Seasonal affective disorder (SAD) - spring onset
Less common
Symptoms of insomnia, weight loss, and poor appetite lasting from late spring or early summer until the fall
Postpartum or “maternity” blues
Mild, predictable mood disturbance occurring in the first several days after delivery of a baby
Symptoms include labile mood and affect, crying spells, sadness, insomnia, and anxiety
Postpartum depression
Symptoms are consistent with those of depression with onset within 4 weeks of delivery
Postpartum psychosis
A severe and debilitating psychiatric illness, with acute onset in the days following childbirth
Symptoms begin with fatigue, sadness, emotional lability, poor memory, and confusion
Progresses to delusions, hallucinations, poor insights and judgment, and loss of contact with reality
Premenstrual dysphoric disorder
A severe form of premenstrual syndrome
Defined as a recurrent, moderate psychological and physical symptoms that occur during the week before menses and resolving with menstruation
Non-suicidal self-injury
Involves deliberate, intentional cutting, burning, scraping, hitting, or interference with wound healing
Some report reasons of alleviation of negative emotions, self-punishment, seeking attention, or escaping a situation or responsibility