Psych Flashcards
Obsessive Compulsive personality disorder
pre-occupied with orderliness, perfectionism and Control.
Egosyntonic nature of symptoms (believe he is superior)
No insignt to his behaviour.
MDD diagnosis:
symptoms > 2 weeks
5/9 symptoms:
SIGECAPS:
S: Suicidlity
I: loss of interest
G: guilt/ worthlesness
E: Energy low
C: concentration low
A: apetite
P: psychomotor agitation
S: sleep disturbance (insomina)
DD of Depressed mood
- MDD > 2 weeks
- Persistent depressive disorder (chronic depressed mood > 2 years, with 2 symptoms)
- Adjustmant disorder (known within 3 months of a known stressor)
Management of adjustmant disorder ?
Psychotherapy
Buproprion is Contraindicated in
Bulemia Nervosa
CF of Tardive Dyskinesia
Lipsmacking
Choreoathetoid movement ( trunk movment)
Pathophysiology of Tardive dyskinesia
Hypersensitivity of dopamine receptors, in view of prolonged blockage of D2 receptors by anti-psychotics.
MC in first generation anti-psych and resperidone
Schizoid Personality disorder
lonely, detached, unemotional
Schizotypal
unusual thoughts, perception or behavior.
Borderline personality disorder ( Cluster C)
He is on the border of impulsivity, anger and suicidal ideation.
Unstable relationsips
CF of catatinia
Unresponsivness
mutism
staring blankly
waxy flexebility
posturing
Management of catatonia ?
- benzo (lorazepam)
- Electroconvulsive therapy
MDD with psychotic features ?
loss of concentration
lack of energy
Inability to sleep
delusions or hallucinations related to low self esteem.
Indications of Hospitalization in Anorexia Nervosa ?
- bradycardia
- dehydration
- BMI less than 15
- electrolyte imbalance
- hypothermia
Malingering
falsification of info to gain external reward
Factitious disroder
Falsification of symptoms without obvious external reward
Rx of ADHD ?
Methylphenidate ( addictive)
Atomoxetine
DD between somatic symptom disorder and Illness anxiety disorder ?
- SSD: the pre-occupation with a specific symptom, causing distress and functional impairment
- IAD: worry about being ill with nonsymptoms.
REM sleep behavior disorder
- Common in patients with neurodegenrative diseases (parkinsons or dementia).
- Absence of atonia while in REM cycle.
- Able to wake up patient where he is at first confused and then fully awake
Sleep Terro ?
Unable to awaken the sleeping person.
nightmare
Patient remembers disturbing sleep content, but there is no motor activity
Mnagament of MDD ?
1- single episode: continue treatment for 6 months, if well, consider tapering
2- If patient has recurrent episodes: consider maintenance to 1-3 years
3- In case of highly recurrenl episdoes: to be taken indefinitely
Management of Acute dystonias ?
Benztropine or Diphenhydramine
( Anticholinergic and Anti-muscarinic).
Pharmaco
Indication of MOA-I
Refractory depression
Mechanism of Action of MOA-I ?
Inhibits the metabolism of monoamines ( NEP, Seretonin and Dopamine) also inhibits the metabolism of tyramine
Mech of action of tyramine ?
Facilitate the release of Monoamines, leading to sympathomimetic symptoms like HTN and headaches
causes a hypertensive crisis.
Serotonin Syndrome ?
Altered mental status ( confusion, anxiety, delerium)
Autonomic symptoms ( tachycardia, htn, vomiting, dilated pupils, hyperthermia, diaphoresis)
Neuromuscular Hyperactivity ( myoclonus, hyperreflexia ad tremor).
How to avoid Serotonin syndrome ?
All anti-depressants should be stopped 2 weeks before initiating MOA-I
Management of Psychotic depression ?
1-Anti-depressant + anti-psychotic
2- or ECT
ECT has a faster onset of action.
Indications of ECT
1- RX resistance
2- Psychotic Features
3- Emergency: pregnancy, inability to eat and drink, imminent risk of suicide
Benzo Withdrawal
Anxiety
Restlessness
Insomnia
tremors
psychosis and seizures
SE of valproate
drug induced liver injury
Addictions
What type of food contain tyramine ?
cured cheese, meat, alcohol
Chronic Methamphetamine Use
1- Pasranoid delusions ( including visual)
2- Tactile hallucinations
3- skin picking (skin sores), bruxism (decayed teeth with poor dentition).
4- agressive bahviour
Symptoms of ympathetic overactivity
becuase it is a CNS stimulant
Mech of action of Bupropione
Norepinephrine and Dopamine reuptake inhibitor.
Indication of Bupropione
Augmentation of effect of SSRI