Psoriasis Flashcards

1
Q

Types de Pso pustuleux

A
Pso pustuleux généralisé (Von Zumbusch)
Palmoplantaire
Annulaire
Sneddon-Wilkinson (dermatose pustuleuse sous cornéenne)
Exanthématique 
Localisé
Acrodermatite continua de Hallopeau
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2
Q

Differentiel Pso linéaire

A

ILVEN

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3
Q

Differential Pso erythrodermique

A

PRP, AD, Sezary

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4
Q

Triggers Pso pustuleux généralisé

A

Grossesse (impétigo herpetiformis)
Sevrage cortico
HypoCa
Infections

Souvent avec fièvre (comme Hallopeau)

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5
Q

Differentiel plus rare de Pso cuir chevelu

A

Dermatomyosite

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6
Q

Differentiel plus rare de Pso inversé

A

Parakeratose granuleuse

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7
Q

Sneddon Wilkinson caractéristiques

A

Débute dans les plis
Annulaire
Pustules superficielles sur les bords
Niveau de pus

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8
Q

Spondylarthrite et sacroiliite associations

A

HLA B 27
Maladie inflammatoire du tube digestif
Uvéite

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9
Q

Differentiel arthrite psoriasique

A
Arthrite réactionnelle (Reiter )
Urethrite 
Conjonctivite 
Ulceres oraux
Lesions psoriasiformes plantaires et génitales (balanite circinée)
HLAB 27, hommes 
Sévère chez HIV +
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10
Q

Dose max de calcipotriol

A

100g par semaine

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11
Q

Contre indication calcipotriol

A
Large surface 
Anomalie de métabolisme du Ca où des os 
Insuf rénale 
Allergie
Grossesse/allaitement
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12
Q

Conter indications MTX

A
Insuf rénale
Insuf hépatique, fibrose, ROH
Medication hepatotoxique 
Interaction medicamenteuse (septra)
Fonction pulmonaire réduite 
Ulcère peptic actif 
Ascite/épanchement pulmonaire 
Patient non fiable
Grossesse/allaitement, planification de conception 
Infections sévère 
Immunossupression
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13
Q

Bilan biologique

A
PPD/Quantiferon
Rx pulmonaire 
FSC
HIV, sérologies hépatite B et C
Recherche infection chronique, Neo, troubles neurologiques et maladies cardiaques (insuf cardiaque et anti TNF)
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14
Q

Grossesse + Pso tx systémique

A

UVB
Biologiques (anti TNF, ustekinumab cat B)
Cyclosporine (Cat C)

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15
Q

Hépatite B/ C et tx syst Pso

A

Etanercept #1

Adalimumab , ustekinumab

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