PSYCH Flashcards
alcohol drugs
naltrexone vs acamprosate vs disulfiram
naltrexone is first line to decrease craving and increase abstinence; can be started while still drinking; mu opioid receptor antagonist and decreases alcohol effect
acamprosate is a glutamate modulator; used for maintenence AFTER abstinence is achieved
disulfiram inhibits alcohol dehydrogenase to discourage drinking; must be used in motivated and abstinent people
neuroleptic malignant syndrome
sx?
tx?
fever >104, mental change, muscle rigidity and autonomic instability
stop neuroleptics and give dantrolene or bromocriptine + hydration/cooling
which bug is associated with uti and struvite stones?
proteus
urease producing –> makes ammonium
anorexia vs bulimia
anorexia has significantly low BMI (can have compensatory behavior)
bulimia always has compensatory behavior but maintains normal body weight
both are distorted view of body
how long is adequate trial length before switching to a second SSRI?
6 weeks
contraindication for bupropion use in depression?
history of seizures or bulimia
If autistic patient is aggressive… Treatment with what?
Antipsychotic medication such as risperidone
Tx for Tourette’s
Antipsychotics such as haloperidol or rosperidone
Or clonidine
Treatment for major depression
First line is SSRI like fluoxetine paroxetine sertraline citalopram or escitalopram
After 4 weeks can switch to another ssri
After that, can increase dose or switch to tac
Best medication for patient with depression and neuropathic pain
Duloxetine
Best treatment for depression who is scared of weight gain or sexual side effects OR smoker trying to quit
Bupropion
Bipolar 1 versus 2
1 is mania and depression
2 is hypomanic and depression
Patient in lithium who comes in aggressive and punched nurse…first step
Give antipsychotic
Don’t need to verify lithium level given that his symptoms are so acute
Cyclothymic
Depression and hypomanic episodes on and off for 2 years
Tx w lithium, valproate, or antipsychotic and psychotherapy
Atypical depression sxs
Tx?
Weight gain
Increased sleep
Increased appetite
Tx w MAOIs
Seasonal pattern depression
Fall and winter mood changes
Tx w phototherapy and bupropion or SSRI
MAOIs
PhenelZine
Isocarboxazid
Tranylcypromine
Mirtazipine has risk of
Weight gain and sedation
Lamotrigine has risk of
Steven Johnson syndrome
What is the single most effective treatment for depression?
Electroconvulsive therapy is usually used for suicidal patients unresponsive to regular meds
Brief psychotic disorder versus schizophreniform disorder’s versus schizophrenia
Brief psychotic disorder or is one month or less
Schizophreniform is six months or less
Schizophrenia is more than 6 mo
Side affects of the following:
– Olanzapine – risperidone – quetiapine
-ziprasidone
-clozapine
Olanzapine - diabetes and weight gain
Risperidone - movement disorders and breasts/gynecomastia
Quetiapine - lowers movement disorders (goodfor movement disorders)
Ziprasidone - qt prolongation
Clozapine - agranulocytosis (monitor CBC)
Antipsychotics least likely to cause weight gain or diabetes
Aripiprazole or ziprasidone
Tx for Acute dystonia Akathisia Tardive dyskinesia NMS
Benztropine or diphenhydramine
Beta blocker and switch to an atypical
Switch to an atypical
Dantrolene or bromocriptine
Tx for panic disorder
Ssri
Tx for panic attack
Benzo (alprazolam)
Treatment for performance anxiety
Beta blocker like propanolol or atenolol
Treatment for OCD
SSRi Plus exposure and response therapy
Treatment for opiate intoxication and withdrawal
Intoxication - naloxone
Withdrawal - methadone or buprenorphine
Treatment for somatic symptom disorder
Psychotherapy
Anorexia versus bulimia
Answers always anorexia if they cannot maintain normal body weight
What medication has been effective for Binge eating disorders
Topiramate
Treatment for narcolepsy
Forced daytime naps and modafinil
Treatment for insomnia
First try sleep hygiene and then can add Z drug
Gastric lavage to be used for pill ingestion…
One patient arrives under two hours from ingestion
common brain frinding in schizophrenia?
enlarged cerebral ventricles
tx for catatonia
benzo (lorazepam) or ECT