Psych Drugs

Question 1

What are the lab values that indicate increased alcohol use?

Answer 1

Increased: GGT, AST>ALT 2:1

Question 2

What drug is used to tread Alcohol withdrawals?

Answer 2

benzodiazepines

Question 3

What two drugs can be fatal in a withdrawal state?

Answer 3

alcohol and benzo’s

Question 4

Opioid overdose symptoms?

Answer 4

CNS depression, constricted pupils, seizures

Question 5

Opioid withdrawal symptoms?

Answer 5

dilated pupils, sweating, piloerection (goose bumps), diarrhea.

Question 6

Opioid overdose treatment?

Answer 6

naloxone, naltrexone

Question 7

Opioid withdrawal treatment?

Answer 7

methodone, buprenorphine

Question 8

Advantage of benzo’s over barbiturates?

Answer 8

wider safety margin.

Question 9

Benzodiazepine overdose treatment?

Answer 9

flumazenil (competitive benzo antagonist)

Question 10

Benzo’s are used to treat what?

Answer 10

alcohol withdrawal, cocaine overdose, PCP

Question 11

PCP use symptoms?

Answer 11

Rotary nystagmus, psychosis, delirium, seizures.

Question 12

Marijuana use symptoms?

Answer 12

euphoria, anxiety, paranoid delusions, slowed time, increased appetite, dry mouth, conjunctival injection.

Question 13

Heroine addiction is treated with what drugs?

Answer 13

Methadone or Naloxone + Buprenorphine

Question 14

Treatment for alcoholism?

Answer 14

Dilsulfiram, supportive care, AA.

Question 15

Wernicke-Korsakoff syndrome is caused by?

Answer 15

Thiamine (vitamine B1) deficiency.

Question 16

Wernicke-Korsakoff triad?

Answer 16

confusion, opthalmoplegia, ataxia

Question 17

Wernicke-Korsakoff treatment?

Answer 17

Thiamine (vit B1)

Question 18

Delirium tremens (alcohol withdrawal) is treated with?

Answer 18

Benzodiazepines

Question 19

ADHD med?

Answer 19

Methylphenidate

Question 20

Typical antipsychotics meds?

Answer 20

(TFH) Trifluoperazine, Fluphenazine, Haloperidol

Question 21

Typical antipsychotics meds side effects?

Answer 21

High dose (T.H.F)=  EPS, Low dose (C.T) = corneal & retinal deposits.
EPS:  4 hours: dystonia, 4 days: akathisia, 4 weeks bradykinesia, 4 months: tardive dyskinesia

Lowering dopamine levels = increased prolactin = galactorrhea

NMS: “FEVER” Fever, Encepalopathy, Vitals unstable, Elevated enzymes, Rigidity of muscles

Question 22

Atypical Antipsychotic meds?

Answer 22

Olanzapine, clozapine, quetipine, risperidone, aziprasole, ziprasidone

Question 23

Atypical Antipsychotic meds side effects?

Answer 23

Olanzapine & Clozapine = weight gain
Clozapine: agranulocytosis (monitor WBC levels)
Ziprasidone: prolonged QT

Question 24

Atypical Antipsychotic uses?

Answer 24

schizophrenia, bipolar, OCD, anxiety, depression, mania, tourette’s

Question 25

Lithium used for?

Answer 25

Bipolar

Question 26

Lithium side effects?

Answer 26

``` "LMNOP": Lithium side effects: Myoclonus (twitches) Nephrogenic diabetes insipidus hypOthyroidism Pregnancy problems ```

Question 27

Buspirone used for?

Answer 27

Anxiety. | does not cause sedation, won't interact with alcohol

Question 28

SSRI's?

Answer 28

``` (Flashbacks Paralyze Senior Citizens) Fluoxetine Paroxitine Sertraline Citolapram ```

Question 29

SSRI mechanism of action?

Answer 29

Increases serotonin (5-HT1a) by blocking re-uptake in the synapse.

Question 30

SSRI side effects?

Answer 30

Serotonin syndrome: "SMARTS" - Sexual dysfunction, Sweating - myoclonus - ANS instability - Rigidity - Temperature icrease - Seizure

Question 31

SSRI are used to treat what conditions?

Answer 31

``` SAD-BOPP: Social phobia Anxiety Depression Bulemia OCD PTSD Panic attacks ```

Question 32

What do you treat Serotonin syndrome with?

Answer 32

Cyproheptadine

Question 33

SNRI's?

Answer 33

"DV" Duloxitine Venlafaxine

Question 34

SNRI's uses?

Answer 34

Duloxitine: diabetic neuropathy Venlafaxine: generalized anxiety, panic disorder

Question 35

SNRI's side effects?

Answer 35

increased BP is most common

Question 36

TCA's?

Answer 36

"iptyline", "ipramine", amoxipine, doxipine

Question 37

TCA uses?

Answer 37

Major depression Bed wetting (imipramine) OCD (clomipramine) fibromyalgia

Question 38

TCA side effects?

Answer 38

3 C's: Convulsions, Coma, Cardiotoxicity - a1 blocking effects (hypotension) - anticholinergic effects: tachycardia, urinary retention, dry mouth

Question 39

TCA cardiotoxicity is treated with what?

Answer 39

NaHCO3 (sodium bicarb)

Question 40

MAO's?

Answer 40

"MAO Takes Pride In Shanghi" - Tranylcypromine - Phenelzine - Isocarboxazid - Selegeline

Question 41

MAO uses?

Answer 41

Atypical depression, anxiety, hypochondriasis

Question 42

MAO toxicity / side effects?

Answer 42

``` Hypertensive crisis due to Tyramine (from wine & cheese) CNS stimulation (don't give with other stimulants) ```

Question 43

Bupropion used for?

Answer 43

smoking cessation and increases dopamine and Nor-Epi

Question 44

Trazadone moa?

Answer 44

blocks serotonin reuptake.

Question 45

Trazadone side effect?

Answer 45

sedation, priapism "trazabone!"

Question 46

Fomepizole used for?

Answer 46

treat methanol, ethylene glycol poisoning. | competitive inhibitor with alcohol dehydrogenase