Psych - Autism + Personilty disorders Flashcards

1
Q

How would you define Autism?

A

It is a lifelong (chronic), developmental disability that affects how a person communicates with and releates to other people + the world around them

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2
Q

Autism disorder is a social disabiity - what is the triad of autism in regard to this social disability?

A
  1. Social communication
    • late to start talking or remain non-verabal
    • difficulty initiating or sustaining convo
    • unusual / repetitve language
    • not responding to name
    • difficulty understanding non-verbal comms
  2. Social interaction
    • difficulty recognising emotion in self + others
    • ↓ eye contact
    • unaware of appropriate social behaviour (share toys, take turns talking)
  3. Social imagination: rigidity of thought, behaviour and play
    • limited range of interests
    • favour one specific toy (heavily)
    • repetitive patterns of play / gestures
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3
Q

Autism is associated with ↑ occurence of several mental health conditions - name some.

A
  1. Anxiety
  2. Depression / low mood (may be worse in adolescence)
  3. OCD (up to 30% of persons with autism)
  4. Sleep disturbance
  5. Gender dysmorphia
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4
Q

What are some known risk factors for autism?

A
  • Males (~4x more likely)
  • 1st degree relatives with ASD (high heritability)
  • ↑ parental age (father > 50 and mother > 40)
  • Exposure to specific chemicals / medications or infections during pregnancy
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5
Q

Review other side of card for Autism history taking / questions.

A

Language + communication:

  • Can they hold a convo?
  • Voice: pitch? monotone? content of speech?
  • Gestures when communicating?
  • Meaningless repitition of speech?

Social + emotional interaction:

  • Making + keeping friends?
  • Understand emotions of others + themselves?
  • How is their eye contact?
  • Ignoring social cues / behaviour appropriate for age?
  • Narrowed interests? Unable to talk about other topics?

Flexiblity / rigidity of thought?

  • Repetitive play?
  • How do they cope with change?
  • Any obsessions? Routines? Rituals?

Behaviour:

  • Temper? Meltdowns?
  • Obsessions, fears, phobias?

Sensory features:

  • Problems with loud noises? textures? water?
  • Sensory seeking? Sensory avoiding?

Birth History:

  • Antenantal - Hx of alcohol, drugs, smoking, illness?
  • Perinatal - delivery problems, ↓ birth weight?
  • Postnatal issues

Developmental Hx:

  • Motor development progressing?
  • Hearing, speech and language progression? - speech regression = RED FLAG
  • Development of social interaction and play?

Family Hx:

  • Learning disabilities?
  • Epilepsy / fits?
  • Alcohol / drug abuse?
  • Domestic violence or care leavers?
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6
Q

What tools can be used to screen for autism spectrum disorder (ASD)?

A
  1. CAST (childhood autism spectrum test)
    • screen children 4-11yrs
    • 39 yes/no questions
  2. ADOS-2 (autism diagnostic observation schedule)
    • for diagnosing and assessing autism
    • series of tasks involving interaction between examiner + testee
    • observations of behaviour converted into quantitative score
  3. ADI-R (autism diagnostic interview-revised):
    • structured interview with parents of individual (about the patient)
    • examines; language / communication, social interaction, restricted, repetitive behaviours and interests
    • min mental age of 24 months (2yrs)
  4. DISCO (diagnostic interview for social and communication disorders):
    • semi-structured interview with parent/care giver
    • 300 questions
    • children + adults of any age
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7
Q

What medical conditions is ASD associated with?

(progress test info)

A
  1. Fragile X syndrome - trinucleotide repeat disorder
    • male (females far less affected)
    • autism is more common
    • learning difficulties
    • large low set ears, long thin face, high arched palate
    • macroorchidism (large testes)
    • hypotonia
    • mitral valve prolapse
  2. Rett’s syndrome - non genetic, new mutation MECP2 gene
    • female (males die after birth)
    • autism like features: language, repetitive movements
    • slower growth
    • walking impairment
    • smaller head size
    • Complications: seizures, scoliosis, sleep disorders
  3. Congential rubella (especially exposure during 1st trimester)
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8
Q

Is ADHD more common on males or females?

A

Males

(~4x more than females)

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9
Q

What are the 2 categories of features associated with ADHD?

A

1) Inattention and/or
2) Hyperactivity / Impulsivity

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10
Q

What features fall into the diagnostic categores 1) inattention 2) hyperactivity/impuslivity for ADHD?

A

Inattention:

  • Doens’t follow through on instructions
  • Reluctant to engage in mentally-intense tasks
  • Distracted
  • Can’t sustain tasks
  • Poor organisation of tasks/activities
  • Forgets daily activities
  • Often loses things necessary for tasks/activities
  • Doesn’t listen when spoken to

Hyperactivity / impulsivity:

  • Unable to play quietly
  • Talks excessively
  • Doesn’t wait turn
  • Spontaneously leave seat when expected to sit
  • Often ‘on the go’
  • Interruptive or intrusive to others
  • Answer prematurely, before a question has been finished
  • Run and climb in situations where it is not appropriate
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11
Q

What are the diagnostic criteria for ADHD?

A
  1. Features from inattention and/or hyperactivity/impulsivity lists:
    1. If < 16yrs then 6 features
    2. If > 17yrs then 5 features
  2. Symptoms cause significant functional impairment; socially, psychologically, educationally etc.
  3. Pervasive - symptoms occur in 2 or more settings; social, home, school etc.
  4. Onset < 7 yrs (DSM-V) < 6 yrs (ICD-10)
  5. Persists for > 6/12 months
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12
Q

How is ADHD managed?

A

Conservative:

  1. Education on ADHD impact
  2. Parenting strategies - involvement from both parents
  3. Liason for school, college, uni
  4. Behaviour management strategies

Pharmacological: - stimulants!!

  1. 5+ and young people
    • 1st line = methylphenidate
      • Low starting dose
      • Titrate dose against behaviour + school work
    • 2nd line = lisdexamfetamine
      • If 6-week trial of methylphenidate at therapeutic dose did’t work
    • Consider dexamfetamine IF responding to lisdexamfetamine but don’t tolerate long effect profile
  2. Adults:
    • 1st line = methylphenidate or lisdexamfetamine
      • Try the other if the 1st didn’t work
    • Consider dexamfetamine IF responding to lisdexamfetamine but don’t tolerate long effect profile
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13
Q

How is autism managed?

A

Conservative:

  • Psychotherapy - both parents + patients:
    • CBT
    • Behaviour management programmes
    • Applied behavioural analysis program - intense program (40hr a week for 3yrs) based on operant conditioning, imitation and reinforcement
  • Social - led by functional assessment:
    • Carers
    • Respite care
    • Education of peers in school
    • Learning support / special schools

Pharmacological:

  • 2nd gen anti-psychotics = 1st line for children + adolescents with ASD
    • Risperidone (only one liscenced in UK) - for aggressive, challenging behaviour in autistic children
  • SSRIs - low dose, used for restricted repetitive behaviours (evidence limited)
  • Melatonin - ↓ sleep latency (time taken to fall alseep)
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14
Q

What is ‘Conduct Disorder’?

A
  • Define:
    • A repetitive and persistent pattern of behaviour in which either the basic rights of others or major age appropriate societal norms or rules are violated
    • Lasting > 6/12
  • Can occur in infancy, childhood or adolescence
  • Features:
    • aggressive / cruel behaviour; towards other people or animals
    • frequent + severe temper tantrums for age
    • deceitfulness / lies frequently
    • thievery / breaking + entering
    • frequent physical fights
    • carrying / use of a weapon
    • destruction of property
    • violation of rules that is persistent and repetitive
    • bullying
  • Risks:
    • risk of developing mental disorder
    • retaliation from others due to behaviour
    • substance misuse
    • risk of harm to others (aggressive behaviour)
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15
Q

What would the management plan for a conduct disorder involve?

A
  1. Multisystemic therapy (MST)
    • Identify problematic behaviours
    • Interventions for each behaviour (tackle one at a time) and how to monitor progress
  2. Work on any substance misue
  3. Continued assessment of mental state to monitor for development of mental health disorder
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16
Q

What one of the following is not a common comorbidity in young people with conduct disorder?

  • ADHD
  • Psychosis
  • Learnign difficulties
  • Depression
  • Austism spectrum disorder
A

Psychosis

  • 46% of boys / 36% of girls who have conduct disorder, have at least 1 coexisting mental health problem:
    • ADHD (>40%)
    • Learning difficulties
    • Autistic Spectrum Disorder
    • Depression
    • Anxiety
17
Q

Which one of the following is recommended first line for the treatment of conduct disorder?

  • Interpersonal therapy
  • Psychodynamic psychotherapy
  • Multi systemic therapy
  • Fluoxetine
  • Diazepam
A

Multi systemic therapy

  • Treatment of conduct disorder is:
    • Multi-modal, Family-based and social systems-based approach
  • Social and cognitive problem solving programmes
  • Pharmacologial interventions only to treat co-morbidites e.g. anti-depressant for depression
18
Q

Which of the following risk factors are not associated with conduct disorder?

  • Substance misuse
  • ADHD
  • Physical or sexual abuse
  • Parental family history
  • Low IQ
  • Being female
A

Being female (male is a risk factor)

Risk factors:

  • Male
  • Substance misuse
  • ADHD
  • Physical or sexual abuse
  • Parental family history
  • Low IQ
19
Q

Which of the following would point towards a diagnosis of Oppositional Defiant Disorder instead of Conduct Disorder?

  1. Negative and oppositional behaviour present at home with well known adults or peers, but not at school
  2. Negative and oppositional behaviour in all areas of life, both at school and home
  3. A 16 year old who severely bullies primary school children
  4. Extreme levels of aggressive behaviour that is pervasive, across all areas of life.
  5. Aggressive behaviour that goes beyond mere defience, disobedience or disruptiveness
A

1) Negative and oppositional behaviour present at home with well known adults or peers, but not at school

Oppositional definat disorder (ODD) is defined as:

  • Definition:
    • at least 6 months of negative, hostile, disobedient and defiant behaviour, WITHOUT serious violations of societal norms or the rights of others
  • Symptoms:
    • demonstrated by age 8, no later than adolescence (onset earlier than conduct disorder)
    • are present at home with those the pt knows very well
    • often not present at school or with other adults / peers
20
Q

Emotionally unstable personality disorder (EUPD) is split into 2 types,

what are they?

A
  1. Impulsive type EUPD
  2. Borderline type EUPD

Borderline personality disorder and EUPD are synonamous, only the ICD-10 splits it into 2 types, in the DSM-5 they are the same

21
Q

What are some features of EUPD?

A
  • Affective instability - repeated, rapid and abrupt shifts in mood e.g. confidence to despair (can be similar to bipolar)
  • Chronic feelings of emptiness
  • Unstable interpersonal relationships which alternate between idealization and devaluation
  • Impulsivity in potentially self damaging area (e.g. Spending, sex, substance abuse)
  • Recurrent suicidal behaviour
  • Fear of abandonment / rejection - tries to avoid real or imagined abandonment
  • Unstable self image
  • Difficulty controlling temper
  • Quasi psychotic thoughts - e.g. pseudohallucinations (voice lacking quality of true auditory hallucination)

Note: borderline personality disorder almost always presents with comorbidities; depression, anxiety, easting disorders, PTSD, substance misuse and bipolar disorder. It can also overlap with psychosis, but the delusions / hallucinations are often brief and linked to periods of extreme emotional instability.

22
Q

What is a personality disorder?

A

A personality disorder are traits that deviate from expectations of the culture of the individual

Traits will be:

  • long lasting (not episodic)
  • inflexible
  • pervasive - affect many personal / social situations
  • impact behaviour and thoughts
  • appear in childhood / adolescence
23
Q

What causes personality disorders?

A

Nature + Nurture

  • Genetic predisposition
  • Parents often have development disturbances thus children are exposed to:
    • substance misuse
    • erratic parenting
    • marital discord
    • abuse
  • Brain injuries of frontal lobe
  • Cognitive dysfunction e.g. dementia of frontal lobe
24
Q

How are personality disorders managed?

A

Bio/Psycho/Social

  • Biological:
    • Treat any co-morbidity
  • Psychological:
    • Dialectical behavior therapy (DBT)
    • Balint groups - group of clinicians who meet + discuss cases to improve clinician-patient relationship
  • Social:
    • Support
    • Structure
    • Crisis management
25
Q

What is dialectical behaviour therapy (DBT)?

A

DBT:

Main goals = build a life you feel is worth living

  • DBT involves the setting of goals and aiding the client in reaching those goals (some goals are put before others e.g. keeping client alive and continuing to come to therapy)
  • Found to be useful for:
    • EUPD
    • Mood disorders
    • Suicidal ideation
    • Change of behaviours e.g. self-harm or substance abuse