Psych Flashcards

1
Q

Which areas of the brain are associated with depression

A

Subcallosal cingulate Cortex (area 25)
Right anterior insula
Anterior cingulate gyrus
Hippocampus, amygdala, hypothalamus

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2
Q

DSM 5 Criteria for depression

A
Five or more for at least 2 weeks:
Sleep disturbance
Anhedonia
Depressed mood
Fatigue
Appetite/weight change
Concentration
Exercise - psychomoter agitation/retardation
Suicidality/worthlessness/guilt
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3
Q

SSRI SE

A
Hyponatremia
OP in elderly
Dry mouth, sweatinng
Agitation
Sexual dysfunction
Weight gain
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4
Q

SNRI SE

A

Cardiac toxicity in OD

Increased rate of seizures

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5
Q

Indications for ECT

A
Melancholic depression
Psychotic depression
Catatonia
High suicide risk
Poor oral intake
Poor response to medication
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6
Q

Tx of psychotic depression

A

antipressents and antipsychotics +/- ECT

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7
Q

MOA of antipsychotics

A

All work through D2 receptor blockade or are partial blockers

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8
Q

Most effective antipsychotic

A

Clozapine

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9
Q

Antipsychotic causing the least EPS

A
  1. Clozapine
  2. Quetiapine
  3. Olanzapine
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10
Q

Antipsychotic causing the most EPS

A

Haloperidol

Chlorpromazine

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11
Q

Antipsychotics causing the least hyperprolactinemia

A

Aripirazole
Clozapine
Quetiapine

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12
Q

Antipsychotics causing the most hyperprolactinemia

A

Paliperidone
Risperidone
Haloperidol
Amisulpride

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13
Q

Antipsychotics causing the most sedation

A

Clozapine
Chlorpromazine
Quetiapine

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14
Q

Antipsychotics causing the most weight gain

A

Clozapine

Olanzapine

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15
Q

Antipsychotics causing the least weight gain

A

Haloperidol
Lurasidone
Ziprasidone

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16
Q

SE of clozapine

A
Agranulocytosis
myocarditis
Cardiomyopathy
Convulsions
Serious weight gain
Diabetes
SEdation
Anticholinergic effects
Tachycardia
17
Q

Somatoform Symptom Disorder

A

Defined mainly by the presence of physical symptoms as the predominant feature.

18
Q

Illness anxiety disorder

A

A. Preoccupation with having or acquiring a serious illness.
B. Somatic symptoms are not present or if present, are only mild in intensity
C. performs excessive health-related behaviours
D. Present for at least 6 months

19
Q

Postictal psychosis

A

o Usually follow exacerbations, especially clusters, of complex partial seizures
o Characteristically, cessation of seizure activity is followed by a brief interlude – a ‘lucid interval’ – of 12 to 72 hours before the mental states deteriorates

20
Q

Interictal psychosis

A

o Does resemble schizophrenia in its phenomenological manifestations, pursues a similar course, is as responsive to antipsychotic medication and is largely uninfluenced by concurrent seizure activity