Psych Flashcards

1
Q

SSRIs

A

Fluoxetine, citalopram, sertraline, fluvoxamine, escitalopram

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2
Q

Use of SSRIs

A

Depression, panic disorder, ocd

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3
Q

SSRIs with fewer drug interactions

A

Citalopram & escitalopram

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4
Q

SSRI contraindications

A

MAO inhibitors (hyperthermia & CV collapse)
Caution in epilepsy & peptic ulcer disease
PPI if with aspirin or nsaids

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5
Q

SSRI adverse effects

A

8S
Size, Sick, Serotonin syndrome, Sexual dysfunction, Stomach upset, Stress, Suicide, Sleep difficulty, Sodium (low)

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6
Q

Serotonin syndrome

A

Triad of autonomic hyperactivity, altered mental state and neuromuscular excitation

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7
Q

What is a SNRI & example

A

Serotonin & Noradrenaline Reuptake Inhibitors

Venlafaxine, Duloxetine

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8
Q

Use of SNRI

A

When SSRI ineffective for depression
Generalised anxiety disorder (venlafaxine)

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9
Q

Noradrenergic & Specific Serotonin Antidepressant example

A

Mirtazapine

(Alpha 2 adrenoreceptor antagonists)

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10
Q

MAO - I

A

Monoamine oxidase inhibitors
Ipronoazid, Selegiline

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11
Q

Tricyclic antidepressants examples

A

Amitriptyline, imipramine, lofepramine

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12
Q

Tricyclic contraindications

A

Recent MI or Arrhythmia
Manic phase
Severe liver disease
Epilepsy
other anticholineric drugs, alcohol & adrenaline
Lidocaine

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13
Q

Adverse effects of tricyclics

A

Muscarinic blocking (dry mouth, blurred vision, constipation)
A-adrenergic blocking (postural hypotension)
Noradrenaline uptake block in heart (arrhythmias)
Histamine blocking - sedation
Weight gain

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14
Q

Categories of antidepressant

A

SSRI
SNRI
NaSSA
MAO-I
Tricyclics

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15
Q

Mood Stabilisers

A

Lithium
Carbamazepine
Sodium valproate
Lamotrigine

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16
Q

Anxiolytic drugs =

A

Reduced anxiety
Can induce sleep in high doses

17
Q

Hypnotic drug =

A

Induces sleep. Can calm in low doses

18
Q

Examples of anxiolytics/ tranquillisers

A

Benzodiazepines
Z drugs

19
Q

Benzodiazepines examples

A

Midazolam, lorazepam, diazepam, chlordiazspoxide

20
Q

What do benzos do

A

Enhance inhibitors neurotransmitter gaba by increasing frequency of chloride channels. Used in insomnia, anxiety, alcohol withdrawal, acute main or psychosis (sedation)

21
Q

Z drug

A

Zopiclone

22
Q

Typical antipsychotics

A

Haloperidol, molindone, chlorpromazine

23
Q

What do typical antipsychotics do

A

Dopamine cholinergic adrenergic and histaminergic antagonists

24
Q

Atypical antipsychotics

A

Olanzapine clozapine aripiprazole
Rispiridone
Quetiapine