Psych Case File and U world Flashcards
This neurotransmitter is most often altered in OCD
Serotonin
This type of medication is the first line treatment of OCD
SSRI
Clomipramine, fluvoxamine, fluoxetine, paroxetine, sertraline
What two conditions commonly occur with touretts?
OCD and ADHD
Drug to give to a depressed smoker?
Buproprion
What is the only antipsychotic that has been shown to be effective in treatment resistent schizophrenia especially in cases associated with suicidality?
Clozapine
First line drug class for depression?
What is the next step when the first line does not work?
SSRI (Citalopram, Sertraline, fluoxetine, paroxatine)
When SSRI does not work then the next step would be to try a drug of the same class (e.g. sertraline not working switch to citalopram)
Patient newly on haloperidol has torticolis. Tx?
Benztropine or diphenhydramine
Buproprion should never be used in a patient with a hisotry of this…
Seizures
Signs common in patients with anorexia nervosa
- Osteoporosis
- Euthyroid sick syndrome
- Hyponatremia (water excess)
- Cardiac arrythmia
Anxiety medication that if discontinued abruptly can cause seizures
Alprazolam (xanax)
Fever, rigidity, AMS and automic instability…
NMS
Which drugs cause NMS?
typical antipsychotics like haloperidol
Dopamine blockade
Atypical antipsychotic that most commonly causes tardive dyskinesia?
Resperidone
Good initial medical treatment for a patient with performance anxiety disorder…
Propanolol or Benzo
Choose B blocker if Pt uses drugs
Brain imaging findings consistent with the following disorders:
OCD
Panic disorder
PTSD
Schizophrenia
Autism
OCD: Orbitofrontal and striatum changes
Panic disorder: small amygdala
PTSD: Hippocampal changes
Schizophrenia: Lateral ventricular enlargement
Autism: overal brain enlargement
Clozapine causes this important reaction…
Agranulocytosis
Why imipramine (TCA) is good for bed wetting…
Highly anticholinergic
TCA that is good for OCD
Clomipramine
This drug can cause HTN crisis when combined with aged food due to ______ in the food.
MAOi’s
Tyramine
Antidepressant that causes weight loss. Good for smokers.
Buproprion
This drug causes sedation and weight gain
Mirtazepine (remeron)
Side effects of lithium
Tremor
Polyuria (diabetes insipidus)
Cardiac arrythmia
hypothyroidism
weight gain
edema
leukocytosis
First generation antipsychotics work by…
They treat the (positive or negative) sx of schizophrenia?
Blocking central dopamine receptors
Tx +symptoms of schizophrenia
Most common side effect assocaited with Haldol use…
EPS
These are examples of this drug class….
Risperidone
Olanzepine (zyprexa)
Clozapine
Quetiapine (seroquel)
Ziprazadone (geodon)
Aripiprazole (abilify)
Atypical antipsychotics
Serotonin-dopamine antagonist
Class of meds used to treat akathisia (restlessness) from psychotropic meds
amantidine and levodopa
Antidote to beonzodiazepine overdose
Flumazenil
This is a common treatment for excesive daytime sleepyness…
Modafanil
Clozapine and olanzapine (atypical antipsychotics) have been assiciated with this medical condition…
Metabolic syndrome
Treatment of panic disorder
SSRI with Behavioral cognitive therapy
Short course of benzo–then dicontinue
Side effects of olanzapine
Sedation and weight gain
Treatment for Bipolar I (manic episode with psychotic features)
Valproic acid or lithium
and
atypical antipsychotic
Only drug FDA approved for tx of bipolar in children 12 and older?
Lithium
Best drug for treatment of bipolar in children 12 and under
valproic acid
Bipolar II disorder
Hypomania with episode of depression
Olanzapine and clozapine are both associated with this side effect…
Weight gain and dyslipidemia
When asked about tx for ADHD and methylphenidate or dextromethorphine is not a choice, what is the correct answer? Why?
Amantadine
It has a milder side effect profile
What is the best choice of treatment in a patient who is depressed and also has neuropathy
duloxetine (cymbalta)
Best antidepressant for a pt with depression and does not want to have excessive weight gain or sexual dysfunction
Buproprion (wellbutrin)
Atypical depressive symptoms
weight gain
increased sleep
increased appetite
Medical treatment of serotonin syndrome
cyproheptadine
This atypical antipsychotic has a side effect of QT prolongation
Ziprasidone (Geodon)
Which of the antipsychotics is least likely to cause metabolic issues (good for DM and fat ppl)
Arapiprazole (abilify)
Ziprasidone (Geodon)
First line treatment for PTSD
Sertraline and paroxetine
Absolute contraindication to buproprion use?
Seizure condition or predisoposing electrlyte abnormality
