Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

4. Monoarticular joint pain > Pseudogout > Flashcards

Pseudogout Flashcards

1
Q

What is the diagnosis from this xray?

A

CPPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What will polarised light microscopy of the synovial fluid from a joint with pseudogout show?

A
  • weakly positive birefringent
  • rhomboid shaped crystals
  • of crystal-calcium pyrophosphate
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is chondrocalcinosis?

A

soft tissue calcium deposition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the 3 types of pseudogout?

A
  1. sporadic (irregular/unknown)
  2. heredity
  3. secondary
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is pseudogout also known as?

A

Calcium pyrophosphate dihydrate disease (CPPD)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the clinical features of acute synovitis?

A
  1. pain
  2. swelling
  3. stiffness
  4. occasionally fever
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What 4 metabolic diseases predispose to calcium pyrophosphate dihydrate disease?

A
  1. hypothyroidism
  2. hyperparathyroidism
  3. acromegaly (overproduction of the growth hormone)
  4. gout
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where is chondrocalcinosis most commonly seen on x ray?

A
  1. in the menisci of the knee
  2. triangular cartilage of the wrist
  3. symphysis pubis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What will an X-ray of a joint with psuedogout look like?

A

white lines of chondrocalcinosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is calcium pyrophosphate dihydrate disease?

A

an arthropathy associated with the deposition of CPPD crystals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the clinical features of chronic pyrophosphate arthropathy?

A
  • gradual onset of pain
  • swelling
  • loss of joint function
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What causes the autosomal dominant variant of CPPD?

A
  • germline mutations in the pyrophosphate transport chain
  • resulting in crystal deposition
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the two main clinical presentations of CPPD disease?

A
  1. acute synovitis
  2. chronic pyrophosphate arthroplasty
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How can pseudogout be treated?

A
  1. analgesia, NSAIDS
  2. joint aspiration, intra-articular steroids
  3. cholchicine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Is gout or pseudogout more common?

A

gout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which joints are most commonly affected by pseudogout, from most to least?

A
  1. knees
  2. wrists
  3. elbows
  4. shoulders
  5. ankles
17
Q

What is the pathophysiology behind pseudogout?

A
  • articular cartilage proteoglycans are degraded
  • allowing crystallisation around chondrocytes

4. Monoarticular joint pain (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions