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Psych Drugs Flashcards

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1
Q

What are the lab values that indicate increased alcohol use?

A

Increased: GGT, AST>ALT 2:1

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2
Q

What drug is used to tread Alcohol withdrawals?

A

benzodiazepines

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3
Q

What two drugs can be fatal in a withdrawal state?

A

alcohol and benzo’s

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4
Q

Opioid overdose symptoms?

A

CNS depression, constricted pupils, seizures

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5
Q

Opioid withdrawal symptoms?

A

dilated pupils, sweating, piloerection (goose bumps), diarrhea.

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6
Q

Opioid overdose treatment?

A

naloxone, naltrexone

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7
Q

Opioid withdrawal treatment?

A

methodone, buprenorphine

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8
Q

Advantage of benzo’s over barbiturates?

A

wider safety margin.

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9
Q

Benzodiazepine overdose treatment?

A

flumazenil (competitive benzo antagonist)

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10
Q

Benzo’s are used to treat what?

A

alcohol withdrawal, cocaine overdose, PCP

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11
Q

PCP use symptoms?

A

Rotary nystagmus, psychosis, delirium, seizures.

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12
Q

Marijuana use symptoms?

A

euphoria, anxiety, paranoid delusions, slowed time, increased appetite, dry mouth, conjunctival injection.

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13
Q

Heroine addiction is treated with what drugs?

A

Methadone or Naloxone + Buprenorphine

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14
Q

Treatment for alcoholism?

A

Dilsulfiram, supportive care, AA.

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15
Q

Wernicke-Korsakoff syndrome is caused by?

A

Thiamine (vitamine B1) deficiency.

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16
Q

Wernicke-Korsakoff triad?

A

confusion, opthalmoplegia, ataxia

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17
Q

Wernicke-Korsakoff treatment?

A

Thiamine (vit B1)

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18
Q

Delirium tremens (alcohol withdrawal) is treated with?

A

Benzodiazepines

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19
Q

ADHD med?

A

Methylphenidate

20
Q

Typical antipsychotics meds?

A

(TFH) Trifluoperazine, Fluphenazine, Haloperidol

21
Q

Typical antipsychotics meds side effects?

A 
High dose (T.H.F)=  EPS, Low dose (C.T) = corneal & retinal deposits.
EPS:  4 hours: dystonia, 4 days: akathisia, 4 weeks bradykinesia, 4 months: tardive dyskinesia

Lowering dopamine levels = increased prolactin = galactorrhea

NMS: “FEVER” Fever, Encepalopathy, Vitals unstable, Elevated enzymes, Rigidity of muscles

22
Q

Atypical Antipsychotic meds?

A

Olanzapine, clozapine, quetipine, risperidone, aziprasole, ziprasidone

23
Q

Atypical Antipsychotic meds side effects?

A

Olanzapine & Clozapine = weight gain
Clozapine: agranulocytosis (monitor WBC levels)
Ziprasidone: prolonged QT

24
Q

Atypical Antipsychotic uses?

A

schizophrenia, bipolar, OCD, anxiety, depression, mania, tourette’s

25
Q

Lithium used for?

A

Bipolar

26
Q

Lithium side effects?

A 
"LMNOP":  
Lithium side effects: 
Myoclonus (twitches)
Nephrogenic diabetes insipidus
hypOthyroidism
Pregnancy problems
27
Q

Buspirone used for?

A

Anxiety.

does not cause sedation, won’t interact with alcohol

28
Q

SSRI’s?

A 
(Flashbacks Paralyze Senior Citizens)
Fluoxetine
Paroxitine
Sertraline
Citolapram
29
Q

SSRI mechanism of action?

A

Increases serotonin (5-HT1a) by blocking re-uptake in the synapse.

30
Q

SSRI side effects?

A

Serotonin syndrome: “SMARTS”

  • Sexual dysfunction, Sweating
  • myoclonus
  • ANS instability
  • Rigidity
  • Temperature icrease
  • Seizure
31
Q

SSRI are used to treat what conditions?

A 
SAD-BOPP:
Social phobia
Anxiety
Depression
Bulemia
OCD
PTSD
Panic attacks
32
Q

What do you treat Serotonin syndrome with?

A

Cyproheptadine

33
Q

SNRI’s?

A

“DV”
Duloxitine
Venlafaxine

34
Q

SNRI’s uses?

A

Duloxitine: diabetic neuropathy
Venlafaxine: generalized anxiety, panic disorder

35
Q

SNRI’s side effects?

A

increased BP is most common

36
Q

TCA’s?

A

“iptyline”, “ipramine”, amoxipine, doxipine

37
Q

TCA uses?

A

Major depression
Bed wetting (imipramine)
OCD (clomipramine)
fibromyalgia

38
Q

TCA side effects?

A

3 C’s: Convulsions, Coma, Cardiotoxicity

  • a1 blocking effects (hypotension)
  • anticholinergic effects: tachycardia, urinary retention, dry mouth
39
Q

TCA cardiotoxicity is treated with what?

A

NaHCO3 (sodium bicarb)

40
Q

MAO’s?

A

“MAO Takes Pride In Shanghi”

  • Tranylcypromine
  • Phenelzine
  • Isocarboxazid
  • Selegeline
41
Q

MAO uses?

A

Atypical depression, anxiety, hypochondriasis

42
Q

MAO toxicity / side effects?

A 
Hypertensive crisis due to Tyramine (from wine & cheese)
CNS stimulation (don't give with other stimulants)
43
Q

Bupropion used for?

A

smoking cessation and increases dopamine and Nor-Epi

44
Q

Trazadone moa?

A

blocks serotonin reuptake.

45
Q

Trazadone side effect?

A

sedation, priapism “trazabone!”

46
Q

Fomepizole used for?

A

treat methanol, ethylene glycol poisoning.

competitive inhibitor with alcohol dehydrogenase

SHELF: Psych Drugs (1 decks)

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