PSYCH COMMONLY USED MEDS Flashcards

1
Q

Citalopram - Brand Name

A
  • Celexa
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2
Q

Citalopram - Class

A
  • SSRI
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3
Q

Citalopram - Dosing

A
  • 20 - 40 mg/day
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4
Q

Citalopram - Commonly Prescribed For

A
  • MDD (FDA) approved
  • PMDD
  • OCD
  • GAD
  • PTSD
  • Social anxiety disorder/social phobia
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5
Q

Citalopram - Augmenting Combos for Treatment Resistance or Partial Response

A
  • Trazodone (insomnia)
  • Bupropion (sexual dysfunction, emotional flattening)
  • Mirtazapine (insomnia, agitation, GI)
  • Modafinil (fatigue, sleepiness)
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6
Q

Citalopram - Side Effects

A
  • Sedation (mild antihistamine properties)
  • Sexual dysfunction
  • Dose shouldn’t exceed 20 mg/day in > 60 y/o
  • Increased bleeding risk with anticoagulants/NSAIDs
  • Activation
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7
Q

Citalopram - Half-Life

A
  • 23 - 45 hours
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8
Q

Escitalopram - Brand Name

A
  • Lexapro
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9
Q

Escitalopram - Class

A
  • SSRI
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10
Q

Escitalopram - Dosing

A
  • 10 - 20 mg/day
  • Some patients can be dosed at 30-40
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11
Q

Escitalopram - Commonly Prescribed For

A
  • MDD (FDA Approved)
  • GAD (FDA Approved)
  • Panic disorder
  • OCD
  • PTSD
  • PMDD
  • Social anxiety (social phobia)
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12
Q

Escitalopram - Augmenting Combos for Treatment Resistance or Partial Response

A
  • Trazodone (insomnia)
  • Bupropion (sexual dysfunction, emotional flattening)
  • Mirtazapine (insomnia, agitation, GI)
  • Modafinil (fatigue, sleepiness)
  • Gabapentin (anxiety - if all else fails)
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13
Q

Escitalopram - Side Effects

A
  • Sexual dysfunction
  • GI
  • Sweating
  • Activation
  • Increased bleeding risk with anticoagulants/NSAIDs
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14
Q

Escitalopram - Half-Life

A
  • 27 - 23 hours
  • Steady state plasma concentrations achieved within 1 week
  • Food doesn’t affect absorption
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15
Q

Fluoxetine - Brand Name

A
  • Prozac
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16
Q

Fluoxetine - Class

A
  • SSRI
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17
Q

Fluoxetine - Dosing

A
  • 20 - 80 mg/day
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18
Q

Fluoxetine - Commonly Prescribed For

A
  • MDD (FDA Approved)
  • OCD (FDA Approved)
  • Panic Disorder (FDA Approved)
  • PMDD (FDA Approved)
  • Bulimia (FDA Approved)
  • Bipolar depression/treatment-resistant depression (with zyprexa) (FDA Approved)
  • Social anxiety disorder
  • PTSD
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19
Q

Fluoxetine - Augmenting Combos for Treatment Resistance or Partial Response

A

-

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20
Q

Fluoxetine - Side Effects

A
  • Sexual dysfunction
  • GI disturbance
  • CNS (insomnia, sedation, agitation, H/A, dizziness)
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21
Q

Fluoxetine - Half-Life

A

-

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22
Q

Fluvoxamine - Brand Name

A
  • Luvox
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23
Q

Fluvoxamine - Class

A
  • SSRI
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24
Q

Fluvoxamine - Dosing

A
  • 100 - 200 mg/day
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25
Fluvoxamine - Commonly Prescribed For
- OCD (FDA Approved) - Social anxiety/phobia (FDA Approved) - Depression - Panic disorder - GAD - PTSD
26
Fluvoxamine - Augmenting Combos for Treatment Resistance or Partial Response
-
27
Fluvoxamine - Side Effects
- Bradycardia w/ coadministration of diltiazem -Propranolol/metoprolol: reduce dose if administered/titrate cautiously - Smokers 25% increase in metabolism - Sexual dysfunction - GI disturbance - CNS (insomnia, sedation, agitation, H/A, dizziness)
28
Fluvoxamine - Half-Life
-
29
Paroxetine - Brand Name
- Paxil
30
Paroxetine - Class
- SSRI
31
Paroxetine - Dosing
- 20 - 50 mg/day
32
Paroxetine - Commonly Prescribed For
- MDD (FDA Approved) - OCD (FDA Approved) - Panic disorder (FDA Approved) - PTSD (FDA Approved) - Social anxiety/social phobia (FDA Approved) - GAD (FDA Approved) - PMDD (FDA Approved) - Weight gain (FDA Approved) - Vasomotor symptoms (FDA Approved)
33
Paroxetine - Augmenting Combos for Treatment Resistance or Partial Response
- Best used for complicated PTSD and needing sleep
34
Paroxetine - Side Effects
- Anticholinergic side effects (constipation, dry mouth) - Dizziness - Sexual dysfunction - GI disturbance - CNS
35
Paroxetine - Half Life
-
36
Sertraline - Brand Name
- Zoloft
37
Sertraline - Class
- SSRI
38
Sertraline - Dosing
- 50 - 200 mg/day
39
Sertraline - Commonly Prescribed For
- MDD (FDA Approved) - PMDD (FDA Approved) - OCD (FDA Approved) - PTSD (FDA Approved) - Panic disorder (FDA Approved) - Social anxiety/social phobia (FDA Approved) - GAD
40
Sertraline - Augmenting Combos for Treatment Resistance or Partial Response
- Highest preferred SSRI - 1st line for pregnant/breastfeeding mothers - 1st line for pt w/ hx of MI/CVA
41
Sertraline - Side Effects
- Sexual dysfunction - GI disturbance - CNS (insomnia, sedation, agitation, H/A, dizziness)
42
Sertraline - Half-Life
-
43
Duloxetine - Brand Name
- Cymbalta
44
Duloxetine - Class
- SNRI
45
Duloxetine - Dosing
- 40 - 120 mg/day - No evidence of benefit after > 60 mg/day
46
Duloxetine - Commonly Prescribed For
- MDD (FDA Approved) - DPNP (FDA Approved) - Fibromyalgia (FDA Approved) - GAD (FDA Approved) - Chronic musculoskeletal pain (FDA Approved) - OCD - Stress/urinary incontinence - Neuropathic/chronic pain
47
Duloxetine - Augmenting Combos for Treatment Resistance or Partial Response
- California rocket fuel = SNRI + mirtazapine
48
Duloxetine - Contraindications
- Hepatic failure/liver dysfunction/alcohol use disorder - Uncontrolled narrow-angle glaucoma - Increase in risk of bleeding events (NSAIDs, aspirin)
49
Duloxetine - Side Effects
- Orthostatic hypotension - Dose-dependent increase in BP - Sexual SE - GI disturbance - CNS effects
49
50
Venlafaxine - Brand Name
- Effexor
51
Venlafaxine - Class
- SNRI
52
Venlafaxine - Dosing
- 75 - 225 mg/day
53
Venlafaxine - Commonly Prescribed For
- MDD (FDA Approved) - GAD (FDA Approved) - Social anxiety/phobia (FDA Approved) - Panic disorder (FDA Approved) - PTSD - PMDD
54
Venlafaxine - Augmenting Combos for Treatment Resistance or Partial Response
- California rocket fuel = SNRI + mirtazapine
55
Venlafaxine - Side Effects
- HTN (monitor BP) - Sweaty - Sexual SE - GI disturbance - CNS effects
56
Mirtazapine - Brand Name
- Remeron
57
Mirtazapine - Class
- Alpha 2 antagonist
58
Mirtazapine - Dosing
- 15 - 45 mg/night
59
Mirtazapine - Commonly Prescribed For
- MDD (FDA Approved) - Panic disorder - GAD - PTSD
60
Mirtazapine - Augmenting Combos for Treatment Resistance or Partial Response
- Good for sleep and appetite stimulation - Higher doses = norepi stimulation
61
Mirtazapine - Side Effects
-