Psych Flashcards
Delirium Tremens
ETOH withdrawal
low serum B12
Acute delirium
Mx - Cause, otehrwise haloperidol
Pharm causes of depression
Prednisolone
Frontal lobe injury
Px - Hyperphagia, lability&irritability, hypersexuality, inappropriate affect
Wilson’s
Ax - Cu accumulation
Px - jaundice, KF rings, Psych=aggression, disinhibition
Huntington’s
Ax - chromosome 4p triplet repeat. Cell loss in basal ganglia, sunstantia nigra and verebellum
Px movement disorder, choreiod and athetoid movements dementia, personality changes
Stroke psych complications
Depression
Schizophrenia subtypes
Hebephrenic/disorganized: predominance of thought disorder and affective symptoms. social withdrawal, fatuous affect, negative symptoms develop rapidly
Catatonic: psychomotor disturbances or catatonic behaviour, waxy flexibility, negativism, aversion
Paranoid: delusions and hallucinations
Residual: +ve Sx are replaced by -ve Sx
Simple: insidious development of oddities of conduct, inability to meet demands of society and decline in total performance
Lifetime risk is 0.4% twins 50%
Neuroleptic malignant syndrome
Emergency
Ax - complicaiton of antipsychotics dopamine blockage.
Px - Confused, dec GCS, extra-pyramidal Sx, fever, hypotension, tachycardia
Mx - stop antipsychotic
Aripiprazole
Newer antipsychotic, less SE’s
SE: Nausea, insomnia
Olanzapine
2nd gen antipsychotic
Treating +ve Sx
SE: wt gain and diabteic control
Clozapine
Treatment resistant schizophrenia
SE: Neutropenia or agranulocytosis
Sertraline
SSRI antidepressant
Section 3
Detain for 6 mnths, when the person is known to mental health services
Section 2
Detain for 28 days, initial assessment
Section 135
Warrant permitting police to search premises and remove pts from those premises
Section 4
Detained for 72hrs, emergency, should be converted to section 2. 1 medical recommendation
Section 5(2)
(Dr) Detain for 72hrs on inpts for a full mental health assessment
Lewy body dementia
Second most common after Alzheimer’s
Day to day fluctuation of cognition, visual hallucinations, parkinsonian
Antipsychotics avoided
Normal pressure hydrocephalus
Gait, urinary incontinence, dementia
Hippocampal atrophy on MRI
Alzheimer’s
MOA of drugs targeting cognitive symptoms of dementia
Drugs that Inc ACh i.e. ACh esterase inhibitors
Day to day fluctuating consciousness, visual hallucinations, Parkinsonism
Lewy body dementia
Excessive worry over memory loss in old people.
Depression
Somatization is a common presentation of ……… in old age
Depression
Partition delusions ‘radiation through ceiling’
VLOSP
Body fat in elderly increases/decreases
Fat soluble drugs will have a longer/shorter duration of effect in older people
Increases
Longer
Px - pyrexia, rigidity, tachycardia, raised WCC, raised CK, fluctuating consciousness, younger male pts
Ax - antipsychotics
Mx - stop antipsychotics, IV fluids (bromocriptine/dopamine agonist may be used)
Neuroleptic malignant syndrome
Wake up screaming w/ no recollection the next day
Night terror
Wake up screaming w/ recollection
Nightmares
Suicide RF’s
Male 45 divorced, single, widowed unemployed psych illness prev episode of self harm chronic physical illness adverse life events
Annual rsk of suicide
Annual incidence of self-harm
1 in 10,000
3-1000
Delusional psychosis infected w/ parasites
Ekbom’s
Nihilistic delusion that one is dead, does not exist, is decaying etc
Cotard syndrome
Delusional belief that someone of a higher social status is in love with you
De Clerambault’s
Mimicking ideas of crazy w/ approximate answers showing understanding of underlying Q
Prison inmates before trial
Ganser’s
Delusion that persecutor can change form
Fregoli’s
Delusional jealousy
Othello syndrome
Px - >2years of multiple, variable physical Sx of no underlying cause, refusal to accept Dr’s reassurance, impairment of social function, Sx not intentionally produced,
Somatization disorder
Px - dazed and inability to process external stimuli after exceptional physical or mentally stressful stimuli
Acute stress reaction
Restless legs
Akathisia
Px - Lip smacking, sucking, chewing
Ax - extrapyramidal SE of antipsychotics e.g. haloperidol
Tardive dyskinesia
Atypical antipsychotics (2) MOA
Olanzapine, Clozapine
Block dopamine D1+D4 receptors
Px - severe HTN, tachycardia, pyrexia, hyperreflexia, SSRI + St Johns Wort
Serotonin syndrome
Snapshot low mood
Dysphoria
Snapshot exaggerated high mood
Euphoria
Distorted recall of past experiences
Paramnesia
Inability to recall past experiences
Amnesia