PSA revision Flashcards
aName some enzyme inducers
PC BRAS:
Phenytoin
Carbamazepine
Barbiturates
Rifampicin
Alcohol
Sulphonylureas
Name some enzyme inhibitors
AO DEVICES
Allopurinol
Omeprazole
Disulfiram
Erythromycin
Valproate
Isoniazid
Ciprofloxacin
ethanol
Sulphonamides
What medications are most likely to cause delirium
BDZs
Zopiclone
Opioids
Anticholinergics
Pregabalin
]Antipsychotics
Metoclopramide
Thiazide diruetics
Diuretics
What defines insensible water loss
500-800ml
What is the daily water requirement in an adult
25-30ml/kg/day of water
How much sodium and potassium is required per kg/day
1mmol
What are crystalloid fluids
Soultion of mineral salts
How can we measure for hydration status
Weight
Name a hypertonic solution
Mannitol (draws fluid out of cells)
What is the first line IV fluid therapy for [atients who are dehydrated
0.9% Sodium Chloride 500ml over less than 15 minutes
What is the second line IV fluid therapy for patients who are dehydrated
Human Albumin Solutino (colloid solution)
What is the minimum urine output to aim for in fluid resuscitation
0/5 ml/kg/day
If a patient loses 1500 ml of blood, what is the equivalent volume replacement with a colloid
1500 ml
What are enteric coating drugs
Protects the drug from the stomach lining as it needs absorbing in the small intestines
When should your variable rate insulin be stopped
Around 30-60 minutes after a meal
At what eGFR is nitrofurantoin contraindicated
<45
What antibiottic can cause heaptic jaundice
Clarithromycin
By how much do we increase someone’s insulin dose
By 10-20%
1mg = how many mL?
10mL
How often do Digoxin levels need to be checked
Every 6 hours
What side effect should be looked out for in a patient just started on warfarin
Easy bruising