PSA- common conditions Flashcards
management of chronic asthma
1) SABA eg salbutamol
2) Inhaled corticosteroid
3) LTRA-montelukast
4) LABA-eg salmeterol (stop LTRA if not helping)
5) MART- maintenance and release therapy- ICS plus fast acting LABA
6) theophyline/ tiotropium
side effects of salbutamol/ SABA
hypokalaemia
arrhythmia, tremor, palpitations, headache
drugs not to prescribe in asthma
NSAIDs- bronchospasm
betablockers-
adenosine (also CI in COPD)
management of acute asthma
1) Oxygen
2) SABA
3) Steroid- oral pred/ IV hydrocortisone
4) Nubuslied ipratropium bromide
5) magnesium sulphate
6) IV aminophyline
loading dose of aminophyline in acute asthma?
5mg/kg SLOW IV injection over at least 20 mins
available in 25mg/ml ampules
target plasma concentration of aminophyline
when to measure aminiphylline concs?
10-20 micrograms/mL
measure 18 hours after starting treatment or sooner if concerns about toxicity
Management of chronic COPD
Stop smoking, flu vaccine and pneumococcal vaccine, pulmonary rehabilitation
1) SAMA (ipratropium bromide) / SABA (salbutamol)
2) determine whether asthmatic features and steroid responsive
NO ASTHMATIC FEATURES/ NOT STEROID RESPONSIVE
3) LABA +LAMA (tiotropium), (stop SAMA)
4) ICS
STERIOD RESPOSIVE/ ASTHMATIC
3) LABA+ ICS- fostair, symbicort, seretide
4) LABA+ LAMA+ ICS (stop SAMA)
prolonged or frequent infective exacerbations:
prophylactic azithromycin
management of exacerbation of COPD
AT HOME
1) Prednisolone 30mg once daily for 7-14 days
2) Regular inhalers or home nebulisers
3) Antibiotics if there is evidence of infection
IN HOSPITAL
1) Nebulised SABA/ SAMA
2) IV/PO steroids
3) antibiotics- amoxicillin/ doxycyline
4) physio
5) IV aminophylline
6) NIV
7) intubation and ventilation
Target saturations for COPD
88-92%
Venturi 28% mask, 4L, until blood gases can be measured to determine of retaining CO2
Management of angina
ACUTE
- GTN (glyceryl trinitrate)
- repeat after 5 mins, call ambulance if pain still present after another 5 mins
LONG TERM
1)betablocker- atenolol/ bisoprolol
(CCB eg verapimil if CI)
2) BB + CCB (long acting nitrate eg ivabridine if either CI)
SECONDARY PREVENTION OF CARDIOVASCULAR DISEASE
- lifestyle
- low dose aspirin and statin if atherosclerotic disease
- ACE-I if diabetes
acute management of unstable angina/ NSTEMI
MONA ABC
- morphine 5-10mg IV
- oxygen if desaturating <96%
- GTN
- Asprin 300mg
ABC
- Anticoagulant- LMWH eg enoxaparin 1mg/kg BD
- Betablocker- continued indefinitely (verapimil/diltaziem if CI)
- Clopidogrel
GRACE Score-
PCI if high risk (NEVER THROMBOLYSIS)
Secondary prevention of ACS
6As
Aspirin 75mg OD
Another antiplatelet- clopidogrel/ticagrelor for 12 months
Atorvostatin 80mg OD
ACE-I- ramipril
Atenolol
Aldosterone antagonist if clinical heart failure
plus lifestyle changes
acute management of STEMI
MONA
PCI if available <90 mins after diagnosis + LMWH
or
Thrombolysis if not available- streptokinase+ LMHW
A(2)BC -Anticoagulant (LMWH) +ACE-I (continued for 5-6 weeks) -Betablocker -Clopidogrel D- diabetes- monitor for hyperglycaemia
Management of Gastro-oesophageal reflux disease (GORD)
- lifestyle changes
- PPI (lansoprazole)
- if no response after 4-8 weeks–> H2 receptor antagonist (ranitidine)
1st line medical treatment of depression
SSRI eg citalopram, fluoxetine, sertraline