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YR5 Derm > Psoriasis > Flashcards

Psoriasis Flashcards

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Dermatology Board Prep flashcards
1
Q

Describe the aetiology of psoriasis

A

Genetic predisposition with trigger of inflammatory response (infection, irritation, drugs)

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2
Q

4 subtypes of psoriasis

A

Plaque
Guttate
Pustular
Erythrodermic

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3
Q

5 features of plaque psoriasis

A

Raised inflamed thick superficial silvery-white scaly erythematous lesions
Most common
Symmetrical distribution, extensor surfaces
Onycholysis + nail pitting
Koebner phenomenon

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4
Q

3 features of guttate psoriasis

A

Widespread, erythematous, fine, scaly papules (water drop appearance)
Scattered on trunk + limbs
Lesions often erupt after URTI

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5
Q

4 features of erythrodermic psoriasis

A

Generalised erythema with fine scaling.
Pain, irritation, + severe itching
Malaise , fever + dehydration
Skin feels hot + uncomfortable

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6
Q

4 features of generalised pustular psoriasis

A

Generalised erythroderma
Confluent white pustules over whole body
Involvement of mucosa + tongue
Correlation with HLA-B27

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7
Q

What is koebner phenomenon?

A

New skin lesions of pre-existing dermatosis in areas of cutaneous injury in otherwise healthy skin

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8
Q

Dx of psoriasis

A

Clinical

Biopsy if unsure

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9
Q

3 features of localised pustular psoriasis

A

Palmo-plantar commonly
Sterile pustules or erythema base
Not itchy

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10
Q

Tx for plaque psoriasis

A

Topical corticosteroid + Vitamin D analogue

e.g. Hydrocortisone + Calcipotriol

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11
Q

2 Tx options for severe plaque psoriasis

A

Phototherapy

Oral Methotrexate / Ciclosporin

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12
Q

Tx for erythemodermic psoriasis

A

Oral Ciclosporin

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13
Q

Tx for guttate psoriasis

A

Phototherapy

Oral Methotrexate / Ciclosporin

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14
Q

Tx for generalised pustular psoriasis

A

Acitretin/ Ciclosporin/ Methotrexate

IV fluids

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15
Q

5 risk factors for generalised pustular psoriaisis

A 
Systemic steroid withdrawal
Pregnancy
Infection
Hypocalcaemia 
Drugs e.g. Aspirin, Lithium, some BBs
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16
Q

Tx for erythrodermic psoriasis

A

Acitretin/ Ciclosporin/ Methotrexate

IV fluids

17
Q

5 patterns of psoriatic arthropathy

A 
Asymmetrical Mono- or oligoarticular
Symmetric polyarthropathy
DIP arthritis
Arthritis mutilans
Spondylitis with sacroiliac + spinal involvement
18
Q

Tx of psoriatic arthropathy

A

NSAIDs

DMARDs e.g. Methotrexate if progressive

19
Q

Which 6 drugs exacerbate plaque psoriasis?

A 
B blockers
Antimalarials
Lithium
NSAIDs
ACEi
Infliximab
20
Q

What 3 factors may exacerbate plaque psoriasis?

A

Trauma
Alcohol
Withdrawal of systemic steroids

YR5 Derm (14 decks)

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