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CP2 - DERMATOLGY > Psoriasis > Flashcards

Psoriasis Flashcards

1
Q

What % of the population have psoriasis

A

2%

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2
Q

What are the 2 ages groups that get psoriasis?

A

Late teens

50s

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3
Q

Aetiology psoriasis (3)

A

FHx
Enviro
HLA-CW6

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4
Q

What is the most common type of psoriasis

A

Chronic plaque psoriasis

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5
Q

Features chronic plaque psoriasis (7)

A 
Salmon pink patches /plaques
Well demarcated 
Silver scale
Extensors 
Symmetrical 
Nail changes
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6
Q

Nail changes seen in psoriasis (3)

A

Pitting
Onycholysis
Subungal hyperkeratosis

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7
Q

DDx flexural psoriasis (3)

A

Eczema
Heat rash
Fungal infection

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8
Q

Areas affected by flexural psoriasis (5)

A 
Armpits 
Penis 
Umbilicus 
Under breasts 
Natal cleft
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9
Q

Who gets guttate psoriasis

A

Children/adolescents

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10
Q

Cause guttate psoriasis

A

Acute strep infection

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11
Q

Appearance guttate psoriasis

A

Rain drop lesions

In linear configuration

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12
Q

What may guttate psoriasis precede?

A

Chronic plaque psoriasis

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13
Q

What % body SA is affected in erythrodermic psoriasis?

A

> 90%

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14
Q

Who gets palmoplantar pustular psoriasis

A

F
ADults
who are smokers

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15
Q

What precipitates generalised pustular psoriasis

A

Steroid withdrawal

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16
Q

Appearance generalised pustular psoriasis

A

sheets pustules

+ background erythema

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17
Q

What is the Koebner phenomenon

A

Tendency for a skin condition to occur within scars or sites of trauma

18
Q

What area of the body is hardest to get rid of psoriasis from?

A

Legs

19
Q

Aggravating factors psoriasis (7)

A 
Strep 
Medication
Stress 
Alcohol 
Cigarettes 
Trauma 
Friction
20
Q

What medications can aggravate psoriasis?

A

Beta blockers
Lithium
Anti-malarials

21
Q

At what DLQI score would you consider psychological intervention?

A

> 10

22
Q

What score determines the serverity of psoriasis?

A

PASI

23
Q

How is the PASI score calculated?

A

Redness
Thickness
Scaling

24
Q

A PASI score of what would indicate systemic treatment should be commenced?

A

> 10

25
Q

1st line Tx psoriasis

A 
Emollients e.g. E45
Calcipotriol 
TO CCS e.g. eumovate
Keratoyltics - salicylic acid 
Coal tar
Dithranol
26
Q

1st line Tx thick plaques

A

Salicylic acid

Dithranol

27
Q

1st line Tx guttate psoriasis (4)

A

Emollients
Coal tar
Clcipotriol dovonex
TL01 UVB

28
Q

Specific Tx - scalp psoriasis

A

Cocois
Coal tar shampoo
TO CCS scalp application

29
Q

Specific Tx - face psoriasis

A

Mild TO CCS - 1% HC

30
Q

Specific Tx - flexural psoriasis

A

Calcitriol ointment

31
Q

SE - phototherapy (3)

A

Erythema/pruritis
Nausea
Skin cancer

32
Q

Mx Eryhthrodermic psoriasis, generalised pustular psoriasis

A

Admit
Supportive
Liberal emollients/potent TO steroids

33
Q

3rd line Tx psoriasis (3)

A

Methotrexate
Ciclosporin
Acitretin

34
Q

Methotrexate SE

A 
Teratogenicity 
Nausea
GI upset 
Liver fibrosis 
Marrow suppression
35
Q

What MUST be monitored inf on methotrexate

A

LFT

FBC

36
Q

SE ciclosporin

A 
HTN
Nephrotoxicity 
Carcinogenesis 
Gym hypertrophy 
Tingling peripheries
37
Q

What must be monitored if on ciclosporin

A

BP

U+E

38
Q

How long is acitretin teratogenic for?

A

2 years

39
Q

SE acitretin (4)

A

Dry skin
Dry lips
Hyperlipidaemia
Hepatotoxicity

40
Q

What must be monitored if on acitretin

A

Fasting lipids

LFTs

CP2 - DERMATOLGY (7 decks)

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