PSGS Review 2019 Flashcards
50/F came in with 1 cm left breast mass. Mammogram showed architectural deformity. Ultrasound showed a hypoechoic, microlobulated mass. 1 xillary node noted as well 5cm in size with fatty hilum. What would be the next best step in management?
A) excision biopsy of breast mass
B) excision biopsy of breast mass and axillary node
C) ultrasound-guided core needle biopsy of breast mass
D) ultrasound-guided core needle biopsy of breast mass and axillary node
C) ultrasound-guided core needle biopsy of breast mass
35/F underwent partial mastectomt with sentinel node biopsy for breast cancer. Histopath report as follows: invasivd mammary carcinoma 1cm Grade I, 0 out of 4 sentinel lymph nodes positive for tumor, ER + PR + Her2neu -. Next step in management would be: A) adjuvant anastrazole B) Oncotype DX C) Chemotherapy D) Radiotherapy
B) Oncotype DX
38/F came in for a 4cm breast mass. Ultrasound-guided core needle biopsy showed ductal carcinona in situ, grade 2. Surgical options for the patient would include:
A) Lumpectomy with sentinel node biopsy
B) Mastectomy with sentinel node biopsy
C) Mastectomy with axillary node dissection with immediate reconstruction
D) Mastectomy with axillary node dissection eith delayed reconstruction
B) Mastectomy with sentinel node biopsy
50/F diagnosed with Stage I (T1N0M0) breast cancer underwent mastectomy with sentinel node biopsy. Intraoperstivelt, frozen section relayed showed isolated tumor cells in 2 of 4 sentinel nodes. Appropriate surgical action for this patient is: A) node picking B) level I and II node dissection C) nothing more D) level I, II and III dissection
C) nothing more
45F underwent mastectomy with sentinel node biopsy. Final histopath showed: ductal carcinoma in situ, 30mm in widest diameter, grade 1, with areas of necrosis, nearest margin is basal margin 3mm, with 2mm foci of invasion, 2 sentinel nodes negative for tumor xells; ER + PR + Her2neu +. Appropriate postoperative management is
A) Tamoxifen 20mg OD
B) Tamoxifen 20mg OD, followed by chemotherapy
C) Tamoxifen 20mg OD, followed by chemotherapy and Trastuzumab
D) Tamoxifen 20mg OD, followed by chemotherapy and Trastuzumab, followed by radiotherapy
A) tamoxifen 20mg OD
Importance of Her2neu in DCIS has not yet been elucidated
ALND not recommended
25% of DCIS will have invasive component
60F recently underwent partial mastectomy with sentinel node biopsy for breast cancer. Final histopath showed mucinous carcinoma, 4cm widest diameter, Grade I, negative for lymphovascular space invasion, nearest margin is basal margin 1mm, 3 sentinel nodes negative for tumor cells ER + PR + Her2neu -. Appropriate management is
A) Letrozole 2.5mg OD, followed by radiotherapy
B) Letrozole 2.5mg OD, followed by chemotherapy
C) Letrozole 2.5mg OD, followed by chemotherapy, followed by radiotherapy
D) Tamoxifen 20mg OD
A) Letrozole 2.5mg OD, followed by radiotherapy
90% of mucinous are ER PR positive
50F came in due to eczematous lesion of the right nipple. Most appropriate next step is:
A) punch biopsy
B) mammogram and breast ultrasound
C) MRI
D) refer to dermatology
B) mammogram and breast ultrasound
Consider Paget’s disease
55F recently underwent mastectomy with axillary node dissection fof breast cancer. The following histopath: invasive mammary carcinoma, 50mm, Nottingham grade III, with lymphovascular invasion, nearest margin anterior margin 1mm, 1 of 20 axillary nodes positive for tumor cells ER - PR + Her2neu -. Appropriate management is
A) Tamoxifen 20mg OD
B) Tamoxifen 20mg OD, chemotherapy
C) Tamoxifen 20mg OD, chemotherapy, radiotherapy
D) Tamoxifen 20mg OD, chemotherapt, radiotherapy, Trastuzumab
C) Tamoxifen 20mg OD, chemotherapt, radiotherapy
60F underwent partial mastectomy with sentinel nodevbiopsy. Histopath showed:
Invasive mammary carcinoma, 1cm, Nottingham grade I, no lymphovascular space invasion, 1/4 sentinel nodes positivd for tumor cells. ER+ PR+ Her2neu-. According to the Z11 trial, appropiate management is:
A) minimal axillary node dissection followed by Anastrazole @mg OD
B) Anastrazole 1mg OD, chemotherapy, radiotherapy
C) Anastrazole 1mg OD
D) Tamoxifen 20mg OD
B) Anastrazole 1mg OD, chemotherapy, radiotherapy
58F underwent right modified radical mastectont for a 3cm invasive ductal carcinoma. Lymph nodes are negative. The tumor is ER+ PR- Her2neu 1+. The next step is:
A) Fluorescence in situ hybridization testing of the breast tumor
B) Aromatase inhibitor may be included in adjuvant treatment
C) Postoperative radiation is warranted
D) Treat with Trastuzumab for 1 year
A) Fluorescence in situ hybridization
Level III axillary lymph nodes are:
A) lateral to the pectoralis minor muscle
B) Rotter’s nodes
C) medial to the pectoralis minor muscle
D) usually removed during modified radical mastectomy
C) medial to the pectoralis minor muscle
Mammographic findings highly suggestive of benignity: A) clustered microcalcifications B) changing microcalcifications C) pleomorphic calcifications D) scattered macrocalcifications
D) scattered macrocalcifications
35M presented with a non-movable mass in the left hemiabdomen. Magnetic resonance imaging showed a 23 x 16 x 14 cm retroperitoneal tumor involving the aorta thus seemed unresectable. There is no sign and symptom of bowel obstruction. Next option is:
A) radiation therapy followed by chemotherapy
B) chemotherapy
C) core needle biopsy of the tumor
D) radiofrequency ablation
C) core needle biopsy of the tumor
56M with a 1.5 cm ulceration in the forehead. Incision biopsy done showing basal cell carcinoma. Your next procedure of choice is:
A) wide excision with sentinel node biopsy
B) mohs surgery
C) interleukin injection of tumor
D) wide local excision with flap rotation surgery
B) Moh’s surgery
A patient with a necrotizing soft tissue infection on his right lower extremity was admitted to the ER. His vital signs were: BP 70/50 HR 110 RR 25 T 39. O2 sat 88%. ABGs showed pH 7.25 PaCO2 25mmHg HCO3 12 PaO2 79mmHg FiO2 0.3. His electrolytes were Na 133 K 3.8 Cl 100. Despite adequate initial fluid infusion, patient remained hypotensive. The best hemodynamic drug to give is:
A) dopamine
B) norepinephrine
C) dobutamine
D) epinephrine
B) norepinephrine